FR2004651A1 - (A) Cmpds. of general formula (I): R = NH2, omega-carboxy- (1-6C) alkylamino, omega-aminocarboxy (1-6C) alkylamino, omega-carbonamido-(1-6C) alkylamino, - Google Patents

(A) Cmpds. of general formula (I): R = NH2, omega-carboxy- (1-6C) alkylamino, omega-aminocarboxy (1-6C) alkylamino, omega-carbonamido-(1-6C) alkylamino,

Info

Publication number
FR2004651A1
FR2004651A1 FR6908542A FR6908542A FR2004651A1 FR 2004651 A1 FR2004651 A1 FR 2004651A1 FR 6908542 A FR6908542 A FR 6908542A FR 6908542 A FR6908542 A FR 6908542A FR 2004651 A1 FR2004651 A1 FR 2004651A1
Authority
FR
France
Prior art keywords
omega
alkylamino
carbonamido
alkyl
cmpds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR6908542A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6120668A external-priority patent/GB1237228A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2004651A1 publication Critical patent/FR2004651A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F38/00—Adaptations of transformers or inductances for specific applications or functions
    • H01F38/20—Instruments transformers
    • H01F38/22—Instruments transformers for single phase ac
    • H01F38/28—Current transformers

Abstract

(A) Cmpds. of general formula (I): R = NH2, omega-carboxy- (1-6C) alkylamino, omega-aminocarboxy (1-6C) alkylamino, omega-carbonamido-(1-6C) alkylamino, omega-amino- omega-carbonamido-(1-6C) alkylamino, or NR1R2, where R1= (1-17C) alkyl, PhCH2, PhCH2CH2, cyclohexyl, (2-4C) hydroxyalkyl, omega-amino(1-6C) alkyl, omega-(1-6C)-alkylamino- (1-6C)-alkyl, or omega-((1-6C) alkyl)2 amino (1-6C) alkyl and R2 = H or R1 or NR1R2 = piperidino, pyrrolidino, morpholino, piperazino, N-methylpiperazino, 2,6-dimethylmorpholino, N-(beta-hydroxyethyl) piperazino or a gp. of formula: (B) Salts of (I). Antibiotics. Dose 0.05-1.0 g. (par., i.m., or i.v.). (a) I have higher solubility in H2O than (III) (b) I do not readily hydrolyse and ppt. over the pH range 3-8.
FR6908542A 1968-03-25 1969-03-24 (A) Cmpds. of general formula (I): R = NH2, omega-carboxy- (1-6C) alkylamino, omega-aminocarboxy (1-6C) alkylamino, omega-carbonamido-(1-6C) alkylamino, Pending FR2004651A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71558968A 1968-03-25 1968-03-25
GB6120668A GB1237228A (en) 1968-03-25 1968-12-23 MANNICH BASES OF alpha-6-DEOXY-5-OXYTETRACYCLINE

Publications (1)

Publication Number Publication Date
FR2004651A1 true FR2004651A1 (en) 1969-11-28

Family

ID=26267844

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6908542A Pending FR2004651A1 (en) 1968-03-25 1969-03-24 (A) Cmpds. of general formula (I): R = NH2, omega-carboxy- (1-6C) alkylamino, omega-aminocarboxy (1-6C) alkylamino, omega-carbonamido-(1-6C) alkylamino,

Country Status (5)

Country Link
BE (1) BE730315A (en)
CH (1) CH495955A (en)
DE (1) DE1914194A1 (en)
FR (1) FR2004651A1 (en)
NL (1) NL6904515A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2784847B2 (en) * 1994-02-17 1998-08-06 ファイザー インク． 9- (Substituted amino) -alpha-6-deoxy-5-oxytetracycline derivatives, their preparation and their use as antibiotics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023117A1 (en) * 1979-07-11 1981-01-28 Sulzer Bros (Uk) Ltd. Improvements in or relating to machine drive systems
DE3230816A1 (en) * 1982-08-19 1984-02-23 Elwaplastic Maschinenbau Gmbh Process and device for the continuous processing of thermoplastic web material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023117A1 (en) * 1979-07-11 1981-01-28 Sulzer Bros (Uk) Ltd. Improvements in or relating to machine drive systems
DE3230816A1 (en) * 1982-08-19 1984-02-23 Elwaplastic Maschinenbau Gmbh Process and device for the continuous processing of thermoplastic web material

Also Published As

Publication number Publication date
DE1914194A1 (en) 1969-10-02
BE730315A (en) 1969-09-24
NL6904515A (en) 1969-09-29
CH495955A (en) 1970-09-15

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