FR2152484A2 - Basic esters of cabucinic acid - a yohimbine-type alkaloid derivative with sympatholytic activity - Google Patents
Basic esters of cabucinic acid - a yohimbine-type alkaloid derivative with sympatholytic activityInfo
- Publication number
- FR2152484A2 FR2152484A2 FR7133595A FR7133595A FR2152484A2 FR 2152484 A2 FR2152484 A2 FR 2152484A2 FR 7133595 A FR7133595 A FR 7133595A FR 7133595 A FR7133595 A FR 7133595A FR 2152484 A2 FR2152484 A2 FR 2152484A2
- Authority
- FR
- France
- Prior art keywords
- cabucinic
- acid
- yohimbine
- basic esters
- alkaloid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000002148 esters Chemical class 0.000 title abstract 3
- 150000003797 alkaloid derivatives Chemical class 0.000 title 1
- 230000000948 sympatholitic effect Effects 0.000 title 1
- DTDADHMBRZKXSC-IEGSVRCHSA-N Cabucine Chemical compound C1=C(OC)C=C2C(CCN3C[C@@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 DTDADHMBRZKXSC-IEGSVRCHSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 beta-aminoethyl halide Chemical class 0.000 abstract 1
- XXZJUUFVWAGZEG-UHFFFAOYSA-N cabucine Natural products COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccc(C)cc45)C3CC12 XXZJUUFVWAGZEG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- FVMMOSQBOWPRQW-UHFFFAOYSA-N heterophylline Natural products CC(=O)OC1C2(C)C(OC(=O)C=3C=CC=CC=3)CC(C(O3)(C)C)C(OC(=O)C=4C=NC=CC=4)C32C(C)CC1OC(=O)C1=CC=CN=C1 FVMMOSQBOWPRQW-UHFFFAOYSA-N 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7133595A FR2152484A2 (en) | 1971-09-17 | 1971-09-17 | Basic esters of cabucinic acid - a yohimbine-type alkaloid derivative with sympatholytic activity |
| DE19712147805 DE2147805A1 (de) | 1970-09-30 | 1971-09-24 | Methoxyheteroyohimbin-Abkömmling mit sympatholytischen Eigenschaften, sowie Verfahren für die Gewinnung desselben |
| GB4497671A GB1357166A (en) | 1970-09-30 | 1971-09-27 | Derivatives of methoxyheteroyohimbine with sympatholytical proper ties and preparation methods for producing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7133595A FR2152484A2 (en) | 1971-09-17 | 1971-09-17 | Basic esters of cabucinic acid - a yohimbine-type alkaloid derivative with sympatholytic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2152484A2 true FR2152484A2 (en) | 1973-04-27 |
| FR2152484B2 FR2152484B2 (cs) | 1974-10-18 |
Family
ID=9083132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7133595A Granted FR2152484A2 (en) | 1970-09-30 | 1971-09-17 | Basic esters of cabucinic acid - a yohimbine-type alkaloid derivative with sympatholytic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2152484A2 (cs) |
-
1971
- 1971-09-17 FR FR7133595A patent/FR2152484A2/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2152484B2 (cs) | 1974-10-18 |
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