FR2193597A1 - Indenyl acetic acids prepn - by Grignard reaction of methyl-3,3-ethylenedioxy 1-oxoindane acetate - Google Patents

Indenyl acetic acids prepn - by Grignard reaction of methyl-3,3-ethylenedioxy 1-oxoindane acetate

Info

Publication number
FR2193597A1
FR2193597A1 FR7326476A FR7326476A FR2193597A1 FR 2193597 A1 FR2193597 A1 FR 2193597A1 FR 7326476 A FR7326476 A FR 7326476A FR 7326476 A FR7326476 A FR 7326476A FR 2193597 A1 FR2193597 A1 FR 2193597A1
Authority
FR
France
Prior art keywords
alkyl
methyl
alkenyl
ethylenedioxy
acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7326476A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2193597A1 publication Critical patent/FR2193597A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions

Abstract

Cpds. of formula (I): where R1 and R2 = H, halogen, alkyl, alkenyl, aryl, haloalkyl, alkylthio, arylthio, aralkylthio, (alkyl)amino, dialkylamino, acylamino, hydroxyl, alkenyloxy, alkynyloxy, aralkoxy, (halo)alkoxy, carboxyl, alkoxycarbonyl, aralkoxycarbonyl or an N-contg. heterocyclic gp.; R1 and R2 may form together an alkylene or keto gp.; R3 = H, (halo)alkyl, alkenyl, alkynyl or trihalomethyl; R4, R5, R6, R7, R8 and R9 = H, halogen, alkyl, acyloxy, aryloxy, alkoxy, nitro, (acyl)amino, (di)alkylamino, alkenyl, alkynyl, alkenyloxy, dialkylaminoalkyl, sulphamyl, alkylthio, alkylsulphinyl, alkylsulphonyl, hydroxyl, hydroxyalkyl, acyl, cyano, carboxyl, carboalkoxy, carbamido, haloalkyl, cycloalkyl, cycloalkoxy or aroyl; x = -O, -S, alkylene, alkenylene, alkynylene, sulphinyl, or sulphonyl or a gp. NR, where R = H or alkyl; Ar = aryl or heteroaryl; M = H, alkyl, alkenyl, alkynyl, alpha- or beta-glucoronide, glyceryl, alkoxyalkyl, alkanoyloxyalkyl, aroyloxyalkyl, a metal cation or an ammonium cation; n = 0 or 1. Prepn. by Grignard reaction to the methyl 3,3-ethylenedioxy-2-methyl-1-(p-methylsulphinylbenzylidene)indeny- l-6-acetate which is is warmed which is stirred in aq. pyridine to form (I).
FR7326476A 1972-07-21 1973-07-19 Indenyl acetic acids prepn - by Grignard reaction of methyl-3,3-ethylenedioxy 1-oxoindane acetate Withdrawn FR2193597A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390572A 1972-07-21 1972-07-21

Publications (1)

Publication Number Publication Date
FR2193597A1 true FR2193597A1 (en) 1974-02-22

Family

ID=23045925

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7326476A Withdrawn FR2193597A1 (en) 1972-07-21 1973-07-19 Indenyl acetic acids prepn - by Grignard reaction of methyl-3,3-ethylenedioxy 1-oxoindane acetate

Country Status (4)

Country Link
JP (1) JPS4943955A (en)
DE (1) DE2337120A1 (en)
FR (1) FR2193597A1 (en)
NL (1) NL7309425A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5277156A (en) * 1975-12-24 1977-06-29 Koodo Kk Resin composition for information recording body
DE102005010000A1 (en) * 2005-03-04 2006-09-07 Merck Patent Gmbh indanes

Also Published As

Publication number Publication date
NL7309425A (en) 1974-01-23
DE2337120A1 (en) 1974-02-07
JPS4943955A (en) 1974-04-25

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Legal Events

Date Code Title Description
ST Notification of lapse