FR2017311A1 - Medicament preparation for controlled release - Google Patents

Medicament preparation for controlled release

Info

Publication number
FR2017311A1
FR2017311A1 FR6930103A FR6930103A FR2017311A1 FR 2017311 A1 FR2017311 A1 FR 2017311A1 FR 6930103 A FR6930103 A FR 6930103A FR 6930103 A FR6930103 A FR 6930103A FR 2017311 A1 FR2017311 A1 FR 2017311A1
Authority
FR
France
Prior art keywords
polymer
styrene
controlled release
basic
medicament preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6930103A
Other languages
French (fr)
Other versions
FR2017311B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2017311A1 publication Critical patent/FR2017311A1/en
Application granted granted Critical
Publication of FR2017311B1 publication Critical patent/FR2017311B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin

Abstract

Consist of a basic active drug adsorbed on colloidal particles of a physiologically harmless polymer which is hydratable in the gastro-intenstinal tract. The polymer is the result of emulsion polymerisation of (a) at least one of acrylic methacrylic, crotonic, itaconic, or maleic acids or maleic esters or anhydride or sulphonated or phosphorylated styrene and (b) at least one of vinyl chloride, acetate, propionate or ethers, hydroxyethyl-methacrylate, acrylonitrile, ethylene-, styrene-, or lower alkyl acrylates or methacrylates. The incorporated drug should contain a basic N-group when the polymer has an acid function and vice versa. The prepn. may be in solid or liquid form.
FR6930103A 1968-09-03 1969-09-03 Medicament preparation for controlled release Granted FR2017311A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75714368A 1968-09-03 1968-09-03
US85066369A 1969-08-15 1969-08-15

Publications (2)

Publication Number Publication Date
FR2017311A1 true FR2017311A1 (en) 1970-05-22
FR2017311B1 FR2017311B1 (en) 1973-01-12

Family

ID=27116338

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6930103A Granted FR2017311A1 (en) 1968-09-03 1969-09-03 Medicament preparation for controlled release

Country Status (4)

Country Link
CA (1) CA927282A (en)
DE (1) DE1944693C3 (en)
FR (1) FR2017311A1 (en)
MY (1) MY7300483A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE28316E (en) * 1968-09-03 1975-01-21 Entrapment compositions and processes
DE2732335C2 (en) * 1976-07-27 1983-01-20 Sandoz-Patent-GmbH, 7850 Lörrach Tablet for the enteral administration of indolyloxyalkanolamine derivatives
CA1086226A (en) * 1976-11-26 1980-09-23 Yegnaswami Raghunathan Ion exchange resin prolonged release pharmaceutical preparations
DE3930733A1 (en) * 1989-09-14 1991-03-28 Roehm Gmbh METHOD FOR PRODUCING A COMPLEX MEDICINAL PRODUCT
NL9002336A (en) * 1990-10-24 1992-05-18 Leuven K U Res & Dev COATING OR MATRIX MATERIAL FOR MEDICINES.
ATE374044T1 (en) * 2004-04-05 2007-10-15 Basf Ag POLYMER PARTICLES CONTAINING ACTIVE INGREDIENTS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990332A (en) * 1958-04-02 1961-06-27 Wallace & Tiernan Inc Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith
FR1468716A (en) * 1964-06-19 1967-02-10 Ciba Geigy Process for preparing drugs in the form of beads

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990332A (en) * 1958-04-02 1961-06-27 Wallace & Tiernan Inc Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith
FR1468716A (en) * 1964-06-19 1967-02-10 Ciba Geigy Process for preparing drugs in the form of beads

Also Published As

Publication number Publication date
DE1944693A1 (en) 1970-04-30
FR2017311B1 (en) 1973-01-12
MY7300483A (en) 1973-12-31
DE1944693B2 (en) 1977-12-22
DE1944693C3 (en) 1978-08-24
CA927282A (en) 1973-05-29

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Legal Events

Date Code Title Description
ST Notification of lapse