US6395888B1
(en)
*
|
1996-02-01 |
2002-05-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
WO1996009043A1
(en)
*
|
1994-09-23 |
1996-03-28 |
Alexion Pharmaceuticals, Inc. |
Methods for the treatment of inflammatory joint disease
|
US6956107B2
(en)
|
1998-02-20 |
2005-10-18 |
Tanox, Inc. |
Inhibitors of complement activation
|
AU762050B2
(en)
|
1998-02-20 |
2003-06-19 |
Genentech, Inc. |
Inhibitors of complement activation
|
US7112327B2
(en)
|
1998-02-20 |
2006-09-26 |
Tanox, Inc. |
Inhibition of complement activation
|
DE19913707A1
(en)
*
|
1999-03-26 |
2000-10-05 |
Privates Inst Bioserv Gmbh |
Immunosorbent for sepsis therapy
|
JP2003504019A
(en)
*
|
1999-06-29 |
2003-02-04 |
オートゲン リサーチ プロプライエトリー リミティッド |
Novel genes and their use in regulating obesity, diabetes and energy imbalance
|
EP1287364B1
(en)
|
2000-04-29 |
2008-10-22 |
University Of Iowa Research Foundation |
Diagnostics and therapeutics for macular degeneration-related disorders
|
EP2113516B1
(en)
*
|
2000-10-10 |
2014-05-21 |
Genentech, Inc. |
Antibodies against C5 inhibiting type II endothelial cell activation
|
US20020094332A1
(en)
*
|
2001-01-18 |
2002-07-18 |
Alexion Pharmaceuticals |
Method of prophylaxis against large myocardial infractions
|
WO2002069232A2
(en)
|
2001-02-19 |
2002-09-06 |
Merck Patent Gmbh |
Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
|
US20030109714A1
(en)
*
|
2001-03-22 |
2003-06-12 |
Neil Wishart |
Transition metal mediated process
|
CA2454562A1
(en)
*
|
2001-07-26 |
2003-02-06 |
Alexion Pharmaceuticals, Inc. |
Method of improving cognitive function
|
EP1878441B1
(en)
|
2001-08-17 |
2018-01-24 |
Genentech, Inc. |
Complement pathway inhibitors binding to C5 and C5a without preventing the formation of C5b
|
ES2283594T5
(en)
*
|
2001-08-17 |
2016-03-15 |
Genentech, Inc. |
Inhibitors of the complement pathway that bind to C5 and C5a without preventing the formation of C5b
|
EP1461428B1
(en)
|
2001-12-03 |
2012-03-21 |
Alexion Pharmaceuticals, Inc. |
Method for producing hybrid antibodies
|
US20050221382A1
(en)
*
|
2002-03-18 |
2005-10-06 |
Rother Russell P |
Stratification of patient populations having or suspected of having rheumatoid arthritis
|
ITMI20021527A1
(en)
*
|
2002-07-11 |
2004-01-12 |
Consiglio Nazionale Ricerche |
C5 COMPONENT ANTIBODIES OF COMPLEMENT AND THEIR USE
|
EP1545611B1
(en)
*
|
2002-09-06 |
2016-11-09 |
Alexion Pharmaceuticals, Inc. |
Method of treatment of asthma using antibodies to complement component c5
|
US20050271660A1
(en)
*
|
2002-09-06 |
2005-12-08 |
Alexion Pharmaceuticals, Inc. |
Nebulization of monoclonal antibodies for treating pulmonary diseases
|
US9415102B2
(en)
|
2002-09-06 |
2016-08-16 |
Alexion Pharmaceuticals, Inc. |
High concentration formulations of anti-C5 antibodies
|
US7361339B2
(en)
*
|
2003-01-09 |
2008-04-22 |
Alexion Pharmaceuticals, Inc. |
Methods for reducing morality associated with acute myocardial infarction
|
US20090010937A1
(en)
*
|
2004-01-28 |
2009-01-08 |
Chauhan Anil K |
Membrane Attack Complexes Associated with Circulating Immune Complexes
|
US20070116710A1
(en)
*
|
2004-02-03 |
2007-05-24 |
Leonard Bell |
Methods of treating hemolytic anemia
|
US20050169921A1
(en)
|
2004-02-03 |
2005-08-04 |
Leonard Bell |
Method of treating hemolytic disease
|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
WO2005110481A2
(en)
|
2004-05-14 |
2005-11-24 |
Alexion Pharmaceuticals, Inc. |
Prolongation of survival of an allograft by inhibiting complement activity
|
US7973134B2
(en)
*
|
2004-07-07 |
2011-07-05 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
|
US7935790B2
(en)
*
|
2004-10-04 |
2011-05-03 |
Cell Singaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
|
US7807789B2
(en)
*
|
2004-12-21 |
2010-10-05 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
|
US20090099340A1
(en)
*
|
2007-10-12 |
2009-04-16 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
|
US20070292421A1
(en)
*
|
2005-07-28 |
2007-12-20 |
Feinberg Bruce B |
Method for treating preeclampsia
|
US20100151495A9
(en)
*
|
2005-08-31 |
2010-06-17 |
Cell Signaling Technolgy, Inc. |
Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
|
EP1934867A2
(en)
|
2005-08-31 |
2008-06-25 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in leukemia signaling pathways
|
NZ594285A
(en)
|
2005-11-04 |
2013-02-22 |
Genentech Inc |
USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES
|
WO2009051846A2
(en)
|
2007-10-18 |
2009-04-23 |
Cell Signaling Technology, Inc. |
Translocation and mutant ros kinase in human non-small cell lung carcinoma
|
US20120208824A1
(en)
|
2006-01-20 |
2012-08-16 |
Cell Signaling Technology, Inc. |
ROS Kinase in Lung Cancer
|
US20070196367A1
(en)
*
|
2006-02-22 |
2007-08-23 |
Valentin Dinu |
Methods of preventing and treating Alzheimer's disease, age related macular degeneration and other diseases involving extra-cellular debris through the inhibition of the complement system
|
RU2445975C2
(en)
|
2006-03-02 |
2012-03-27 |
Алексион Фармасьютикалз, Инк. |
Prolongation of allograft survival by complement activity inhibition
|
PT1991275E
(en)
|
2006-03-08 |
2015-02-03 |
Archemix Llc |
Complement binding aptamers and anti-c5 agents useful in the treatment of ocular disorders
|
WO2007106585A1
(en)
*
|
2006-03-15 |
2007-09-20 |
Alexion Pharmaceuticals, Inc. |
Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement
|
EP2006381B1
(en)
|
2006-03-31 |
2016-02-03 |
Chugai Seiyaku Kabushiki Kaisha |
Method for controlling blood pharmacokinetics of antibodies
|
US20090298093A1
(en)
*
|
2006-04-27 |
2009-12-03 |
Roberto Polakiewicz |
Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
|
AU2006343402A1
(en)
*
|
2006-05-01 |
2007-11-15 |
Alexion Pharmaceuticals, Inc. |
Methods for the treatment of muscular dystrophy associated with dysferlin-deficiency
|
EP2826788B1
(en)
|
2006-06-21 |
2017-12-13 |
MUSC Foundation for Research Development |
Targeting complement factor h for treatment of diseases by the use of cr2-fh molecules
|
US7939636B2
(en)
*
|
2006-08-11 |
2011-05-10 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in c-Src signaling pathways
|
US20090258442A1
(en)
*
|
2006-08-31 |
2009-10-15 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
|
NZ575018A
(en)
*
|
2006-09-05 |
2012-04-27 |
Alexion Pharma Inc |
Compositions for the treatment of antibody mediated neuropathies
|
EP3028716B1
(en)
|
2006-10-10 |
2020-09-16 |
Regenesance B.V. |
Complement inhibition for improved nerve regeneration
|
WO2008048689A2
(en)
*
|
2006-10-20 |
2008-04-24 |
Alexion Pharmaceuticals, Inc. |
Methods for the treatment of muscular dystrophy associated with dysferlin-deficiency
|
KR20160092061A
(en)
|
2006-11-02 |
2016-08-03 |
제넨테크, 인크. |
Humanized anti-factor d antibodies
|
EP1972639A3
(en)
|
2007-03-07 |
2008-12-03 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
|
BRPI0809105A2
(en)
*
|
2007-03-22 |
2019-09-10 |
Novartis Ag |
c5 antigens and use of these
|
EP1975184A3
(en)
|
2007-03-26 |
2008-11-26 |
Cell Signaling Technology, Inc. |
Serine or threonine phosphorylation sites
|
US20080238709A1
(en)
*
|
2007-03-28 |
2008-10-02 |
Faramarz Vaziri |
One-way communication apparatus with dynamic key generation
|
US7977462B2
(en)
|
2007-04-19 |
2011-07-12 |
Cell Signaling Technology, Inc. |
Tyrosine phosphorylation sites
|
EP2145902A3
(en)
|
2007-04-19 |
2010-09-29 |
Peter Hornbeck |
Tyrosine phosphorylation sites and antibodies specific for them
|
EP1983003A3
(en)
|
2007-04-19 |
2009-03-11 |
Peter Hornbeck |
Tyrosine phosphorylation sites and antibodies specific for them
|
US20090053831A1
(en)
|
2007-05-01 |
2009-02-26 |
Cell Signaling Technology, Inc. |
Tyrosine phosphorylation sites
|
EP2185594B1
(en)
*
|
2007-08-13 |
2016-04-06 |
VasGene Therapeutics, Inc. |
Cancer treatment using humanized antibodies that bind to ephb4
|
EP4368721A2
(en)
|
2007-09-26 |
2024-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in cdr
|
EP2062920A3
(en)
|
2007-11-21 |
2009-06-17 |
Peter Hornbeck |
Protein phosphorylation by basophilic serine/threonine kinases in insulin signalling pathways
|
US20090220991A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in leukemia signaling pathways
|
EP3023502A1
(en)
|
2008-04-10 |
2016-05-25 |
Cell Signaling Technology, Inc. |
Compositions and methods for detecting egfr mutations in cancer
|
NO2708559T3
(en)
|
2008-04-11 |
2018-08-25 |
|
|
CR20170001A
(en)
|
2008-04-28 |
2017-08-10 |
Genentech Inc |
ANTI FACTOR D HUMANIZED ANTIBODIES
|
EP2280928B1
(en)
*
|
2008-05-01 |
2018-07-25 |
Complexa Inc. |
Vinyl substituted fatty acids
|
US8148088B2
(en)
*
|
2008-07-18 |
2012-04-03 |
Abgent |
Regulation of autophagy pathway phosphorylation and uses thereof
|
WO2010015608A1
(en)
|
2008-08-05 |
2010-02-11 |
Novartis Ag |
Compositions and methods for antibodies targeting complement protein c5
|
AU2014201433B2
(en)
*
|
2008-08-05 |
2016-05-26 |
Novartis Ag |
Compositions and methods for antibodies targeting complement protein C5
|
DK2379066T3
(en)
|
2008-09-16 |
2014-06-30 |
Imunek Farma Ilaç Sanayi Ve Ticaret A S |
APPLICATION OF OPIOID ANTAGONISTS FOR THE PREPARATION OF A MEDICINE FOR THE TREATMENT OF RETAINED DEGENERY DISEASES
|
TWI440469B
(en)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
CN109045296A
(en)
|
2008-11-10 |
2018-12-21 |
阿雷克森制药公司 |
For treating the method and composition of complement associated disorders
|
PL2881402T3
(en)
|
2009-02-12 |
2017-10-31 |
Cell Signaling Technology Inc |
Mutant ROS expression in human liver cancer
|
ES2738700T3
(en)
|
2009-02-13 |
2020-01-24 |
Immunomedics Inc |
Immunoconjugates with an intracellularly cleavable link
|
NZ594638A
(en)
|
2009-02-24 |
2013-03-28 |
Alexion Pharma Inc |
Antibodies containing therapeutic tpo/epo mimetic peptides for treatment of thrombocytopenia type conditions
|
US20100248265A1
(en)
*
|
2009-02-27 |
2010-09-30 |
The Salk Institute For Biological Studies |
Compositions and methods for diagnosis and treatment of cancer
|
JP2012531418A
(en)
*
|
2009-06-23 |
2012-12-10 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
Bispecific antibodies that bind complement proteins
|
US9066925B2
(en)
|
2009-07-02 |
2015-06-30 |
Musc Foundation For Research Development |
Methods of stimulating liver regeneration
|
WO2011034660A1
(en)
|
2009-09-16 |
2011-03-24 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
WO2011040894A1
(en)
*
|
2009-10-01 |
2011-04-07 |
Mustafa Nevzat Ilaç Sanayii A.Ş. |
Topical compositions of opioid antagonists and methods for treating skin conditions therewith
|
KR20120130748A
(en)
|
2009-11-05 |
2012-12-03 |
알렉시온 캠브리지 코포레이션 |
Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis
|
CA2782194C
(en)
|
2009-12-02 |
2018-01-16 |
Immunomedics, Inc. |
Combination of radiolabelled antibodies (rait) and antibody-drug conjugates (adc) for treatment of pancreatic cancer
|
SG183541A1
(en)
*
|
2010-03-01 |
2012-10-30 |
Alexion Pharma Inc |
Methods and compositions for treating degos' disease
|
TWI667346B
(en)
*
|
2010-03-30 |
2019-08-01 |
中外製藥股份有限公司 |
Antibodies with modified affinity to fcrn that promote antigen clearance
|
TR201002473A2
(en)
|
2010-03-31 |
2011-09-21 |
Mustafa Nevzat �La� Sanay�� A.�. |
A method of treating herpes zoster disease using an opiate receptor antagonist.
|
MX2012012689A
(en)
*
|
2010-04-30 |
2013-12-16 |
Alexion Pharma Inc |
Antibodies having reduced immunogenicity in a human.
|
US9011852B2
(en)
|
2010-04-30 |
2015-04-21 |
Alexion Pharmaceuticals, Inc. |
Anti-C5a antibodies
|
EP2569332B1
(en)
|
2010-05-14 |
2019-01-09 |
The Regents of the University of Colorado, A Body Corporate |
Improved complement receptor 2 (cr2) targeting groups
|
KR20130036276A
(en)
|
2010-06-22 |
2013-04-11 |
더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 |
Antibodies to the c3d fragment of complement component 3
|
US20120101108A1
(en)
|
2010-08-06 |
2012-04-26 |
Cell Signaling Technology, Inc. |
Anaplastic Lymphoma Kinase In Kidney Cancer
|
EP2600901B1
(en)
|
2010-08-06 |
2019-03-27 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
DE19177059T1
(en)
|
2010-10-01 |
2021-10-07 |
Modernatx, Inc. |
RIBONUCLEIC ACID CONTAINING N1-METHYL-PSEUDOURACILE AND USES
|
TW201241008A
(en)
*
|
2010-10-01 |
2012-10-16 |
Alexion Pharma Inc |
Polypeptides that bind to human complement component C5
|
AU2011337704B2
(en)
|
2010-11-30 |
2017-06-15 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
EP2468295A1
(en)
|
2010-12-21 |
2012-06-27 |
Affiris AG |
Vaccines based on peptides of the complement protein C5a
|
KR20200103845A
(en)
|
2011-02-25 |
2020-09-02 |
추가이 세이야쿠 가부시키가이샤 |
FcγRIIb-specific Fc antibody
|
WO2012135805A2
(en)
|
2011-03-31 |
2012-10-04 |
modeRNA Therapeutics |
Delivery and formulation of engineered nucleic acids
|
JP5838486B2
(en)
|
2011-04-15 |
2016-01-06 |
ソウル大学校産学協力団Snu R&Db Foundation |
Complex comprising anti-cotinine antibody bound to conjugate of conjugate substance and cotinine and use thereof
|
WO2012151199A1
(en)
|
2011-05-02 |
2012-11-08 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
EP2723361B1
(en)
|
2011-06-22 |
2019-10-30 |
Apellis Pharmaceuticals, Inc. |
Methods of treating chronic disorders with complement inhibitors
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
TW201817744A
(en)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
Therapeutic antigen-binding molecule with a FcRn-binding domain that promotes antigen clearance
|
EP3939996A1
(en)
|
2011-09-30 |
2022-01-19 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
|
LT3682905T
(en)
|
2011-10-03 |
2022-02-25 |
Modernatx, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
CN104080909A
(en)
|
2011-11-30 |
2014-10-01 |
中外制药株式会社 |
Drug containing carrier into cell for forming immune complex
|
PL2791160T3
(en)
|
2011-12-16 |
2022-06-20 |
Modernatx, Inc. |
Modified mrna compositions
|
CN106831985A
(en)
|
2011-12-21 |
2017-06-13 |
诺华股份有限公司 |
The composition and method of the P factors are targeted for antibody
|
LT2817329T
(en)
|
2012-02-20 |
2019-04-10 |
Swedish Orphan Biovitrum Ab (Publ) |
Polypeptides binding to human complement c5
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
DE18200782T1
(en)
|
2012-04-02 |
2021-10-21 |
Modernatx, Inc. |
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH DISEASES IN HUMANS
|
IN2014KN02324A
(en)
|
2012-04-06 |
2015-05-01 |
Omeros Corp |
|
ES2655842T3
(en)
|
2012-04-18 |
2018-02-21 |
Cell Signaling Technology, Inc. |
EGFR and ROS1 in cancer
|
CN104717975A
(en)
|
2012-06-18 |
2015-06-17 |
奥默罗斯公司 |
Compositions and methods of inhibiting MASP-1 and/or MASP-2 and/or MASP-3 for the treatment of various diseases and disorders
|
WO2014028560A2
(en)
|
2012-08-14 |
2014-02-20 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
JP2015535212A
(en)
|
2012-08-17 |
2015-12-10 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト |
Compositions and methods for detecting complement activation
|
US10413620B2
(en)
|
2012-08-17 |
2019-09-17 |
The Regents Of The University Of Colorado, A Body Corporate |
Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging
|
KR102273985B1
(en)
|
2012-08-24 |
2021-07-06 |
추가이 세이야쿠 가부시키가이샤 |
FcγRIIb-specific Fc region variant
|
TW201418707A
(en)
*
|
2012-09-21 |
2014-05-16 |
Alexion Pharma Inc |
Screening assays for complement component C5 antagonists
|
RS63237B1
(en)
|
2012-11-26 |
2022-06-30 |
Modernatx Inc |
Terminally modified rna
|
HRP20220399T1
(en)
|
2012-12-13 |
2022-05-13 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
|
KR101638931B1
(en)
*
|
2013-01-31 |
2016-07-12 |
서울대학교산학협력단 |
C5 antibodies and methods for the prevention and treatment of complement-associated disease
|
LT2970974T
(en)
|
2013-03-14 |
2017-12-11 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions and methods of use thereof
|
PE20151893A1
(en)
|
2013-03-14 |
2015-12-30 |
Parkash Gill |
TREATMENT OF CANCER USING ANTIBODIES THAT BIND GRP78 ON THE CELLULAR SURFACE
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
EP2978451B1
(en)
|
2013-03-29 |
2019-11-27 |
Alexion Pharmaceuticals, Inc. |
Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5
|
KR102318483B1
(en)
|
2013-04-02 |
2021-10-27 |
추가이 세이야쿠 가부시키가이샤 |
Fc region variant
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
EP3290922A1
(en)
|
2013-08-07 |
2018-03-07 |
Alexion Pharmaceuticals, Inc. |
Atypical hemolytic uremic syndrome (ahus) biomarker proteins
|
CR20160132A
(en)
|
2013-08-12 |
2016-08-25 |
Genentech Inc |
COMPOSITIONS AND METHOD TO TREAT CONDITIONS ASSOCIATED WITH THE COMPLEMENT
|
EP3033093A1
(en)
*
|
2013-08-16 |
2016-06-22 |
Alexion Pharmaceuticals, Inc. |
Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant
|
NZ718153A
(en)
|
2013-08-28 |
2022-05-27 |
Ipc Res Llc |
Stable polypeptides binding to human complement c5
|
LT3039033T
(en)
|
2013-08-28 |
2019-10-25 |
Affibody Ab |
Binding polypeptides having a mutated scaffold
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
EA201690675A1
(en)
|
2013-10-03 |
2016-08-31 |
Модерна Терапьютикс, Инк. |
POLYNUCLEOTES ENCODING THE RECEPTOR OF LOW DENSITY LIPOPROTEINS
|
US20150104445A1
(en)
|
2013-10-10 |
2015-04-16 |
Viropharma Holdings Limited |
Methods of inhibiting the alternative pathway of complement immune system activation and compositions used therein
|
IL294470B1
(en)
|
2013-12-12 |
2024-08-01 |
Alnylam Pharmaceuticals Inc |
Complement component irna compositions and methods of use thereof
|
WO2015103438A2
(en)
|
2014-01-02 |
2015-07-09 |
Genelux Corporation |
Oncolytic virus adjunct therapy with agents that increase virus infectivity
|
EP3102701A1
(en)
|
2014-02-07 |
2016-12-14 |
Novartis AG |
Impact of genetic factors on disease progression and response to anti-c5 antibody in geographic atrophy
|
CA2939626C
(en)
*
|
2014-02-20 |
2023-01-17 |
Allergan, Inc. |
Complement component c5 antibodies
|
WO2015126548A1
(en)
|
2014-02-21 |
2015-08-27 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to trop-2 expressing cells
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
EP3110423A4
(en)
|
2014-02-25 |
2017-09-20 |
Achillion Pharmaceuticals, Inc. |
Ether compounds for treatment of complement mediated disorders
|
BR112016019286B1
(en)
*
|
2014-02-26 |
2024-02-20 |
Allergan, Inc. |
ANTI-C5 ANTIBODY
|
NZ631007A
(en)
|
2014-03-07 |
2015-10-30 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
MX2016014160A
(en)
|
2014-05-01 |
2017-02-16 |
Genentech Inc |
Anti-factor d antibody variants and uses thereof.
