FR2000114A1 - STABLE AQUEOUS SOLUTION FOR INJECTION OF GLUCAGON, AND PROCESS FOR ITS PREPARATION - Google Patents

STABLE AQUEOUS SOLUTION FOR INJECTION OF GLUCAGON, AND PROCESS FOR ITS PREPARATION

Info

Publication number
FR2000114A1
FR2000114A1 FR6900222A FR6900222A FR2000114A1 FR 2000114 A1 FR2000114 A1 FR 2000114A1 FR 6900222 A FR6900222 A FR 6900222A FR 6900222 A FR6900222 A FR 6900222A FR 2000114 A1 FR2000114 A1 FR 2000114A1
Authority
FR
France
Prior art keywords
glucagon
injection
preparation
aqueous solution
stable aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6900222A
Other languages
French (fr)
Inventor
Jan Markussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Terapeutisk Laboratorium AS
Original Assignee
Novo Terapeutisk Laboratorium AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Laboratorium AS filed Critical Novo Terapeutisk Laboratorium AS
Publication of FR2000114A1 publication Critical patent/FR2000114A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR6900222A 1968-01-10 1969-01-09 STABLE AQUEOUS SOLUTION FOR INJECTION OF GLUCAGON, AND PROCESS FOR ITS PREPARATION Withdrawn FR2000114A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0536/68A GB1202607A (en) 1968-01-10 1968-01-10 Improvements in or relating to stable glucagon solutions and their preparation

Publications (1)

Publication Number Publication Date
FR2000114A1 true FR2000114A1 (en) 1969-08-29

Family

ID=9723689

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6900222A Withdrawn FR2000114A1 (en) 1968-01-10 1969-01-09 STABLE AQUEOUS SOLUTION FOR INJECTION OF GLUCAGON, AND PROCESS FOR ITS PREPARATION

Country Status (7)

Country Link
AT (1) AT283600B (en)
BE (1) BE726681A (en)
DE (1) DE1900367A1 (en)
FR (1) FR2000114A1 (en)
GB (1) GB1202607A (en)
IT (1) IT974528B (en)
NL (1) NL6900460A (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
US7235627B2 (en) 1996-08-30 2007-06-26 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6384016B1 (en) * 1998-03-13 2002-05-07 Novo Nordisk A/S Stabilized aqueous peptide solutions
JP4072319B2 (en) * 1998-03-13 2008-04-09 ノヴォ ノルディスク アクティーゼルスカブ Stabilized water-soluble peptide solution
US9610329B2 (en) 2009-10-22 2017-04-04 Albireo Pharma, Inc. Stabilized glucagon solutions
WO2011049713A2 (en) 2009-10-22 2011-04-28 Biodel Inc. Stabilized glucagon solutions
WO2012059762A1 (en) 2010-11-03 2012-05-10 Arecor Limited Novel composition comprising glucagon
BR112014016889A8 (en) 2012-01-09 2017-07-04 Adocia composition in the form of an aqueous injectable solution ph is comprised between 6.0 and 8.0 and unit dose formulation with ph comprised between 7 and 7.8
US20150314003A2 (en) 2012-08-09 2015-11-05 Adocia Injectable solution at ph 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer
FR3052071B1 (en) * 2016-06-07 2018-09-07 Adocia COMPOSITIONS IN THE FORM OF AQUEOUS INJECTABLE SOLUTION COMPRISING GLUCAGON AND A CO-POLYAMINOACID
FR3061660B1 (en) * 2017-01-10 2019-05-31 Adocia COMPOSITIONS IN THE FORM OF AN INJECTION AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINOACID
KR20190026748A (en) 2016-06-07 2019-03-13 아도시아 Compositions in the form of injectable aqueous solutions comprising human glucagon and end-grafted copolyamino acids
GB201611077D0 (en) 2016-06-24 2016-08-10 Arecor Ltd Novel composition
FR3074683B1 (en) * 2017-12-07 2020-01-10 Adocia COMPOSITIONS IN THE FORM OF AN AQUEOUS INJECTION SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINOACID
MA51018A (en) 2017-12-07 2020-10-14 Adocia COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINOACID
CN111670042A (en) 2017-12-07 2020-09-15 阿道恰公司 Compositions in the form of injectable aqueous solutions comprising human glucagon and a polyamino acid copolymer
WO2019110838A1 (en) 2017-12-07 2019-06-13 Adocia Compositions in the form of an injectable aqueous solution comprising human glucagon and a copolyamino acid
FR3083087A1 (en) 2018-06-29 2020-01-03 Adocia COMPOSITIONS IN THE FORM OF AN AQUEOUS INJECTION SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINOACID
WO2019110836A1 (en) 2017-12-07 2019-06-13 Adocia Compositions in the form of an injectable aqueous solution comprising human glucagon and a copolyamino acid
FR3067247A1 (en) 2018-06-07 2018-12-14 Adocia COMPOSITIONS IN THE FORM OF AN INJECTION AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINOACID

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2643967A (en) * 1946-08-31 1953-06-30 Wallerstein Co Inc Concentrate of tyrothricin and its therapeutically active components
NL94376C (en) * 1958-04-28 1960-05-16 Nv Organon PROCESS FOR THE PREPARATION OF INJICIABLE GLACAGON PREPARATIONS WITH EXTENDED ACTION

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2643967A (en) * 1946-08-31 1953-06-30 Wallerstein Co Inc Concentrate of tyrothricin and its therapeutically active components
NL94376C (en) * 1958-04-28 1960-05-16 Nv Organon PROCESS FOR THE PREPARATION OF INJICIABLE GLACAGON PREPARATIONS WITH EXTENDED ACTION

Also Published As

Publication number Publication date
NL6900460A (en) 1969-07-14
IT974528B (en) 1974-07-10
GB1202607A (en) 1970-08-19
DE1900367A1 (en) 1969-09-04
AT283600B (en) 1970-08-10
BE726681A (en) 1969-07-09

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Legal Events

Date Code Title Description
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