FR1604759A - Isomer of 4-aminomethylcyclohexane carboxylic acid - Google Patents
Isomer of 4-aminomethylcyclohexane carboxylic acidInfo
- Publication number
- FR1604759A FR1604759A FR1604759DA FR1604759A FR 1604759 A FR1604759 A FR 1604759A FR 1604759D A FR1604759D A FR 1604759DA FR 1604759 A FR1604759 A FR 1604759A
- Authority
- FR
- France
- Prior art keywords
- isomer
- active
- antifibrinolytically
- carboxylic acid
- contg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
(A) An antifibrinolytically active isomer of 4-aminomethylcyclohexane carboxylic acid (I). (B) Pharm. prepns. contg. active (I). (C) Process for the prepn. and conversion of the antifibrinolytically inactive isomer of (I) into the active form of at least 90% purity. Treatment of menstrual and surgical bleeding. The unit dosage is from 100-1000 mg. as tablets, capsules, and elixirs for oral use or as a soln. for parenteral use. The isomer of (I) assaying at least 90% antifibrinolytically active material; the isomer moving 135 mm. in 200 min. in a high voltage electrophoresis system on paper at pH 4.5 at 50 V/cm. and 5 mA./cm. as compared with a movement of 25 mm. for alanine. Unit dosage forms contg. 100-1000 mg. active cpd. per unit.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1408563A SE309983B (en) | 1963-12-17 | 1963-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR1604759A true FR1604759A (en) | 1972-01-31 |
Family
ID=20298499
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR998919A Expired FR4270M (en) | 1963-12-17 | 1964-12-16 | |
| FR1604759D Expired FR1604759A (en) | 1963-12-17 | 1965-03-10 | Isomer of 4-aminomethylcyclohexane carboxylic acid |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR998919A Expired FR4270M (en) | 1963-12-17 | 1964-12-16 |
Country Status (14)
| Country | Link |
|---|---|
| AT (3) | AT277205B (en) |
| BE (1) | BE657184A (en) |
| BR (1) | BR6465448D0 (en) |
| CH (1) | CH475192A (en) |
| DE (1) | DE1443422A1 (en) |
| DK (2) | DK125281B (en) |
| ES (1) | ES307169A1 (en) |
| FI (1) | FI42826B (en) |
| FR (2) | FR4270M (en) |
| GB (1) | GB1086952A (en) |
| IL (1) | IL22592A (en) |
| NL (1) | NL6414596A (en) |
| NO (1) | NO121094B (en) |
| SE (1) | SE309983B (en) |
-
1963
- 1963-12-17 SE SE1408563A patent/SE309983B/xx unknown
-
1964
- 1964-12-09 IL IL2259264A patent/IL22592A/en unknown
- 1964-12-15 NO NO15598064A patent/NO121094B/no unknown
- 1964-12-15 NL NL6414596A patent/NL6414596A/xx unknown
- 1964-12-16 FR FR998919A patent/FR4270M/fr not_active Expired
- 1964-12-16 GB GB3597764A patent/GB1086952A/en not_active Expired
- 1964-12-16 ES ES0307169A patent/ES307169A1/en not_active Expired
- 1964-12-16 DK DK617164A patent/DK125281B/en unknown
- 1964-12-16 BE BE657184D patent/BE657184A/xx unknown
- 1964-12-17 BR BR16544864A patent/BR6465448D0/en unknown
- 1964-12-17 AT AT623868A patent/AT277205B/en not_active IP Right Cessation
- 1964-12-17 AT AT624064A patent/AT277207B/en not_active IP Right Cessation
- 1964-12-17 FI FI267364A patent/FI42826B/fi active
- 1964-12-17 CH CH1627764A patent/CH475192A/en not_active IP Right Cessation
- 1964-12-17 AT AT623964A patent/AT277206B/en not_active IP Right Cessation
- 1964-12-17 DE DE19641443422 patent/DE1443422A1/en active Pending
-
1965
- 1965-03-10 FR FR1604759D patent/FR1604759A/en not_active Expired
-
1966
- 1966-06-24 DK DK327066A patent/DK123168B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6414596A (en) | 1965-06-18 |
| AT277205B (en) | 1969-12-10 |
| DK125281B (en) | 1973-01-29 |
| AT277206B (en) | 1969-12-10 |
| DK123168B (en) | 1972-05-23 |
| BE657184A (en) | 1965-04-16 |
| BR6465448D0 (en) | 1973-08-02 |
| SE309983B (en) | 1969-04-14 |
| NO121094B (en) | 1971-01-18 |
| FI42826B (en) | 1970-08-03 |
| AT277207B (en) | 1969-12-10 |
| CH475192A (en) | 1969-07-15 |
| GB1086952A (en) | 1967-10-11 |
| ES307169A1 (en) | 1965-06-01 |
| DE1443422A1 (en) | 1969-01-23 |
| IL22592A (en) | 1968-08-22 |
| FR4270M (en) | 1966-07-11 |
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