FR2181731A1 - Adamantane-1-carboxamidine and derivs - antivirals - Google Patents

Adamantane-1-carboxamidine and derivs - antivirals

Info

Publication number
FR2181731A1
FR2181731A1 FR7305214A FR7305214A FR2181731A1 FR 2181731 A1 FR2181731 A1 FR 2181731A1 FR 7305214 A FR7305214 A FR 7305214A FR 7305214 A FR7305214 A FR 7305214A FR 2181731 A1 FR2181731 A1 FR 2181731A1
Authority
FR
France
Prior art keywords
adamantane
carboxamidine
derivs
antivirals
prepd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7305214A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2181731A1 publication Critical patent/FR2181731A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The novel title cpds. of formula (where R1 is H, OH or amino) and their salts, are prepd. by reacting a cpd. of formula (where X = O or S and R2 is (cyclo)alkyl, alkylaryl or aralkyl) with a cpd. R1-NH2 and opt. converting the prods. to their salts by reaction with mineral or organic acids. They may be prepd. by reacting A-C(=NH)-X-R2 (where A = adamantane, X = O or S and R2 = (cyclo)alkyl, alkylaryl or aralkyl) with R1NH2, and are esp. useful for the prevention of influenza.
FR7305214A 1972-02-15 1973-02-14 Adamantane-1-carboxamidine and derivs - antivirals Withdrawn FR2181731A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH218372A CH560678A5 (en) 1972-02-15 1972-02-15

Publications (1)

Publication Number Publication Date
FR2181731A1 true FR2181731A1 (en) 1973-12-07

Family

ID=4227821

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7305214A Withdrawn FR2181731A1 (en) 1972-02-15 1973-02-14 Adamantane-1-carboxamidine and derivs - antivirals

Country Status (9)

Country Link
JP (1) JPS4891049A (en)
AU (1) AU5217473A (en)
BE (1) BE795381A (en)
CH (1) CH560678A5 (en)
DD (1) DD105213A5 (en)
DE (1) DE2306784A1 (en)
FR (1) FR2181731A1 (en)
HU (1) HU164968B (en)
NL (1) NL7301841A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726388D0 (en) 1997-12-12 1998-02-11 Cerebrus Ltd Chemical compounds
CN114957621A (en) * 2022-05-13 2022-08-30 嘉应学院 Conjugated polymer containing dinitrogen benzoacenaphthenequinoneimide and preparation method and application thereof

Also Published As

Publication number Publication date
DE2306784A1 (en) 1973-08-30
BE795381A (en) 1973-08-13
JPS4891049A (en) 1973-11-27
HU164968B (en) 1974-05-28
CH560678A5 (en) 1975-04-15
DD105213A5 (en) 1974-04-12
NL7301841A (en) 1973-08-17
AU5217473A (en) 1974-08-15

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Legal Events

Date Code Title Description
ST Notification of lapse