FR2131888A1 - 2-phenyl-3-(p-toluenesulphonyl)-1,3-oxazines - with hypotensive vasodilator and diuretic activity - Google Patents
2-phenyl-3-(p-toluenesulphonyl)-1,3-oxazines - with hypotensive vasodilator and diuretic activityInfo
- Publication number
- FR2131888A1 FR2131888A1 FR7111514A FR7111514A FR2131888A1 FR 2131888 A1 FR2131888 A1 FR 2131888A1 FR 7111514 A FR7111514 A FR 7111514A FR 7111514 A FR7111514 A FR 7111514A FR 2131888 A1 FR2131888 A1 FR 2131888A1
- Authority
- FR
- France
- Prior art keywords
- hypotensive
- toluenesulphonyl
- oxazines
- vasodilator
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title abstract 2
- 230000001882 diuretic effect Effects 0.000 title abstract 2
- 208000021822 hypotensive Diseases 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- QTFUQWMIPURUJU-UHFFFAOYSA-N 3-(4-methylphenyl)sulfonyl-2-phenyl-2,4-dihydro-1,3-oxazine Chemical class C1(=CC=CC=C1)C1OC=CCN1S(=O)(=O)C1=CC=C(C)C=C1 QTFUQWMIPURUJU-UHFFFAOYSA-N 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 title 1
- 239000003071 vasodilator agent Substances 0.000 title 1
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 1
- WUGQZFFCHPXWKQ-UHFFFAOYSA-N Propanolamine Chemical compound NCCCO WUGQZFFCHPXWKQ-UHFFFAOYSA-N 0.000 abstract 1
- HRDXJKGNWSUIBT-UHFFFAOYSA-N methoxybenzene Chemical group [CH2]OC1=CC=CC=C1 HRDXJKGNWSUIBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
- 125000001064 morpholinomethyl group Chemical group [H]C([H])(*)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H] 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7111514A FR2131888A1 (en) | 1971-04-01 | 1971-04-01 | 2-phenyl-3-(p-toluenesulphonyl)-1,3-oxazines - with hypotensive vasodilator and diuretic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7111514A FR2131888A1 (en) | 1971-04-01 | 1971-04-01 | 2-phenyl-3-(p-toluenesulphonyl)-1,3-oxazines - with hypotensive vasodilator and diuretic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2131888A1 true FR2131888A1 (en) | 1972-11-17 |
| FR2131888B1 FR2131888B1 (https=) | 1974-08-30 |
Family
ID=9074579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7111514A Granted FR2131888A1 (en) | 1971-04-01 | 1971-04-01 | 2-phenyl-3-(p-toluenesulphonyl)-1,3-oxazines - with hypotensive vasodilator and diuretic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2131888A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2215223A1 (en) * | 1973-01-26 | 1974-08-23 | Delalande Sa | 6-morpholinomethyl-1,3-oxazines - with analgesic, hypotensive, analeptic, anticonvulsant, anxiolytic, antidepressant, vasodilator activities etc. |
-
1971
- 1971-04-01 FR FR7111514A patent/FR2131888A1/fr active Granted
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2215223A1 (en) * | 1973-01-26 | 1974-08-23 | Delalande Sa | 6-morpholinomethyl-1,3-oxazines - with analgesic, hypotensive, analeptic, anticonvulsant, anxiolytic, antidepressant, vasodilator activities etc. |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2131888B1 (https=) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |