FR2128071A1 - 5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides - Google Patents

5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides

Info

Publication number
FR2128071A1
FR2128071A1 FR7107287A FR7107287A FR2128071A1 FR 2128071 A1 FR2128071 A1 FR 2128071A1 FR 7107287 A FR7107287 A FR 7107287A FR 7107287 A FR7107287 A FR 7107287A FR 2128071 A1 FR2128071 A1 FR 2128071A1
Authority
FR
France
Prior art keywords
opt
schistosomicides
trichomonacides
amoebicides
thiazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7107287A
Other languages
French (fr)
Other versions
FR2128071B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to FR7107287A priority Critical patent/FR2128071A1/en
Publication of FR2128071A1 publication Critical patent/FR2128071A1/en
Application granted granted Critical
Publication of FR2128071B1 publication Critical patent/FR2128071B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Cpds. of formula: (where R is alkoxy or alkylthio(1-6C) opt. substd. by OH or dialkylamino; benzyloxy; benzylthio; 2-pyridylmethoxy; 2-pyridylmethylthio; or the group -NR1R2 where R1,R2 = 1-6C alkyl opt. substd. by OH or dialkylamino, or R1 and R2 may form a 5- or 6-membered ring with the attached N-atom, opt. substd. by alkyl and opt. contg. another N-, O- or S-atom; A is the group - (CH2)n where n is 2, 3 or 4; -CH(R3)-CH(R4)- where R3,R4 = H, Me, -CH2OH, alkoxycarbonyl (1-4C) provided that both are not H; -CH2.CH(OH).CH2-; -CH2.CO.CH2-; -CH2.CH=N-; -CH2-N(R5)-CH2- where R5 is alkyl (1-6C) opt. substd. by OH or dialkylamino; benzyl; 2-pyridylmethyl).
FR7107287A 1971-03-03 1971-03-03 5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides Granted FR2128071A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7107287A FR2128071A1 (en) 1971-03-03 1971-03-03 5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7107287A FR2128071A1 (en) 1971-03-03 1971-03-03 5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides

Publications (2)

Publication Number Publication Date
FR2128071A1 true FR2128071A1 (en) 1972-10-20
FR2128071B1 FR2128071B1 (en) 1974-08-02

Family

ID=9072817

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7107287A Granted FR2128071A1 (en) 1971-03-03 1971-03-03 5-nitro-2-(n-heterocyclic)thiazoles - as schistosomicides amoebicides,trichomonacides and bactericides

Country Status (1)

Country Link
FR (1) FR2128071A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501009A (en) * 1967-11-16 1970-12-31 Ciba Geigy Ag 1-(5-nitro-2-thiazolyl)-2-oxo-imidazolidines - prepn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH501009A (en) * 1967-11-16 1970-12-31 Ciba Geigy Ag 1-(5-nitro-2-thiazolyl)-2-oxo-imidazolidines - prepn

Also Published As

Publication number Publication date
FR2128071B1 (en) 1974-08-02

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