FR07C0073I2 - PAPILLOMAVIRUS VACCINE - Google Patents

PAPILLOMAVIRUS VACCINE

Info

Publication number
FR07C0073I2
FR07C0073I2 FR07C0073C FR07C0073C FR07C0073I2 FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2 FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 C FR07C0073 C FR 07C0073C FR 07C0073 I2 FR07C0073 I2 FR 07C0073I2
Authority
FR
France
Prior art keywords
antibodies
useful
papillomavirus vaccine
mimics
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR07C0073C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25416951&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR07C0073(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Georgetown University filed Critical Georgetown University
Publication of FR07C0073I1 publication Critical patent/FR07C0073I1/fr
Application granted granted Critical
Publication of FR07C0073I2 publication Critical patent/FR07C0073I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

A recombinantly produced L1 major capsid protein which mimics conformational neutralizing epitopes on human and animal papilloma virions is provided. The recombinant proteins are useful as vaccines protective against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.
FR07C0073C 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE Active FR07C0073I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90310992A 1992-06-25 1992-06-25
PCT/US1993/006109 WO1994000152A1 (en) 1992-06-25 1993-06-24 Papillomavirus vaccines

Publications (2)

Publication Number Publication Date
FR07C0073I1 FR07C0073I1 (en) 2008-01-02
FR07C0073I2 true FR07C0073I2 (en) 2012-08-03

Family

ID=25416951

Family Applications (1)

Application Number Title Priority Date Filing Date
FR07C0073C Active FR07C0073I2 (en) 1992-06-25 2007-12-21 PAPILLOMAVIRUS VACCINE

Country Status (12)

Country Link
US (2) US20020068326A1 (en)
EP (2) EP0647140B1 (en)
AT (1) ATE380871T1 (en)
AU (1) AU697743C (en)
DE (9) DE122007000099I1 (en)
DK (1) DK0647140T3 (en)
ES (1) ES2294778T3 (en)
FR (1) FR07C0073I2 (en)
LU (8) LU91395I2 (en)
NL (8) NL300315I2 (en)
PT (1) PT647140E (en)
WO (1) WO1994000152A1 (en)

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US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
US8062642B1 (en) 1993-03-09 2011-11-22 University Of Rochester Production of papillomavirus capsid protein and virus-like particles
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US5888516A (en) * 1994-05-16 1999-03-30 Merck & Co. Inc. Recombinant papillomavirus vaccines
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AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
AU683564B2 (en) * 1994-05-17 1997-11-13 University Of Queensland, The Recombinant papilloma virus L1
HUT77337A (en) * 1994-09-22 1998-03-30 Merck & Co. Inc. Dna encoding human papilloma virus type 6a
WO1996011272A2 (en) 1994-10-07 1996-04-18 Medigene Gesellschaft Für Molekularbiologische Diagnostik, Theraphie Und Technologie Mbh Papilloma virus-like particles, fusion proteins and process for producing the same
US5820870A (en) * 1995-03-22 1998-10-13 Merck & Co., Inc. Recombinant human papillomavirus type 18 vaccine
US5840306A (en) * 1995-03-22 1998-11-24 Merck & Co., Inc. DNA encoding human papillomavirus type 18
IL117459A (en) * 1995-03-22 2005-11-20 Merck & Co Inc Dna encoding human papillomavirus type 18
US6908615B1 (en) 1996-03-18 2005-06-21 Merck & Co., Inc. DNA encoding human papilloma virus type 18
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EP1000157A1 (en) * 1997-07-03 2000-05-17 University Technology Corporation Homogeneous human papilloma virus capsomere containing compositions, methods for manufacture, and the use thereof as diagnostic, prophylactic or therapy
US6228368B1 (en) 1997-10-06 2001-05-08 Loyola University Of Chicago Papilloma virus capsomere formulations and method of use
US7494658B2 (en) 1998-02-20 2009-02-24 Medigene Ag Papilloma virus truncated L1 protein and fusion protein constructs
US7182947B2 (en) 1998-02-20 2007-02-27 Medigene Ag Papillomavirus truncated L1 protein and fusion protein constructs
US20020039584A1 (en) 1998-02-20 2002-04-04 Medigene Ag Papilloma virus capsomere vaccine formulations and methods of use
CA2229955C (en) 1998-02-20 2003-12-09 Medigene Gmbh Papilloma virus capsomere vaccine formulations and methods of use
US6926897B1 (en) 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
CA2337101A1 (en) * 1998-07-13 2000-01-20 Loyola University Of Chicago Papillomavirus cellular receptor
US6692752B1 (en) 1999-09-08 2004-02-17 Smithkline Beecham Biologicals S.A. Methods of treating human females susceptible to HSV infection
CN100558401C (en) * 1998-10-16 2009-11-11 史密丝克莱恩比彻姆生物有限公司 Adjuvant system and vaccine
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
US7247433B2 (en) 2001-08-13 2007-07-24 University Of Rochester Transcutaneous immunization against papillomavirus with papillomavirus virus-like particles
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
DK1944318T3 (en) 2003-07-21 2011-06-14 Transgene Sa Multifunctional cytokines
TWI457133B (en) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa Novel composition
LT2484375T (en) 2006-09-26 2018-07-10 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
KR101532062B1 (en) 2007-03-02 2015-06-26 글락소스미스클라인 바이오로지칼즈 에스.에이. Novel method and compositions
AR071910A1 (en) 2008-05-26 2010-07-21 Cadila Healthcare Ltd COMBINED VACCINE FOR THE HUMAN PAPILOMA AND THE SARAMPION. VECTOR. GUEST.
GB0815872D0 (en) 2008-09-01 2008-10-08 Pasteur Institut Novel method and compositions
GB0820822D0 (en) 2008-11-13 2008-12-24 Inst Catala D Oncologia Novel product and processes
EP2414512A1 (en) * 2009-04-03 2012-02-08 Deutsches Krebsforschungszentrum Enhanced production of papillomavirus-like particles with a modified baculovirus expression system
AU2010256461B2 (en) 2009-06-05 2016-03-17 Access To Advanced Health Institute Synthetic glucopyranosyl lipid adjuvants
WO2011026111A1 (en) 2009-08-31 2011-03-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Oral delivery of a vaccine to the large intestine to induce mucosal immunity
WO2011127360A1 (en) 2010-04-08 2011-10-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education B-cell antigen presenting cell assay
EP3632463A1 (en) 2011-04-08 2020-04-08 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
PL2811981T3 (en) 2012-02-07 2019-09-30 Infectious Disease Research Institute Improved adjuvant formulations comprising tlr4 agonists and methods of using the same
PT2850431T (en) 2012-05-16 2018-07-23 Immune Design Corp Vaccines for hsv-2
EP3587455A1 (en) 2012-10-23 2020-01-01 Emory University Gm-csf and il-4 conjugates, compositions, and methods related thereto
KR102039520B1 (en) 2013-04-18 2019-11-01 이뮨 디자인 코포레이션 GLA monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
US11801223B2 (en) 2013-12-31 2023-10-31 Access To Advanced Health Institute Single vial vaccine formulations
US10962534B2 (en) 2016-02-22 2021-03-30 Boehringer Ingelheim Vetmedica Gmbh Method for the immobilization of biomolecules
JP7195147B2 (en) 2016-05-16 2022-12-23 アクセス ツー アドバンスト ヘルス インスティチュート PEGylated liposomes and methods of use
US11344619B2 (en) 2016-05-16 2022-05-31 Access To Advanced Health Institute Formulation containing TLR agonist and methods of use
IL311086A (en) 2016-06-01 2024-04-01 Access To Advanced Health Inst Nanoalum particles containing a sizing agent
EP3638207A1 (en) 2017-06-15 2020-04-22 Infectious Disease Research Institute Nanostructured lipid carriers and stable emulsions and uses thereof
US20200276299A1 (en) 2017-09-08 2020-09-03 Infectious Disease Research Institute Liposomal formulations comprising saponin and methods of use
CN114340665A (en) 2019-05-25 2022-04-12 传染病研究所 Compositions and methods for spray drying adjuvant vaccine emulsions
US20230310323A1 (en) 2020-09-04 2023-10-05 Access To Advanced Health Institute Co-lyophilized rna and nanostructured lipid carrier
WO2024052882A1 (en) 2022-09-09 2024-03-14 Access To Advanced Health Institute Immunogenic vaccine composition incorporating a saponin

Family Cites Families (10)

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JPS57106626A (en) * 1980-12-22 1982-07-02 Teijin Ltd Cytotoxic protein complex and its preparation
US4455296A (en) * 1982-02-02 1984-06-19 Board Of Regents, The University Of Texas System Hybrid cell lines producing monoclonal antibodies directed against Haemophilus influenzae
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NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens
EP0320942A3 (en) * 1987-12-18 1989-10-04 American Cyanamid Company Novel polysaccharides novel macromolecular conjugates of the polysaccharides
CA2038581A1 (en) * 1990-03-20 1991-09-21 Martin Muller Seroreactive epitopes of human papillomavirus (hpv) 16 proteins
EP1298211B1 (en) * 1991-07-19 2006-07-12 The University Of Queensland Polynucleotide segment of HPV16 Genome

Also Published As

Publication number Publication date
LU91398I2 (en) 2008-02-14
LU91396I2 (en) 2008-02-14
NL300321I1 (en) 2008-03-03
LU91394I2 (en) 2008-02-14
DE69334192D1 (en) 2008-01-24
DE122007000094I1 (en) 2008-03-27
NL300315I2 (en) 2008-03-03
NL300315I1 (en) 2008-02-01
AU1135295A (en) 1996-02-08
EP0647140A1 (en) 1995-04-12
NL300319I1 (en) 2008-03-03
WO1994000152A1 (en) 1994-01-06
AU697743B2 (en) 1998-10-15
DK0647140T3 (en) 2008-02-04
DE122007000098I1 (en) 2008-03-27
NL300322I1 (en) 2008-03-03
AU697743C (en) 2007-06-14
LU91400I2 (en) 2008-02-14
DE122007000096I1 (en) 2008-03-27
LU91397I2 (en) 2008-02-14
FR07C0073I1 (en) 2008-01-02
NL300318I2 (en) 2008-03-03
US8012679B1 (en) 2011-09-06
DE122007000100I1 (en) 2008-03-27
US20020068326A1 (en) 2002-06-06
DE69334192T2 (en) 2008-12-04
DE122007000099I1 (en) 2008-03-27
NL300320I1 (en) 2008-03-03
DE122007000095I1 (en) 2008-03-27
LU91399I2 (en) 2008-02-14
LU91395I2 (en) 2008-02-14
NL300316I1 (en) 2008-02-01
EP1835029A1 (en) 2007-09-19
DE122007000097I1 (en) 2008-03-27
ATE380871T1 (en) 2007-12-15
DE122007000101I1 (en) 2008-03-27
PT647140E (en) 2007-12-27
ES2294778T3 (en) 2008-04-01
NL300318I1 (en) 2008-02-01
EP0647140A4 (en) 1997-03-19
EP0647140B1 (en) 2007-12-12
NL300317I1 (en) 2008-02-01
LU91393I2 (en) 2008-02-14

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