FR2068396A1 - adamantyl thiadiazoles. antifungals - Google Patents

adamantyl thiadiazoles. antifungals

Info

Publication number
FR2068396A1
FR2068396A1 FR6933646A FR6933646A FR2068396A1 FR 2068396 A1 FR2068396 A1 FR 2068396A1 FR 6933646 A FR6933646 A FR 6933646A FR 6933646 A FR6933646 A FR 6933646A FR 2068396 A1 FR2068396 A1 FR 2068396A1
Authority
FR
France
Prior art keywords
opt
adamantyl
lower alkyl
substd
contng
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6933646A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Priority to FR6933646A priority Critical patent/FR2068396A1/en
Publication of FR2068396A1 publication Critical patent/FR2068396A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/12—Saturated polycyclic compounds
    • C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
    • C07C61/135—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having three rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Adamantyl thiadiazole derivs. I, and acid addn. salts R=H, hal, trihalomethyl, lower alkyl, lower alkoxy, Ph, NH2, lower alkanoylamino, mono- or di-lower alkylamino B=Basic N-contng. radical NR1R2, where R1 and R2=H, opt. substd. adamantyl, lower alkyl opt. substd. by OH, Ph,N-(lower alkyl)phenyl; cyclo-lower alkyl, alkanoyl; or NR1R2 may be a 5-7 membered monocyclic heterocyclic ring opt. contng. additional heteroatoms, and opt. substd. by e.g. alkyl Preferred cpds. have R=H and B=NMe2. I are topical fungal disinfectants against e.g. Aspergillus niger, Chaetomium globosum. I are applied, as a 1% cream or ointment, 2-4 times daily.
FR6933646A 1969-10-02 1969-10-02 adamantyl thiadiazoles. antifungals Withdrawn FR2068396A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6933646A FR2068396A1 (en) 1969-10-02 1969-10-02 adamantyl thiadiazoles. antifungals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6933646A FR2068396A1 (en) 1969-10-02 1969-10-02 adamantyl thiadiazoles. antifungals

Publications (1)

Publication Number Publication Date
FR2068396A1 true FR2068396A1 (en) 1971-08-27

Family

ID=9040938

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6933646A Withdrawn FR2068396A1 (en) 1969-10-02 1969-10-02 adamantyl thiadiazoles. antifungals

Country Status (1)

Country Link
FR (1) FR2068396A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6815221A (en) * 1967-10-26 1969-04-29

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6815221A (en) * 1967-10-26 1969-04-29

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
(LA *REVUE"CHEMICAL ABSTACTS"71 1969 9T415UCITE"COLLECT.CZECH.CHEM.COMMUN.1969 34 B 2278-87) *
LA REVUE"CHEMICAL ABSTACTS"71 1969 9T415UCITE"COLLECT.CZECH.CHEM.COMMUN.1969 34 B 2278-87) *

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Legal Events

Date Code Title Description
ST Notification of lapse