|
BR112016025751A2
(en)
|
2014-05-05 |
2018-01-16 |
Regeneron Pharma |
rodent, and methods for making a humanized rodent and mouse and for identifying a compound capable of modulating complement activation
|
PT3628680T
(en)
|
2014-06-12 |
2021-10-07 |
Ra Pharmaceuticals Inc |
Modulation of complement activity
|
WO2015200260A1
(en)
|
2014-06-24 |
2015-12-30 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
WO2016033382A1
(en)
*
|
2014-08-27 |
2016-03-03 |
Capnia, Inc. |
Methods for immune globulin administration
|
EP3191591A1
(en)
|
2014-09-12 |
2017-07-19 |
Alnylam Pharmaceuticals, Inc. |
Polynucleotide agents targeting complement component c5 and methods of use thereof
|
CA2961774C
(en)
|
2014-10-07 |
2023-05-23 |
Immunomedics, Inc. |
Neoadjuvant use of antibody-drug conjugates
|
EP3207132B1
(en)
*
|
2014-10-15 |
2019-07-31 |
Alexion Pharmaceuticals, Inc. |
Methods of shifting an isoelectric profile of a protein product and uses thereof
|
TR201903267T4
(en)
|
2014-10-15 |
2019-03-21 |
Alexion Pharma Inc |
Replication methods of large-scale eculizumab production cell culture.
|
WO2016061165A1
(en)
|
2014-10-15 |
2016-04-21 |
Alexion Pharmaceuticals, Inc. |
Methods of culturing a cell
|
WO2016094834A2
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
A method for treating a complement mediated disorder caused by an infectious agent in a patient
|
SI3233921T1
(en)
|
2014-12-19 |
2022-01-31 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c5 antibodies and methods of use
|
JP2018511557A
(en)
|
2015-01-22 |
2018-04-26 |
中外製薬株式会社 |
Combination and use of two or more anti-C5 antibodies
|
RS62630B9
(en)
|
2015-01-28 |
2022-04-29 |
Ra Pharmaceuticals Inc |
Modulators of complement activity
|
TR201904903T4
(en)
|
2015-03-25 |
2019-05-21 |
Alexion Pharma Inc |
A method for measuring the protease activity of C3 and C5 convertase of the alternative complement pathway.
|
WO2016151558A1
(en)
|
2015-03-25 |
2016-09-29 |
Alexion Pharmaceuticals, Inc. |
A method for measuring the protease activity of factor d of the alternative complement pathway
|
CA2981543A1
(en)
|
2015-04-22 |
2016-10-27 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
EP3288586A1
(en)
|
2015-05-01 |
2018-03-07 |
Alexion Pharmaceuticals, Inc. |
Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of kindney thansplant
|
WO2016196070A1
(en)
|
2015-06-03 |
2016-12-08 |
Children's Hospital Medical Center |
Compositions and methods for treating neonatal biliary atresia
|
US11840564B2
(en)
|
2015-06-09 |
2023-12-12 |
Children's Hospital Medical Center |
Dosing algorithm for complement inhibitor
|
EP4365291A3
(en)
|
2015-06-12 |
2024-08-14 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions and methods of use thereof
|
CN114796501A
(en)
|
2015-06-25 |
2022-07-29 |
免疫医疗公司 |
Methods of treating cancer with combinations of antibodies and therapeutic agents
|
EP3313437A1
(en)
*
|
2015-06-26 |
2018-05-02 |
Alexion Pharmaceuticals, Inc. |
A method for treating a patient in compliance with vaccination with eculizumab or an eculizumab variant
|
EP3316885B1
(en)
|
2015-07-01 |
2021-06-23 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
WO2017035351A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of medical disorders
|
AR105808A1
(en)
|
2015-08-26 |
2017-11-08 |
Achillion Pharmaceuticals Inc |
AMIDA COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
|
WO2017035405A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of immune and inflammatory disorders
|
AR105809A1
(en)
|
2015-08-26 |
2017-11-08 |
Achillion Pharmaceuticals Inc |
COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
|
WO2017035357A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Phosphonate compounds for treatment of medical disorders
|
WO2017035401A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amide compounds for treatment of immune and inflammatory disorders
|
WO2017035361A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Disubstituted compounds for the treatment of medical disorders
|
WO2017035408A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Compounds for treatment of immune and inflammatory disorders
|
US10385097B2
(en)
|
2015-08-26 |
2019-08-20 |
Achillion Pharmaceuticals, Inc. |
Ether compounds for treatment of medical disorders
|
AR106018A1
(en)
|
2015-08-26 |
2017-12-06 |
Achillion Pharmaceuticals Inc |
ARYL, HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS
|
EP3340983B1
(en)
|
2015-08-26 |
2023-10-04 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
|
EP3328885A1
(en)
|
2015-09-11 |
2018-06-06 |
Bruce Andrien |
Recombinant glycosylated eculizumab and eculizumab variants
|
WO2017048495A1
(en)
|
2015-09-14 |
2017-03-23 |
Children's Hospital Medical Center |
Methods and compositions for treatment of gaucher disease via modulation of c5a receptor
|
WO2017062649A1
(en)
|
2015-10-07 |
2017-04-13 |
Alexion Pharmaceuticals, Inc. |
A method for treating age-related macular degeneration in a patient
|
TW201718014A
(en)
|
2015-10-12 |
2017-06-01 |
諾華公司 |
Use of C5 inhibitors in Transplant Associated Microangiopathy
|
JP2018534930A
(en)
|
2015-10-30 |
2018-11-29 |
ジェネンテック, インコーポレイテッド |
Anti-factor D antibodies and conjugates
|
EP3368073B1
(en)
|
2015-10-30 |
2024-05-15 |
Alexion Pharmaceuticals, Inc. |
A method of inhibiting exacerbations of t cell-mediated allograft vasculopathy
|
WO2017075252A1
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-factor d antibody variant conjugates and uses thereof
|
CN108697759B
(en)
|
2015-12-16 |
2022-08-02 |
Ra制药公司 |
Modulators of complement activity
|
WO2017104779A1
(en)
|
2015-12-18 |
2017-06-22 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c5 antibodies and methods of use
|
AU2017269839A1
(en)
|
2016-05-27 |
2018-11-22 |
Alexion Pharmaceuticals, Inc. |
Methods for treatment of refractory generalized myasthenia gravis
|
CN109310760A
(en)
|
2016-06-07 |
2019-02-05 |
诺华股份有限公司 |
Anti- C5 antibody administration scheme
|
EP3469083A1
(en)
|
2016-06-10 |
2019-04-17 |
Alnylam Pharmaceuticals, Inc. |
COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
|
CA3027487A1
(en)
|
2016-06-14 |
2017-12-21 |
Regeneron Pharmaceuticals, Inc. |
Anti-c5 antibodies and uses thereof
|
MY187848A
(en)
*
|
2016-06-17 |
2021-10-26 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
ES2902006T3
(en)
|
2016-06-27 |
2022-03-24 |
Achillion Pharmaceuticals Inc |
Quinazoline and indole compounds to treat medical disorders
|
JOP20170154B1
(en)
|
2016-08-01 |
2023-03-28 |
Omeros Corp |
Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders
|
CA3026050A1
(en)
|
2016-08-05 |
2018-02-08 |
Chugai Seiyaku Kabushiki Kaisha |
Composition for prophylaxis or treatment of il-8 related diseases
|
US20190276524A1
(en)
|
2016-10-12 |
2019-09-12 |
Alexion Pharmaceuticals, Inc. |
Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant
|
EP3526248A4
(en)
|
2016-10-17 |
2020-07-08 |
Musc Foundation for Research Development |
Compositions and methods for treating central nervous system injury
|
JP7096240B2
(en)
|
2016-10-19 |
2022-07-05 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
Method for Quantifying Unbound C5 in Sample
|
ES2888904T3
(en)
|
2016-10-19 |
2022-01-10 |
Alexion Pharma Inc |
A method of quantifying unbound C5a in a sample
|
EP3532845A1
(en)
|
2016-10-27 |
2019-09-04 |
Alexion Pharmaceuticals, Inc. |
Assay for c5b-9 deposition in complement-associated disorders
|
BR112019011053A2
(en)
|
2016-12-07 |
2019-10-15 |
Ra Pharmaceuticals Inc |
complement activity modulators
|
TW202412841A
(en)
|
2017-01-31 |
2024-04-01 |
日商中外製藥股份有限公司 |
Use of anti-c5 antibody in manufacture of a pharmaceutical composition for treatment or prevention of a c5-related disease
|
CN110603252A
(en)
|
2017-03-01 |
2019-12-20 |
艾其林医药公司 |
Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders
|
WO2018160891A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceutical, Inc. |
Pharmaceutical compounds for treatment of medical disorders
|
EP3589287B1
(en)
|
2017-03-01 |
2022-09-14 |
Achillion Pharmaceuticals, Inc. |
Macrocyclic compounds for treatment of medical disorders
|
JP7251792B2
(en)
|
2017-03-23 |
2023-04-04 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
Anti-C5a Antibodies and Their Uses
|
US11112411B2
(en)
|
2017-03-31 |
2021-09-07 |
Alexion Pharmaceuticals, Inc. |
Method for simultaneous quantification of ALXN1210 and eculizumab in human serum or urine
|
US10376595B2
(en)
|
2017-04-03 |
2019-08-13 |
Inflarx Gmbh |
Treatment of inflammatory diseases with inhibitors of C5a activity
|
JP7486415B2
(en)
|
2017-04-03 |
2024-05-17 |
インフラルクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
Treatment of inflammatory diseases with inhibitors of C5a activity
|
EP3612561A1
(en)
|
2017-04-19 |
2020-02-26 |
Alexion Pharmaceuticals, Inc. |
Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant
|
KR102656199B1
(en)
*
|
2017-04-21 |
2024-04-09 |
볼루션 이뮤노 파마슈티컬스 에스에이 |
Coversin for the treatment of autoimmune blistering disease
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
ES2967965T3
(en)
|
2017-05-22 |
2024-05-06 |
Alexion Pharma Inc |
