FR1605453A - Sulphomethyl derivs of polymixins b and e - Google Patents
Sulphomethyl derivs of polymixins b and eInfo
- Publication number
- FR1605453A FR1605453A FR957003A FR957003A FR1605453A FR 1605453 A FR1605453 A FR 1605453A FR 957003 A FR957003 A FR 957003A FR 957003 A FR957003 A FR 957003A FR 1605453 A FR1605453 A FR 1605453A
- Authority
- FR
- France
- Prior art keywords
- ppte
- polymixins
- sulphomethyl
- derivs
- soln
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Sulphomethyl Chemical group 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- 230000000881 depressing effect Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 230000020477 pH reduction Effects 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR966818A FR3405M (fr) | 1962-12-13 | 1964-03-10 | Médicament a base d'une sulfométhyl-polymyxine. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB47190/62A GB1062895A (en) | 1962-12-13 | 1962-12-13 | Sulphomethyl derivatives of polymxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR1605453A true FR1605453A (en) | 1976-02-27 |
Family
ID=10444070
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR957003A Expired FR1605453A (en) | 1962-12-13 | 1963-12-12 | Sulphomethyl derivs of polymixins b and e |
| FR966818A Expired FR3405M (fr) | 1962-12-13 | 1964-03-10 | Médicament a base d'une sulfométhyl-polymyxine. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR966818A Expired FR3405M (fr) | 1962-12-13 | 1964-03-10 | Médicament a base d'une sulfométhyl-polymyxine. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3317506A (enExample) |
| AT (1) | AT249266B (enExample) |
| BE (1) | BE641002A (enExample) |
| BR (1) | BR6355349D0 (enExample) |
| CH (1) | CH438579A (enExample) |
| DE (1) | DE1518440C3 (enExample) |
| DK (1) | DK107559C (enExample) |
| ES (1) | ES294436A1 (enExample) |
| FR (2) | FR1605453A (enExample) |
| GB (1) | GB1062895A (enExample) |
| LU (1) | LU44997A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3476738A (en) * | 1967-12-04 | 1969-11-04 | Upjohn Co | Pentakis(n-(sulfomethyl))circulin and salts thereof |
| US3622665A (en) * | 1969-07-02 | 1971-11-23 | Upjohn Co | Process for treating gram-negative bacterial diseases with pentakis {8 n-sulfomethyl{9 {0 circulin or salt thereof |
| US9724278B2 (en) | 2008-06-13 | 2017-08-08 | Colgate-Palmolive Company | Oral compositions and uses thereof |
| RU2015132569A (ru) | 2013-01-11 | 2017-02-14 | Кселлия Фармасьютикалз Апс | Полимиксины, композиции с ними, способы получения и способы применения |
| EP3166960B1 (en) | 2014-07-09 | 2019-08-07 | Xellia Pharmaceuticals ApS | Low substituted polymyxins and compositions thereof |
| US10532080B2 (en) | 2014-10-03 | 2020-01-14 | Xellia Pharmaceuticals Aps | Sulfomethylated polymixin compositions |
| SG11201702666SA (en) | 2014-10-03 | 2017-04-27 | Xellia Pharmaceuticals Aps | Inhalation device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2599950A (en) * | 1947-04-30 | 1952-06-10 | American Cyanamid Co | Method of preparing polymyxin |
| US3044934A (en) * | 1960-05-19 | 1962-07-17 | Burroughs Wellcome Co | Parenteral administration of methanesulphonate of polymyxin a, b or e |
| US3228836A (en) * | 1962-10-09 | 1966-01-11 | Warner Lambert Pharmaceutical | Aldehyde complexes of colistin and polymyxin antibiotics |
-
1962
- 1962-12-13 GB GB47190/62A patent/GB1062895A/en not_active Expired
-
1963
- 1963-12-04 US US328049A patent/US3317506A/en not_active Expired - Lifetime
- 1963-12-04 CH CH1488163A patent/CH438579A/de unknown
- 1963-12-09 BE BE641002A patent/BE641002A/xx unknown
- 1963-12-10 DE DE1518440A patent/DE1518440C3/de not_active Expired
- 1963-12-11 BR BR155349/63A patent/BR6355349D0/pt unknown
- 1963-12-11 AT AT993063A patent/AT249266B/de active
- 1963-12-11 LU LU44997A patent/LU44997A1/xx unknown
- 1963-12-12 DK DK580063AA patent/DK107559C/da active
- 1963-12-12 ES ES0294436A patent/ES294436A1/es not_active Expired
- 1963-12-12 FR FR957003A patent/FR1605453A/fr not_active Expired
-
1964
- 1964-03-10 FR FR966818A patent/FR3405M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1518440A1 (de) | 1969-06-12 |
| BE641002A (enExample) | 1964-06-09 |
| DE1518440B2 (de) | 1973-03-01 |
| FR3405M (fr) | 1965-07-05 |
| DE1518440C3 (de) | 1973-09-27 |
| DK107559C (da) | 1967-06-12 |
| LU44997A1 (enExample) | 1964-06-11 |
| US3317506A (en) | 1967-05-02 |
| BR6355349D0 (pt) | 1973-07-19 |
| AT249266B (de) | 1966-09-12 |
| CH438579A (de) | 1967-06-30 |
| GB1062895A (en) | 1967-03-22 |
| ES294436A1 (es) | 1964-06-01 |
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