FR2118191A1 - (3-amino-2-hydroxypropoxy) coumarins - with cardiac and circulatory acitivty - Google Patents

(3-amino-2-hydroxypropoxy) coumarins - with cardiac and circulatory acitivty

Info

Publication number
FR2118191A1
FR2118191A1 FR7145696A FR7145696A FR2118191A1 FR 2118191 A1 FR2118191 A1 FR 2118191A1 FR 7145696 A FR7145696 A FR 7145696A FR 7145696 A FR7145696 A FR 7145696A FR 2118191 A1 FR2118191 A1 FR 2118191A1
Authority
FR
France
Prior art keywords
alkyl
cardiac
amino
circulatory
acitivty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7145696A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr L Zambeletti SpA
Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr L Zambeletti SpA filed Critical Dr L Zambeletti SpA
Publication of FR2118191A1 publication Critical patent/FR2118191A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Abstract

Cpds. of formula: (where R is 1-4C alkyl, 2-4C alkenyl or aryl or aryl-(1-3C)-alkyl opt. ring substd. by 1-4C alkyl or alkoxy or halogen; A is NH2, mono- or di(1-6C alkyl) amino, mono- or di(1-4C hydroxylalkyl)-aminon, pyrrolidino, piperidino, morpholino or piperazino 4-substd. by 1-4C alkyl, 2-hydroxyethyl, 2-(hydroxyethoxy)-ethyl or where R2 is 1-4C alkyl or alkoxy or halogen, and n = 0-3; R1 is H, halogen or 1-4C alkyl) have cardiac and circulatory activity. They may be prepd. by reacting MO-substd. coumarin (where M = H or a metal atom) with ACH2CHOHCH2Hal.
FR7145696A 1970-12-19 1971-12-20 (3-amino-2-hydroxypropoxy) coumarins - with cardiac and circulatory acitivty Withdrawn FR2118191A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3329270 1970-12-19

Publications (1)

Publication Number Publication Date
FR2118191A1 true FR2118191A1 (en) 1972-07-28

Family

ID=11237088

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7145696A Withdrawn FR2118191A1 (en) 1970-12-19 1971-12-20 (3-amino-2-hydroxypropoxy) coumarins - with cardiac and circulatory acitivty

Country Status (2)

Country Link
DE (1) DE2162721A1 (en)
FR (1) FR2118191A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313034A1 (en) * 1975-06-03 1976-12-31 Beecham Group Ltd POLYCYCLIC COMPOUNDS
EP0013894A1 (en) * 1979-01-15 1980-08-06 Roche Diagnostics GmbH Arylethers, process for their preparation and medicines containing them
EP3133066A1 (en) * 2015-08-21 2017-02-22 Merck Patent GmbH Hydrophilic compounds for optically active devices
US11078177B2 (en) 2015-08-21 2021-08-03 Merck Patent Gmbh Compounds for optically active devices
US11702396B2 (en) 2017-02-15 2023-07-18 Johnson & Johnson Surgical Vision, Inc. Hydrophobic compounds for optically active devices
US11753387B2 (en) 2017-02-15 2023-09-12 Johnson & Johnson Surgical Vision, Inc. Compounds for optically active devices

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113816944B (en) * 2020-06-20 2023-06-27 中山大学 Anti-filovirus compounds and uses thereof

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313034A1 (en) * 1975-06-03 1976-12-31 Beecham Group Ltd POLYCYCLIC COMPOUNDS
EP0013894A1 (en) * 1979-01-15 1980-08-06 Roche Diagnostics GmbH Arylethers, process for their preparation and medicines containing them
US10723713B2 (en) 2015-08-21 2020-07-28 Merck Patent Gmbh Hydrophilic compounds for optically active devices
WO2017032444A1 (en) * 2015-08-21 2017-03-02 Merck Patent Gmbh Hydrophilic compounds for optically active devices
CN107922370A (en) * 2015-08-21 2018-04-17 默克专利股份有限公司 Hydrophilic compounds for optical activity apparatus
JP2018525444A (en) * 2015-08-21 2018-09-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Hydrophilic compounds for optically active devices
EP3133066A1 (en) * 2015-08-21 2017-02-22 Merck Patent GmbH Hydrophilic compounds for optically active devices
US11078177B2 (en) 2015-08-21 2021-08-03 Merck Patent Gmbh Compounds for optically active devices
US11111226B2 (en) 2015-08-21 2021-09-07 Merck Patent Gmbh Hydrophilic compounds for optically active devices
CN107922370B (en) * 2015-08-21 2021-12-10 默克专利股份有限公司 Hydrophilic compounds for optically active devices
US11958819B2 (en) 2015-08-21 2024-04-16 Johnson & Johnson Surgical Vision, Inc. Compounds for optically active devices
US11702396B2 (en) 2017-02-15 2023-07-18 Johnson & Johnson Surgical Vision, Inc. Hydrophobic compounds for optically active devices
US11753387B2 (en) 2017-02-15 2023-09-12 Johnson & Johnson Surgical Vision, Inc. Compounds for optically active devices

Also Published As

Publication number Publication date
DE2162721A1 (en) 1972-06-22

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Legal Events

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