FR2176502A1 - 10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity - Google Patents

10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity

Info

Publication number
FR2176502A1
FR2176502A1 FR7209808A FR7209808A FR2176502A1 FR 2176502 A1 FR2176502 A1 FR 2176502A1 FR 7209808 A FR7209808 A FR 7209808A FR 7209808 A FR7209808 A FR 7209808A FR 2176502 A1 FR2176502 A1 FR 2176502A1
Authority
FR
France
Prior art keywords
spasmolytic
ylalkanoyl
diazabicycloalk
phenothiazines
coronary dilating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7209808A
Other languages
French (fr)
Other versions
FR2176502B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST FARMAKOLOGII AKADEMII
Original Assignee
INST FARMAKOLOGII AKADEMII
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST FARMAKOLOGII AKADEMII filed Critical INST FARMAKOLOGII AKADEMII
Priority to FR7209808A priority Critical patent/FR2176502A1/en
Publication of FR2176502A1 publication Critical patent/FR2176502A1/en
Application granted granted Critical
Publication of FR2176502B1 publication Critical patent/FR2176502B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Cpd. of formula (I) (where X is H, Cl or CF3; n = 1, 2 or 3; m = 3 or 5), and their acid-addn. and quaternary salts are prepd. by reacting a cpd. (II) with a cpd. (III) in an organic solvent, pref. benzene, toluene or xylene, at 50-140 degrees C pref. in the presence of Na2CO3 or NEt3 as acid binder and an iodide catalyst. Cpds. (I) have spasmolytic and coronary dilating activity.
FR7209808A 1972-03-21 1972-03-21 10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity Granted FR2176502A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7209808A FR2176502A1 (en) 1972-03-21 1972-03-21 10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7209808A FR2176502A1 (en) 1972-03-21 1972-03-21 10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity

Publications (2)

Publication Number Publication Date
FR2176502A1 true FR2176502A1 (en) 1973-11-02
FR2176502B1 FR2176502B1 (en) 1975-04-25

Family

ID=9095558

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7209808A Granted FR2176502A1 (en) 1972-03-21 1972-03-21 10-(1,4-diazabicycloalk-1-ylalkanoyl)phenothiazines - - with spasmolytic and coronary dilating activity

Country Status (1)

Country Link
FR (1) FR2176502A1 (en)

Also Published As

Publication number Publication date
FR2176502B1 (en) 1975-04-25

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Legal Events

Date Code Title Description
ST Notification of lapse