FR2181678B1 - - Google Patents
Info
- Publication number
- FR2181678B1 FR2181678B1 FR7302013A FR7302013A FR2181678B1 FR 2181678 B1 FR2181678 B1 FR 2181678B1 FR 7302013 A FR7302013 A FR 7302013A FR 7302013 A FR7302013 A FR 7302013A FR 2181678 B1 FR2181678 B1 FR 2181678B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB272072A GB1404003A (en) | 1972-01-20 | 1972-01-20 | N-substituted-4-amidopiperidines tetrahydropyridines and pyridines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2181678A1 FR2181678A1 (enExample) | 1973-12-07 |
| FR2181678B1 true FR2181678B1 (enExample) | 1976-09-03 |
Family
ID=9744619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7302013A Expired FR2181678B1 (enExample) | 1972-01-20 | 1973-01-19 |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS59507B2 (enExample) |
| BE (1) | BE794333A (enExample) |
| CA (1) | CA984843A (enExample) |
| CH (2) | CH590840A5 (enExample) |
| DE (1) | DE2302717A1 (enExample) |
| FR (1) | FR2181678B1 (enExample) |
| GB (1) | GB1404003A (enExample) |
| NL (1) | NL180749C (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1542137A (en) * | 1976-03-12 | 1979-03-14 | Wyeth John & Brother Ltd | Process for preparing 3(piperidinoalkyl)indoles |
| US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
| GB1582239A (en) | 1976-12-11 | 1981-01-07 | Wyeth John & Brother Ltd | Piperidin-4-yl ureas and thioureas |
| JPS54160371A (en) * | 1978-06-02 | 1979-12-19 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and hypotensive agents comprising it |
| US4246268A (en) * | 1979-02-09 | 1981-01-20 | Richardson-Merrell Inc. | Neuroleptic-4-(naphthylmethyl)piperidine derivatives |
| US4329348A (en) | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4242347A (en) | 1979-06-18 | 1980-12-30 | Ciba-Geigy Corporation | Hypotensive indolylalkylpiperidyl guanidines and isoureas |
| EP0025111B1 (en) * | 1979-08-10 | 1984-07-25 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
| US4432984A (en) * | 1980-03-27 | 1984-02-21 | Emile Bouchara | Anti-hypertensive benzodioxan derivatives |
| US4410528A (en) * | 1980-05-16 | 1983-10-18 | Kyowa Hakko Kogyo Co., Ltd. | Hypotensive piperidine derivatives |
| DE3025385A1 (de) * | 1980-07-04 | 1982-01-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue tricyclische arylether, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| AU780006B2 (en) | 2000-03-06 | 2005-02-24 | Acadia Pharmaceuticals, Inc. | Azacyclic compounds for use in the treatment of serotonin related diseases |
| EP1461339B1 (en) | 2001-12-28 | 2010-04-28 | Acadia Pharmaceuticals Inc. | Spiroazacyclic compounds as monoamine receptor modulators |
| US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
| US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| AU2003247615B2 (en) | 2002-06-24 | 2007-08-09 | Acadia Pharmaceuticals Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| SI2009000T1 (sl) | 2003-01-16 | 2011-09-30 | Acadia Pharm Inc | Selektivni serotoninski 2A/2C receptorski inverzni agonisti kot terapevtiki za nevrodegenerativne bolezni |
| US7820695B2 (en) | 2004-05-21 | 2010-10-26 | Acadia Pharmaceuticals, Inc. | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US20050261278A1 (en) | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US7790899B2 (en) | 2004-09-27 | 2010-09-07 | Acadia Pharmaceuticals, Inc. | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| KR101260036B1 (ko) | 2004-09-27 | 2013-05-06 | 아카디아 파마슈티칼스 인코포레이티드 | Ｎ－(４－플루오로벤질)－ｎ－(１－메틸피페리딘－４－일)－ｎ＇－(４－(２－메틸프로필옥시)페닐메틸)카르바미드와그의 타르트레이트염 및 결정형의 합성 |
| JP2010522198A (ja) | 2007-03-19 | 2010-07-01 | アカドイア プハルマセウチカルス インコーポレーテッド | ５−ｈｔ２ａインバースアゴニスト及びアンタゴニストの抗精神病薬との併用 |
| US10597363B2 (en) | 2015-07-20 | 2020-03-24 | Acadia Pharmaceuticals Inc. | Methods for preparing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form C |
| WO2017165635A1 (en) | 2016-03-25 | 2017-09-28 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome p450 modulators |
| US10953000B2 (en) | 2016-03-25 | 2021-03-23 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome P450 modulators |
| US11464768B2 (en) | 2016-12-20 | 2022-10-11 | Acadia Pharmaceuticals Inc. | Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis |
| US11135211B2 (en) | 2017-04-28 | 2021-10-05 | Acadia Pharmaceuticals Inc. | Pimavanserin for treating impulse control disorder |
| EP3675827A1 (en) | 2017-08-30 | 2020-07-08 | Acadia Pharmaceuticals Inc. | Formulations of pimavanserin |
-
0
- BE BE794333D patent/BE794333A/xx not_active IP Right Cessation
-
1972
- 1972-01-20 GB GB272072A patent/GB1404003A/en not_active Expired
-
1973
- 1973-01-09 CA CA160,793A patent/CA984843A/en not_active Expired
- 1973-01-19 CH CH82873A patent/CH590840A5/xx not_active IP Right Cessation
- 1973-01-19 JP JP845573A patent/JPS59507B2/ja not_active Expired
- 1973-01-19 CH CH1392476A patent/CH595347A5/xx not_active IP Right Cessation
- 1973-01-19 DE DE19732302717 patent/DE2302717A1/de not_active Ceased
- 1973-01-19 FR FR7302013A patent/FR2181678B1/fr not_active Expired
- 1973-01-19 NL NL7300838A patent/NL180749C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL180749C (nl) | 1987-04-16 |
| CH590840A5 (enExample) | 1977-08-31 |
| CH595347A5 (enExample) | 1978-02-15 |
| GB1404003A (en) | 1975-08-28 |
| CA984843A (en) | 1976-03-02 |
| FR2181678A1 (enExample) | 1973-12-07 |
| JPS4880569A (enExample) | 1973-10-29 |
| DE2302717A1 (de) | 1973-07-26 |
| NL180749B (nl) | 1986-11-17 |
| JPS59507B2 (ja) | 1984-01-07 |
| BE794333A (fr) | 1973-07-19 |
| NL7300838A (enExample) | 1973-07-24 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |