FR2081398A1 - Prostaglandin intermediates - Google Patents
Prostaglandin intermediatesInfo
- Publication number
- FR2081398A1 FR2081398A1 FR7046615A FR7046615A FR2081398A1 FR 2081398 A1 FR2081398 A1 FR 2081398A1 FR 7046615 A FR7046615 A FR 7046615A FR 7046615 A FR7046615 A FR 7046615A FR 2081398 A1 FR2081398 A1 FR 2081398A1
- Authority
- FR
- France
- Prior art keywords
- deriv
- co2h
- cho
- intermediates
- prostaglandin intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 3
- 239000000543 intermediate Substances 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 238000005698 Diels-Alder reaction Methods 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- ZSWFCLXCOIISFI-UHFFFAOYSA-N cyclopentadiene Chemical compound C1C=CC=C1 ZSWFCLXCOIISFI-UHFFFAOYSA-N 0.000 abstract 1
- 230000004992 fission Effects 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Cpds. of formulae (I and II): where R' = (CH2)nX, X = CO2H or a deriv, hal or OH, n = 1-7, Y' = CHO or CO2H or a deriv. and Z' = CHO, CO2H or a deriv. CH2OH, CH3CO, CH3CO2 and/or OH, are intermediates for prostaglandins. (II) are prepd. by Diels Alder condensation of cyclopentandiene and R'CH=CHY', and are converted to (I) by oxidative fission followed by appropriate modification of Z'.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7046615A FR2081398A1 (en) | 1970-12-24 | 1970-12-24 | Prostaglandin intermediates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7046615A FR2081398A1 (en) | 1970-12-24 | 1970-12-24 | Prostaglandin intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2081398A1 true FR2081398A1 (en) | 1971-12-03 |
Family
ID=9066339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7046615A Pending FR2081398A1 (en) | 1970-12-24 | 1970-12-24 | Prostaglandin intermediates |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2081398A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2206303A1 (en) * | 1972-11-10 | 1974-06-07 | Ici Ltd |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3483102A (en) * | 1964-05-06 | 1969-12-09 | Union Carbide Corp | Photosensitized cycloadding process |
FR2070680A1 (en) * | 1969-09-09 | 1971-09-17 | Sumitomo Chemical Cy Inc |
-
1970
- 1970-12-24 FR FR7046615A patent/FR2081398A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3483102A (en) * | 1964-05-06 | 1969-12-09 | Union Carbide Corp | Photosensitized cycloadding process |
FR2070680A1 (en) * | 1969-09-09 | 1971-09-17 | Sumitomo Chemical Cy Inc |
Non-Patent Citations (2)
Title |
---|
JOURNAL OF ORGANIC CHEMISTRY, vol. 35, no. 7, juillet 1970, pages 2314-2318 * |
ORGANIC SYNTHESIS, vol. 1, 1957, pages 330-331, Reinhold Publishing Corporation, New York, USA * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2206303A1 (en) * | 1972-11-10 | 1974-06-07 | Ici Ltd |
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