FR16C0038I2 - Alkylamines without imidazoles as histamine H-3 receptor ligands and their therapeutic applications - Google Patents
Alkylamines without imidazoles as histamine H-3 receptor ligands and their therapeutic applicationsInfo
- Publication number
- FR16C0038I2 FR16C0038I2 FR16C0038C FR16C0038C FR16C0038I2 FR 16C0038 I2 FR16C0038 I2 FR 16C0038I2 FR 16C0038 C FR16C0038 C FR 16C0038C FR 16C0038 C FR16C0038 C FR 16C0038C FR 16C0038 I2 FR16C0038 I2 FR 16C0038I2
- Authority
- FR
- France
- Prior art keywords
- histamine
- alkylamines
- imidazoles
- therapeutic applications
- receptor ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/16—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring not being further substituted
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- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
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Abstract
The present invention provides new non-imidazole alkylamine derivatives, and their use for preparing medicaments acting as ligands at the H 3 -receptors of histamine.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98401944A EP0978512A1 (en) | 1998-07-29 | 1998-07-29 | Non-imidazole aryloxy (or arylthio) alkylamines as histamine H3-receptor antagonists and their therapeutic applications |
EP98403351A EP0982300A3 (en) | 1998-07-29 | 1998-12-31 | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
EP99941543A EP1100503B1 (en) | 1998-07-29 | 1999-07-29 | Non-imidazole alkylamines as histamine h 3?-receptor ligands and their therapeutic applications |
EP04003944A EP1428820B1 (en) | 1998-07-29 | 1999-07-29 | Non-imidazole alkylamines as histamine H-3-receptor ligands and their therapeutic applications |
Publications (2)
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FR16C0038I1 FR16C0038I1 (en) | 2016-11-11 |
FR16C0038I2 true FR16C0038I2 (en) | 2017-09-22 |
Family
ID=26151677
Family Applications (1)
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FR16C0038C Active FR16C0038I2 (en) | 1998-07-29 | 2016-09-26 | Alkylamines without imidazoles as histamine H-3 receptor ligands and their therapeutic applications |
Country Status (15)
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US (4) | US7138413B1 (en) |
EP (4) | EP0982300A3 (en) |
JP (2) | JP4553487B2 (en) |
AT (2) | ATE326446T1 (en) |
AU (1) | AU5511999A (en) |
BE (1) | BE2016C048I2 (en) |
CA (1) | CA2321881C (en) |
CY (1) | CY2016032I1 (en) |
DE (2) | DE69931409T2 (en) |
DK (2) | DK1100503T3 (en) |
ES (2) | ES2226423T3 (en) |
FR (1) | FR16C0038I2 (en) |
LU (1) | LU93229I2 (en) |
PT (2) | PT1100503E (en) |
WO (1) | WO2000006254A2 (en) |
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- 1999-07-29 AT AT04003944T patent/ATE326446T1/en active
- 1999-07-29 PT PT99941543T patent/PT1100503E/en unknown
- 1999-07-29 PT PT04003944T patent/PT1428820E/en unknown
- 1999-07-29 DK DK99941543T patent/DK1100503T3/en active
- 1999-07-29 ES ES99941543T patent/ES2226423T3/en not_active Expired - Lifetime
- 1999-07-29 AU AU55119/99A patent/AU5511999A/en not_active Abandoned
- 1999-07-29 EP EP99941543A patent/EP1100503B1/en not_active Expired - Lifetime
- 1999-07-29 EP EP04003944A patent/EP1428820B1/en not_active Expired - Lifetime
- 1999-07-29 ES ES04003944T patent/ES2260703T3/en not_active Expired - Lifetime
- 1999-07-29 WO PCT/EP1999/005744 patent/WO2000006254A2/en active IP Right Grant
- 1999-07-29 EP EP06002726A patent/EP2000462A3/en not_active Withdrawn
- 1999-07-29 CA CA2321881A patent/CA2321881C/en not_active Expired - Lifetime
- 1999-07-29 AT AT99941543T patent/ATE276751T1/en active
- 1999-07-29 US US09/622,199 patent/US7138413B1/en not_active Expired - Lifetime
- 1999-07-29 DK DK04003944T patent/DK1428820T3/en active
- 1999-07-29 DE DE69931409T patent/DE69931409T2/en not_active Expired - Lifetime
- 1999-07-29 DE DE69920472T patent/DE69920472T2/en not_active Expired - Lifetime
- 1999-07-29 JP JP2000562103A patent/JP4553487B2/en not_active Expired - Lifetime
-
2004
- 2004-06-01 US US10/856,838 patent/US7169928B2/en not_active Expired - Lifetime
-
2006
- 2006-07-03 US US11/478,682 patent/US7910605B2/en not_active Expired - Fee Related
-
2010
- 2010-06-02 JP JP2010127067A patent/JP5301501B2/en not_active Expired - Lifetime
- 2010-12-15 US US12/968,807 patent/US20110281844A1/en not_active Abandoned
-
2016
- 2016-09-21 LU LU93229C patent/LU93229I2/en unknown
- 2016-09-23 BE BE2016C048C patent/BE2016C048I2/fr unknown
- 2016-09-26 FR FR16C0038C patent/FR16C0038I2/en active Active
- 2016-09-28 CY CY2016032C patent/CY2016032I1/en unknown
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