Dosage and administration of anti-C5 antibodies for the treatment of protein-losing enteropathy in patients
|
KR102576012B1
(en)
|
2017-07-27 |
2023-09-07 |
알렉시온 파마슈티칼스, 인코포레이티드 |
High Concentration Anti-C5 Antibody Formulation
|
US20190038623A1
(en)
|
2017-08-02 |
2019-02-07 |
Achillion Pharmaceuticals, Inc. |
Therapeutic regimens for treatment of paroxysmal nocturnal hemoglobinuria
|
AU2018345625A1
(en)
|
2017-10-04 |
2020-04-16 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-C5 antibodies for treatment of patients with Membranoproliferative glomerulonephritis
|
AU2018354404A1
(en)
|
2017-10-26 |
2020-04-16 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-C5 antibodies for treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) and Atypical Hemolytic Uremic Syndrome (aHUS)
|
US11866701B2
(en)
|
2017-11-01 |
2024-01-09 |
Alnylam Pharmaceuticals, Inc. |
Complement component C3 iRNA compositions and methods of use thereof
|
WO2019105916A1
(en)
|
2017-11-29 |
2019-06-06 |
F. Hoffmann-La Roche Ag |
Target interference suppressed anti-drug antibody assay
|
EP3717004A4
(en)
|
2017-12-01 |
2021-12-01 |
Children's Hospital Medical Center |
Compositions for interferon blockade and methods of using same
|
WO2019118556A1
(en)
|
2017-12-13 |
2019-06-20 |
Regeneron Pharmaceuticals, Inc. |
Anti-c5 antibody combinations and uses thereof
|
SG11202012712YA
(en)
*
|
2018-06-19 |
2021-01-28 |
Atarga Llc |
Antibody molecules to complement component 5 and uses thereof
|
CR20210103A
(en)
|
2018-08-01 |
2021-03-22 |
Chugai Pharmaceutical Co Ltd |
A pharmaceutical composition for use in the treatment or prevention of a c5-related disease and a method for treating or preventing a c5-related disease
|
WO2020041301A1
(en)
|
2018-08-20 |
2020-02-27 |
Achillion Pharmaceuticals, Inc. |
Pharmaceutical compounds for the treatment of complement factor d medical disorders
|
JP7443375B2
(en)
|
2018-09-06 |
2024-03-05 |
アキリオン ファーマシューティカルズ, インコーポレーテッド |
Macrocyclic compounds for the treatment of medical disorders
|
MX2021002640A
(en)
|
2018-09-06 |
2021-07-16 |
Achillion Pharmaceuticals Inc |
Morphic forms of complement factor d inhibitors.
|
JP2022500427A
(en)
|
2018-09-17 |
2022-01-04 |
国立大学法人京都大学 |
Administration of anti-C5 agents for the treatment of liver injury or liver failure
|
JP2022501378A
(en)
|
2018-09-21 |
2022-01-06 |
アレクシオン ファーマシューティカルズ インコーポレイテッドAlexion Pharmaceuticals, Inc. |
Eculizumab for the treatment of neuromyelitis optica
|
CN112996497A
(en)
|
2018-09-25 |
2021-06-18 |
艾其林医药公司 |
Morphic forms of complement factor D inhibitors
|
US20210388070A1
(en)
|
2018-10-30 |
2021-12-16 |
Alexion Pharmaceuticals, Inc. |
Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions
|
EP3873602B1
(en)
|
2018-10-30 |
2023-12-06 |
Alexion Pharmaceuticals, Inc. |
Subcutaneous dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh)
|
WO2020106724A1
(en)
|
2018-11-20 |
2020-05-28 |
Alexion Pharmaceuticals, Inc. |
Methods for treatment of refractory generalized myasthenia gravis in pediatric patients
|
EP3884052A1
(en)
|
2018-11-23 |
2021-09-29 |
Silence Therapeutics GmbH |
Nucleic acids for inhibiting expression of c3 in a cell
|
EP3730617A1
(en)
|
2019-04-26 |
2020-10-28 |
Silence Therapeutics GmbH |
Nucleic acids for inhibiting expression of c3 in a cell
|
GB2583560A
(en)
|
2018-12-11 |
2020-11-04 |
Admirx Inc |
Fusion protein constructs for complement associated disease
|
DK3914617T3
(en)
|
2019-01-25 |
2024-05-27 |
Alexion Pharma Inc |
DOSAGE AND ADMINISTRATION OF ANTI-C5 ANTIBODIES FOR THE TREATMENT OF ATYPICAL HEMOLYTIC UREMIC SYNDROME (AHUS)
|
US20220227851A1
(en)
|
2019-05-24 |
2022-07-21 |
Alexion Pharmaceuticals, Inc. |
Methods of treating vitiligo using an anti-c5 antibody
|
US20220275070A1
(en)
|
2019-07-31 |
2022-09-01 |
Hoffmann-La Roche Inc. |
Dosage and administration regimen for the treatment or prevention of c5-related diseases by the use of the anti-c5 antibody crovalimab
|
CN115137815A
(en)
|
2019-07-31 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
Dosage and administration regimen for treating or preventing C5-related diseases by using anti-C5 antibody covalenzumab
|
WO2021026160A1
(en)
|
2019-08-05 |
2021-02-11 |
Alexion Pharmaceuticals, Inc. |
Methods for treatment of refractory generalized myasthenia gravis with eculizumab
|
CN114981430A
(en)
|
2019-08-27 |
2022-08-30 |
赛伦斯治疗有限责任公司 |
Nucleic acid for inhibiting C3 expression in cells
|
MX2022004726A
(en)
|
2019-10-22 |
2022-05-13 |
Alnylam Pharmaceuticals Inc |
Complement component c3 irna compositions and methods of use thereof.
