FR2187909A1 - Stable antigens - by freeze-drying antigen bonded to red blood cells - Google Patents

Stable antigens - by freeze-drying antigen bonded to red blood cells

Info

Publication number
FR2187909A1
FR2187909A1 FR7220646A FR7220646A FR2187909A1 FR 2187909 A1 FR2187909 A1 FR 2187909A1 FR 7220646 A FR7220646 A FR 7220646A FR 7220646 A FR7220646 A FR 7220646A FR 2187909 A1 FR2187909 A1 FR 2187909A1
Authority
FR
France
Prior art keywords
antigens
antigen
drying
freeze
blood cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7220646A
Other languages
French (fr)
Other versions
FR2187909B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Priority to FR7220646A priority Critical patent/FR2187909A1/en
Priority to SU7301900044A priority patent/SU568378A3/en
Publication of FR2187909A1 publication Critical patent/FR2187909A1/en
Application granted granted Critical
Publication of FR2187909B1 publication Critical patent/FR2187909B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G01N33/555—Red blood cell

Abstract

Prepn. of antigens for passive haemagglutination, by inactivation of an antigen, bonding the antigen on to red cells and finally freeze-drying the bonded antigen. The antigens are stable for over 6 months compared with 1 or 2 weeks for usual antigens, e.g. that of foot-and-mouth disease. Non-enveloped viruses e.g. those of poliomyelitis and foot and mouth disease may be bound directly using a dialdehyde e.g. glutaraldehyde. Enveloped viruses such as those of measles, influenza, Newcastle disease, and swine fever are freed of the envelope e.g using Tween ether Viruses are killed with beta-propolactone before use. Antigens for bacterial toxins such as tetanus, botulism and diphtheria may be produced similarly.
FR7220646A 1972-06-08 1972-06-08 Stable antigens - by freeze-drying antigen bonded to red blood cells Granted FR2187909A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7220646A FR2187909A1 (en) 1972-06-08 1972-06-08 Stable antigens - by freeze-drying antigen bonded to red blood cells
SU7301900044A SU568378A3 (en) 1972-06-08 1973-03-14 Antigene preparation production process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7220646A FR2187909A1 (en) 1972-06-08 1972-06-08 Stable antigens - by freeze-drying antigen bonded to red blood cells

Publications (2)

Publication Number Publication Date
FR2187909A1 true FR2187909A1 (en) 1974-01-18
FR2187909B1 FR2187909B1 (en) 1975-03-28

Family

ID=9099888

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7220646A Granted FR2187909A1 (en) 1972-06-08 1972-06-08 Stable antigens - by freeze-drying antigen bonded to red blood cells

Country Status (2)

Country Link
FR (1) FR2187909A1 (en)
SU (1) SU568378A3 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000102A1 (en) * 1977-06-14 1978-12-20 American Home Products Corporation Immunologic compositions, methods for preparing them and methods for conducting haemagglutination tests
US4320111A (en) * 1977-06-14 1982-03-16 American Home Products Corporation Immunologic compositions methods of preparation and use
EP0183215A2 (en) * 1984-11-26 1986-06-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Method for determination of herpes simplex virus antibodies
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11634257B2 (en) 2017-10-09 2023-04-25 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, VOLUME 70, PAGE 104625U 1969 CITE: IMMUNOCHEMISTRY, VOLUME 6 1 , PAGES 67-76 1969 .) *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000102A1 (en) * 1977-06-14 1978-12-20 American Home Products Corporation Immunologic compositions, methods for preparing them and methods for conducting haemagglutination tests
US4320111A (en) * 1977-06-14 1982-03-16 American Home Products Corporation Immunologic compositions methods of preparation and use
EP0183215A2 (en) * 1984-11-26 1986-06-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Method for determination of herpes simplex virus antibodies
EP0183215A3 (en) * 1984-11-26 1986-12-30 Chemo Sero Therapeut Res Inst Method for determination of herpes simplex virus antibodies
US11634257B2 (en) 2017-10-09 2023-04-25 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11609042B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use
US11609043B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use
US11740019B2 (en) 2019-03-14 2023-08-29 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11747082B2 (en) 2019-03-14 2023-09-05 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use
US11815311B2 (en) 2019-03-14 2023-11-14 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use

Also Published As

Publication number Publication date
FR2187909B1 (en) 1975-03-28
SU568378A3 (en) 1977-08-05

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Legal Events

Date Code Title Description
ST Notification of lapse