FR2112098A1 - Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity - Google Patents
Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activityInfo
- Publication number
- FR2112098A1 FR2112098A1 FR7039458A FR7039458A FR2112098A1 FR 2112098 A1 FR2112098 A1 FR 2112098A1 FR 7039458 A FR7039458 A FR 7039458A FR 7039458 A FR7039458 A FR 7039458A FR 2112098 A1 FR2112098 A1 FR 2112098A1
- Authority
- FR
- France
- Prior art keywords
- glucosides
- hypocholesterolaemic
- vascular system
- protective activity
- acid esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930182478 glucoside Natural products 0.000 title abstract 3
- 150000008131 glucosides Chemical class 0.000 title abstract 3
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical class OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000871 hypocholesterolemic effect Effects 0.000 title abstract 2
- 230000001681 protective effect Effects 0.000 title abstract 2
- 230000002792 vascular Effects 0.000 title abstract 2
- FDHNLHLOJLLXDH-JIYHLSBYSA-N (e)-3-(3-hydroxy-4-methoxyphenyl)-1-[2-hydroxy-6-methoxy-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]prop-2-en-1-one Chemical compound C1=C(O)C(OC)=CC=C1\C=C\C(=O)C(C(=C1)OC)=C(O)C=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)O1 FDHNLHLOJLLXDH-JIYHLSBYSA-N 0.000 abstract 3
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- PLXMOAALOJOTIY-FPTXNFDTSA-N Aesculin Natural products OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1Oc2cc3C=CC(=O)Oc3cc2O PLXMOAALOJOTIY-FPTXNFDTSA-N 0.000 abstract 1
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical compound CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 abstract 1
- 229960001214 clofibrate Drugs 0.000 abstract 1
- XHCADAYNFIFUHF-TVKJYDDYSA-N esculin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC2=C1OC(=O)C=C2 XHCADAYNFIFUHF-TVKJYDDYSA-N 0.000 abstract 1
- 229940076640 hesperidin methylchalcone Drugs 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229960004555 rutoside Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7039458A FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7039458A FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2112098A1 true FR2112098A1 (en) | 1972-06-16 |
| FR2112098B1 FR2112098B1 (OSRAM) | 1974-04-12 |
Family
ID=9063664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7039458A Granted FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2112098A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0654479A3 (en) * | 1993-11-15 | 1995-09-13 | Kureha Chemical Ind Co Ltd | Esculetin derivatives, process for their preparation and their use as pharmaceutical compositions. |
-
1970
- 1970-11-03 FR FR7039458A patent/FR2112098A1/fr active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0654479A3 (en) * | 1993-11-15 | 1995-09-13 | Kureha Chemical Ind Co Ltd | Esculetin derivatives, process for their preparation and their use as pharmaceutical compositions. |
| US5736522A (en) * | 1993-11-15 | 1998-04-07 | Kureha Chemical Industry Co., Ltd. | Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition |
| CN1053193C (zh) * | 1993-11-15 | 2000-06-07 | 吴羽化学工业株式会社 | 七叶亭衍生物和其制造方法与用途及其医药组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2112098B1 (OSRAM) | 1974-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |