FR2088086A1 - 2-nitro-4,5-dihydro-4 oxo furo (2,3-d) pyridazines - with broad spectrum antibacterial activity - Google Patents
2-nitro-4,5-dihydro-4 oxo furo (2,3-d) pyridazines - with broad spectrum antibacterial activityInfo
- Publication number
- FR2088086A1 FR2088086A1 FR7017831A FR7017831A FR2088086A1 FR 2088086 A1 FR2088086 A1 FR 2088086A1 FR 7017831 A FR7017831 A FR 7017831A FR 7017831 A FR7017831 A FR 7017831A FR 2088086 A1 FR2088086 A1 FR 2088086A1
- Authority
- FR
- France
- Prior art keywords
- pyridazines
- dihydro
- nitro
- antibacterial activity
- broad spectrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BNLUWIBALCIAQE-UHFFFAOYSA-N [N+](=O)([O-])C1=CC2=C(C=NNC2=O)O1 Chemical class [N+](=O)([O-])C1=CC2=C(C=NNC2=O)O1 BNLUWIBALCIAQE-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 230000004224 protection Effects 0.000 abstract 3
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 abstract 2
- 241000699670 Mus sp. Species 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 241001467018 Typhis Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- XMEVHPAGJVLHIG-FMZCEJRJSA-N chembl454950 Chemical compound [Cl-].C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H]([NH+](C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O XMEVHPAGJVLHIG-FMZCEJRJSA-N 0.000 abstract 1
- MOBPCMQBARMUHY-UHFFFAOYSA-N ethyl 2-formylfuran-3-carboxylate Chemical compound CCOC(=O)C=1C=COC=1C=O MOBPCMQBARMUHY-UHFFFAOYSA-N 0.000 abstract 1
- 150000002429 hydrazines Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 235000010333 potassium nitrate Nutrition 0.000 abstract 1
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 229960004989 tetracycline hydrochloride Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7017831A FR2088086A1 (en) | 1970-05-15 | 1970-05-15 | 2-nitro-4,5-dihydro-4 oxo furo (2,3-d) pyridazines - with broad spectrum antibacterial activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7017831A FR2088086A1 (en) | 1970-05-15 | 1970-05-15 | 2-nitro-4,5-dihydro-4 oxo furo (2,3-d) pyridazines - with broad spectrum antibacterial activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2088086A1 true FR2088086A1 (en) | 1972-01-07 |
| FR2088086B1 FR2088086B1 (enExample) | 1973-04-06 |
Family
ID=9055601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7017831A Granted FR2088086A1 (en) | 1970-05-15 | 1970-05-15 | 2-nitro-4,5-dihydro-4 oxo furo (2,3-d) pyridazines - with broad spectrum antibacterial activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2088086A1 (enExample) |
-
1970
- 1970-05-15 FR FR7017831A patent/FR2088086A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2088086B1 (enExample) | 1973-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |