FR2196805A1 - 2-(3,5-di-tert-butylphenyl)indane-1,3-dione - anti-inflammatories and anal-gesics with little or no anticoagulant and ulcerogenic activity - Google Patents
2-(3,5-di-tert-butylphenyl)indane-1,3-dione - anti-inflammatories and anal-gesics with little or no anticoagulant and ulcerogenic activityInfo
- Publication number
- FR2196805A1 FR2196805A1 FR7330165A FR7330165A FR2196805A1 FR 2196805 A1 FR2196805 A1 FR 2196805A1 FR 7330165 A FR7330165 A FR 7330165A FR 7330165 A FR7330165 A FR 7330165A FR 2196805 A1 FR2196805 A1 FR 2196805A1
- Authority
- FR
- France
- Prior art keywords
- gesics
- inflammatories
- indane
- anticoagulant
- butylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ITVMYFGQCMFWIN-UHFFFAOYSA-N 2-(3,5-ditert-butylphenyl)indene-1,3-dione Chemical compound CC(C)(C)C1=CC(C(C)(C)C)=CC(C2C(C3=CC=CC=C3C2=O)=O)=C1 ITVMYFGQCMFWIN-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 229940035676 analgesics Drugs 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 229940127219 anticoagulant drug Drugs 0.000 title 1
- 230000014508 negative regulation of coagulation Effects 0.000 title 1
- 230000001562 ulcerogenic effect Effects 0.000 title 1
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- WNZQDUSMALZDQF-UHFFFAOYSA-N 2-benzofuran-1(3H)-one Chemical compound C1=CC=C2C(=O)OCC2=C1 WNZQDUSMALZDQF-UHFFFAOYSA-N 0.000 abstract 2
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 2
- ISSUIBOUOMNCOX-UHFFFAOYSA-N 3-benzylidene-4-butyl-2-benzofuran-1-one Chemical compound C(CCC)C1=C2C(OC(=O)C2=CC=C1)=CC1=CC=CC=C1 ISSUIBOUOMNCOX-UHFFFAOYSA-N 0.000 abstract 1
- ARIREUPIXAKDAY-UHFFFAOYSA-N 4-butylbenzaldehyde Chemical compound CCCCC1=CC=C(C=O)C=C1 ARIREUPIXAKDAY-UHFFFAOYSA-N 0.000 abstract 1
- LDOXTQYWWYXYSQ-UHFFFAOYSA-N Butyl phenylacetate Chemical compound CCCCOC(=O)CC1=CC=CC=C1 LDOXTQYWWYXYSQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 235000019439 ethyl acetate Nutrition 0.000 abstract 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3893972 | 1972-08-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2196805A1 true FR2196805A1 (en) | 1974-03-22 |
| FR2196805B1 FR2196805B1 (cs) | 1976-08-13 |
Family
ID=10406617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7330165A Granted FR2196805A1 (en) | 1972-08-21 | 1973-08-20 | 2-(3,5-di-tert-butylphenyl)indane-1,3-dione - anti-inflammatories and anal-gesics with little or no anticoagulant and ulcerogenic activity |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5046815A (cs) |
| BE (1) | BE803797A (cs) |
| DE (1) | DE2342061A1 (cs) |
| FR (1) | FR2196805A1 (cs) |
| NL (1) | NL7311431A (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3616215A1 (de) * | 1986-05-14 | 1987-11-26 | Israel Melcer | Sandale |
-
1973
- 1973-08-20 BE BE134745A patent/BE803797A/xx unknown
- 1973-08-20 JP JP9322673A patent/JPS5046815A/ja active Pending
- 1973-08-20 NL NL7311431A patent/NL7311431A/xx unknown
- 1973-08-20 FR FR7330165A patent/FR2196805A1/fr active Granted
- 1973-08-20 DE DE19732342061 patent/DE2342061A1/de active Pending
Non-Patent Citations (1)
| Title |
|---|
| RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS" 85 1966 PAGES 1259 A 1262) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3616215A1 (de) * | 1986-05-14 | 1987-11-26 | Israel Melcer | Sandale |
Also Published As
| Publication number | Publication date |
|---|---|
| BE803797A (fr) | 1974-02-20 |
| DE2342061A1 (de) | 1974-03-07 |
| NL7311431A (cs) | 1974-02-25 |
| FR2196805B1 (cs) | 1976-08-13 |
| JPS5046815A (cs) | 1975-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |