FR1604144A - Cerebrospinal meningitis vaccine - Google Patents

Cerebrospinal meningitis vaccine

Info

Publication number
FR1604144A
FR1604144A FR1604144DA FR1604144A FR 1604144 A FR1604144 A FR 1604144A FR 1604144D A FR1604144D A FR 1604144DA FR 1604144 A FR1604144 A FR 1604144A
Authority
FR
France
Prior art keywords
vaccine
organisms
billion
cultures
cerebrospinal meningitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
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French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application granted granted Critical
Publication of FR1604144A publication Critical patent/FR1604144A/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Vaccine against human cerebrospinal meningitis. Microbial strains isolated during an epidemic are separately cultured in vitro by conventional methods, then passaged (48 hrs) several times (pref. 5-6) in the allantoic cavity of the 7-10 day-old chick embryo. Subcultures of the allantoic fluid are used to inoculate industrial cultures. The product is centrifuged, the microbial pellet resuspended, the organisms inactivated (heat, phenol, CH2O, etc.) and then made up into vaccine doses (5-30 strains) contng. 10 billion dead organisms in 0.1 ml., finally lyophilised. Concd. cultures can be obtd., e.g. 500-100 billion organisms per ml., permitting a single intradermal injection of 0.1 ml. of vaccine.
FR1604144D 1968-01-29 1968-01-29 Cerebrospinal meningitis vaccine Expired FR1604144A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR137847 1968-01-29

Publications (1)

Publication Number Publication Date
FR1604144A true FR1604144A (en) 1971-07-12

Family

ID=8645254

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1604144D Expired FR1604144A (en) 1968-01-29 1968-01-29 Cerebrospinal meningitis vaccine

Country Status (3)

Country Link
DE (1) DE1904001A1 (en)
FR (1) FR1604144A (en)
OA (1) OA03309A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0668778A1 (en) * 1992-10-26 1995-08-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES IMMUNIZATION AGAINST $i(NEISSERIA GONORRHOEAE) AND $i(NEISSERIA MENINGITIDIS)

Also Published As

Publication number Publication date
DE1904001A1 (en) 1969-10-02
OA03309A (en) 1970-12-15

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