FR2007444B1 - - Google Patents

Info

Publication number
FR2007444B1
FR2007444B1 FR696911222A FR6911222A FR2007444B1 FR 2007444 B1 FR2007444 B1 FR 2007444B1 FR 696911222 A FR696911222 A FR 696911222A FR 6911222 A FR6911222 A FR 6911222A FR 2007444 B1 FR2007444 B1 FR 2007444B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR696911222A
Other versions
FR2007444A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck et Cie
Merck and Co Inc
Original Assignee
Merck et Cie
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck et Cie, Merck and Co Inc filed Critical Merck et Cie
Publication of FR2007444A1 publication Critical patent/FR2007444A1/fr
Application granted granted Critical
Publication of FR2007444B1 publication Critical patent/FR2007444B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR696911222A 1968-04-12 1969-04-11 Expired FR2007444B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72106568A 1968-04-12 1968-04-12

Publications (2)

Publication Number Publication Date
FR2007444A1 FR2007444A1 (fr) 1970-01-09
FR2007444B1 true FR2007444B1 (fr) 1973-01-12

Family

ID=24896392

Family Applications (1)

Application Number Title Priority Date Filing Date
FR696911222A Expired FR2007444B1 (fr) 1968-04-12 1969-04-11

Country Status (5)

Country Link
US (1) US3461123A (fr)
DE (1) DE1918550A1 (fr)
FR (1) FR2007444B1 (fr)
GB (1) GB1219255A (fr)
NL (1) NL6904503A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541093A (en) * 1968-08-22 1970-11-17 Merck & Co Inc Process for the preparation of 1h-imidazo(4,5-b)pyrazine-2-ones
DE3029871C2 (de) 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) * 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
AU2013363218B2 (en) 2012-12-17 2018-03-15 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
US3461123A (en) 1969-08-12
FR2007444A1 (fr) 1970-01-09
NL6904503A (fr) 1969-10-14
GB1219255A (en) 1971-01-13
DE1918550A1 (de) 1970-06-11

Similar Documents

Publication Publication Date Title
AU428130B2 (fr)
AU2374870A (fr)
AU5184069A (fr)
AU6168869A (fr)
AU6171569A (fr)
AU429879B2 (fr)
AU416157B2 (fr)
AU2581067A (fr)
AU4811568A (fr)
AU421558B1 (fr)
AU3789668A (fr)
AU4744468A (fr)
AU3224368A (fr)
AU2580267A (fr)
AU479393A (fr)
BE708888A (fr)
AU4503667A (fr)
AU4558658A (fr)
AU463027A (fr)
AU4270368A (fr)
BE727789A (fr)
AU479894A (fr)
AU4224469A (fr)
AU3083868A (fr)
AU2889368A (fr)

Legal Events

Date Code Title Description
ST Notification of lapse