|
JP2023507852A
(en)
|
2019-12-23 |
2023-02-27 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
Methods of treating pregnancy-associated atypical hemolytic uremic syndrome using anti-C5 antibodies
|
WO2021154941A1
(en)
|
2020-01-31 |
2021-08-05 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
|
WO2021178607A1
(en)
|
2020-03-05 |
2021-09-10 |
Alnylam Pharmaceuticals, Inc. |
Complement component c3 irna compositions and methods of use thereof for treating or preventing complement component c3-associated diseases
|
CA3172421A1
(en)
|
2020-03-27 |
2021-09-30 |
Niels C. Riedemann |
Inhibitors of c5a for the treatment of corona virus infection
|
JP2023522208A
(en)
|
2020-04-16 |
2023-05-29 |
アシスタンス ピュブリック-オピト ド パリ |
Methods of treating complement-mediated disorders caused by viruses
|
AU2021265813A1
(en)
|
2020-04-30 |
2022-11-10 |
Alnylam Pharmaceuticals, Inc. |
Complement factor B (CFB) iRNA compositions and methods of use thereof
|
JP2023526051A
(en)
|
2020-05-12 |
2023-06-20 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
Use of complement factor D inhibitors alone or in combination with anti-C5 antibodies for the treatment of paroxysmal nocturnal hemoglobinuria
|
US20230235080A1
(en)
|
2020-06-03 |
2023-07-27 |
Bionecure Therapeutics, Inc. |
Trophoblast cell-surface antigen-2 (trop-2) antibodies
|
JP2023530977A
(en)
|
2020-06-16 |
2023-07-20 |
エフ. ホフマン-ラ ロシュ アーゲー |
Method for Determining Antibody Free Antigen in a Sample
|
WO2021262329A1
(en)
|
2020-06-24 |
2021-12-30 |
Alexion Pharmaceuticals, Inc. |
Subcutaneous (sc) administration of anti-c5 antibodies for treatment of complement-associated conditions
|
US20230256114A1
(en)
|
2020-07-07 |
2023-08-17 |
Bionecure Therapeutics, Inc. |
Novel maytansinoids as adc payloads and their use for the treatment of cancer
|
WO2022012606A1
(en)
*
|
2020-07-15 |
2022-01-20 |
Biosion Inc. |
Antibodies binding c5 and uses thereof
|
WO2022150260A1
(en)
|
2021-01-05 |
2022-07-14 |
Alnylam Pharmaceuticals, Inc. |
COMPLEMENT COMPONENT 9 (C9) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
EP4281472A1
(en)
|
2021-01-22 |
2023-11-29 |
Alexion Pharmaceuticals, Inc. |
Methods of treating complement mediated thrombotic microangiopathy using an anti-c5 antibody
|
WO2022159984A1
(en)
|
2021-01-22 |
2022-07-28 |
Bionecure Therapeutics, Inc. |
Anti-her-2/trop-2 constructs and uses thereof
|
EP4342497A1
(en)
|
2021-05-10 |
2024-03-27 |
Kawasaki Institute of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|
CA3220629A1
(en)
|
2021-05-28 |
2022-12-01 |
Tobin J. CAMMETT |
Methods for detecting cm-tma biomarkers
|
WO2023023220A1
(en)
|
2021-08-20 |
2023-02-23 |
Alexion Pharmaceuticals, Inc. |
Methods for treating sickle cell disease or beta thalassemia using a complement alternative pathway inhibitor
|
CA3230589A1
(en)
|
2021-09-02 |
2023-03-09 |
Sibylle DAMES |
Nucleic acids for inhibiting expression of complement factor b (cfb) in a cell
|
WO2023044370A2
(en)
|
2021-09-17 |
2023-03-23 |
Alnylam Pharmaceuticals, Inc. |
Irna compositions and methods for silencing complement component 3 (c3)
|
EP4402174A1
(en)
|
2021-09-17 |
2024-07-24 |
Novartis AG |
Methods for prevention of graft rejection in xenotransplantation
|
AU2022378567A1
(en)
|
2021-10-29 |
2024-04-11 |
Alnylam Pharmaceuticals, Inc. |
Complement factor b (cfb) irna compositions and methods of use thereof
|
KR20230105972A
(en)
|
2022-01-05 |
2023-07-12 |
주식회사 카나프테라퓨틱스 |
ANTI-C3b ANTIBODY OR ANTI-C5 ANTIBODY CONJUGATED WITH ANGIOGENESIS INHIBITOR AND USE THEREOF
|
CN116712390B
(en)
*
|
2023-08-04 |
2023-11-14 |
上海览屹医药科技有限公司 |
High-concentration high-stability antibody preparation and preparation method thereof
|