FR2112098A1 - Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity - Google Patents
Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activityInfo
- Publication number
- FR2112098A1 FR2112098A1 FR7039458A FR7039458A FR2112098A1 FR 2112098 A1 FR2112098 A1 FR 2112098A1 FR 7039458 A FR7039458 A FR 7039458A FR 7039458 A FR7039458 A FR 7039458A FR 2112098 A1 FR2112098 A1 FR 2112098A1
- Authority
- FR
- France
- Prior art keywords
- glucosides
- hypocholesterolaemic
- vascular system
- protective activity
- acid esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
The 2-p-chlorophenoxy-2-methylpropionate esters of esculoside (I), rutoside (II) and hesperidin methyl chalcone (III) are claimed. The penta-ester of (I), deca-ester of (II) and poly-ester of (III) combined the hypocholesterolaemic activity of clofibrate with the vascular system protective activity of the glucosides. The esters are prepd. by adding the acid chloride to a soln. of the glucoside in pyridine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7039458A FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7039458A FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2112098A1 true FR2112098A1 (en) | 1972-06-16 |
FR2112098B1 FR2112098B1 (en) | 1974-04-12 |
Family
ID=9063664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7039458A Granted FR2112098A1 (en) | 1970-11-03 | 1970-11-03 | Clofibric acid esters of glucosides - with hypocholesterolaemic and vascular system protective activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2112098A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0654479A2 (en) * | 1993-11-15 | 1995-05-24 | Kureha Chemical Industry Co., Ltd. | Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition |
-
1970
- 1970-11-03 FR FR7039458A patent/FR2112098A1/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0654479A2 (en) * | 1993-11-15 | 1995-05-24 | Kureha Chemical Industry Co., Ltd. | Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition |
EP0654479A3 (en) * | 1993-11-15 | 1995-09-13 | Kureha Chemical Ind Co Ltd | Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition. |
US5736522A (en) * | 1993-11-15 | 1998-04-07 | Kureha Chemical Industry Co., Ltd. | Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition |
CN1053193C (en) * | 1993-11-15 | 2000-06-07 | 吴羽化学工业株式会社 | Esculetin derivatives, process for manufacture and use thereof, and pharmaceutical composition |
Also Published As
Publication number | Publication date |
---|---|
FR2112098B1 (en) | 1974-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |