FR2035756A1 - N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine - Google Patents

N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine

Info

Publication number
FR2035756A1
FR2035756A1 FR6904681A FR6904681A FR2035756A1 FR 2035756 A1 FR2035756 A1 FR 2035756A1 FR 6904681 A FR6904681 A FR 6904681A FR 6904681 A FR6904681 A FR 6904681A FR 2035756 A1 FR2035756 A1 FR 2035756A1
Authority
FR
France
Prior art keywords
guanidine
aminobenzenesulphonyl
dimethyloxazolyl
tract
title cpd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6904681A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NORDLUFT GERAETEBAU GmbH
Nordmark Werke GmbH
Original Assignee
NORDLUFT GERAETEBAU GmbH
Nordmark Werke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NORDLUFT GERAETEBAU GmbH, Nordmark Werke GmbH filed Critical NORDLUFT GERAETEBAU GmbH
Priority to FR6904681A priority Critical patent/FR2035756A1/en
Publication of FR2035756A1 publication Critical patent/FR2035756A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48—Nitrogen atoms not forming part of a nitro radical
    • C07D263/50—Benzene-sulfonamido oxazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-(p-Aminobenzenesulphonyl)-3-(4,5-dimethyl-2-oxazolyl)-guanidine Title cpd. of formula (I) is prepd. by reacting a 1-benzenesulphonyl-3-cyano-guanidine (II) (where X is NH2 or a substituent convertible into NH2, e.f. acylamino, azo or NO2) with acetoin and, when X is not = NH2, converting X into NH2 in a known manner. Title cpd. has excellent chemotherapeutic, esp. bacteriostatic properties and, because of low resorption from the GI tract, is useful for treating GI tract infections.
FR6904681A 1969-02-24 1969-02-24 N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine Withdrawn FR2035756A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6904681A FR2035756A1 (en) 1969-02-24 1969-02-24 N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6904681A FR2035756A1 (en) 1969-02-24 1969-02-24 N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine

Publications (1)

Publication Number Publication Date
FR2035756A1 true FR2035756A1 (en) 1970-12-24

Family

ID=9029520

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6904681A Withdrawn FR2035756A1 (en) 1969-02-24 1969-02-24 N-aminobenzenesulphonyl-n-2-(dimethyloxazolyl)guanidine

Country Status (1)

Country Link
FR (1) FR2035756A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1261865A (en) * 1956-07-02 1961-05-26 Nordmark Werke Gmbh Process for the preparation of p-aminobenzenesulfonyl-2-amino-4.5-dimethyl-oxazole and its salts
FR1306621A (en) * 1960-02-01 1962-10-19 Nordmark Werke Ges M B H Process for preparing 2-aminooxazoles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1261865A (en) * 1956-07-02 1961-05-26 Nordmark Werke Gmbh Process for the preparation of p-aminobenzenesulfonyl-2-amino-4.5-dimethyl-oxazole and its salts
FR1306621A (en) * 1960-02-01 1962-10-19 Nordmark Werke Ges M B H Process for preparing 2-aminooxazoles

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Legal Events

Date Code Title Description
ST Notification of lapse