FR07C0057I1 - - Google Patents
Info
- Publication number
- FR07C0057I1 FR07C0057I1 FR07C0057C FR07C0057I1 FR 07C0057 I1 FR07C0057 I1 FR 07C0057I1 FR 07C0057 C FR07C0057 C FR 07C0057C FR 07C0057 I1 FR07C0057 I1 FR 07C0057I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C271/36—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9722817.5A GB9722817D0 (en) | 1997-10-29 | 1997-10-29 | Novel compounds |
| GBGB9813689.8A GB9813689D0 (en) | 1998-06-25 | 1998-06-25 | Novel compounds |
| PCT/GB1998/003211 WO1999021855A1 (en) | 1997-10-29 | 1998-10-27 | Pleuromutilin derivatives as antimicrobials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR07C0057I1 true FR07C0057I1 (en) | 2007-12-14 |
| FR07C0057I2 FR07C0057I2 (en) | 2008-05-16 |
Family
ID=26312507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR07C0057C Active FR07C0057I2 (en) | 1997-10-29 | 2007-11-09 | PLEUROMUTILINE DERIVATIVES USED AS ANTIMICROBIAL AGENTS |
Country Status (36)
| Country | Link |
|---|---|
| US (3) | US6281226B1 (en) |
| EP (3) | EP1028961B3 (en) |
| JP (2) | JP4227729B2 (en) |
| KR (1) | KR100538721B1 (en) |
| CN (1) | CN1205211C (en) |
| AR (1) | AR015987A1 (en) |
| AT (2) | ATE525373T1 (en) |
| AU (1) | AU742167C (en) |
| BR (1) | BR9814747B1 (en) |
| CA (1) | CA2307551C (en) |
| CO (1) | CO5021129A1 (en) |
| CY (2) | CY2007028I2 (en) |
| CZ (1) | CZ298543B6 (en) |
| DE (2) | DE69826704T3 (en) |
| DK (2) | DK1028961T5 (en) |
| DZ (1) | DZ2634A1 (en) |
| EG (1) | EG24177A (en) |
| ES (2) | ES2229538T7 (en) |
| FR (1) | FR07C0057I2 (en) |
| HK (1) | HK1031376A1 (en) |
| HU (2) | HU229792B1 (en) |
| IL (2) | IL135811A0 (en) |
| LU (1) | LU91372I2 (en) |
| MY (1) | MY130665A (en) |
| NL (1) | NL300304I2 (en) |
| NO (3) | NO327392B1 (en) |
| NZ (1) | NZ504203A (en) |
| PE (1) | PE123299A1 (en) |
| PL (2) | PL197672B1 (en) |
| PT (2) | PT1028961E (en) |
| SI (2) | SI1028961T1 (en) |
| TR (1) | TR200001203T2 (en) |
| TW (1) | TWI232861B (en) |
| UY (1) | UY25225A1 (en) |
| WO (1) | WO1999021855A1 (en) |
| ZA (1) | ZA989767B (en) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY25225A1 (en) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | PLEUROMUTILINE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS |
| WO2000027790A1 (en) * | 1998-11-11 | 2000-05-18 | Smithkline Beecham P.L.C. | Mutilin compounds |
| GB9912657D0 (en) * | 1999-06-01 | 1999-07-28 | Smithkline Beecham Plc | Novel compounds |
| GB9918037D0 (en) * | 1999-07-30 | 1999-09-29 | Biochemie Gmbh | Organic compounds |
| GB9919839D0 (en) * | 1999-08-20 | 1999-10-27 | Smithkline Beecham Plc | Novel compounds |
| US6972297B2 (en) | 2000-04-04 | 2005-12-06 | Smithkline Beecham P.L.C. | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use |
| GB0017031D0 (en) | 2000-07-11 | 2000-08-30 | Biochemie Gmbh | Antimicrobials |
| GB0017073D0 (en) * | 2000-07-11 | 2000-08-30 | Univ London | Microorganism |
| PE20020676A1 (en) * | 2000-09-13 | 2002-08-27 | Biochemie Gmbh | MUTILIN COMPOUNDS AS ANTIBACTERIAL |
| GB0024811D0 (en) | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| GB0027705D0 (en) * | 2000-11-11 | 2000-12-27 | S P A | Novel compounds |
| FR2835186B1 (en) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | NOVEL HETEROCYCLIC COMPOUNDS ACTIVE AS BETA-LACTAMASES INHIBITORS |
| GB0207495D0 (en) * | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
| US7612103B2 (en) * | 2002-07-24 | 2009-11-03 | Nabriva Therapeutics Ag | Pleuromutilin derivatives as antimicrobials |
| GB0218578D0 (en) * | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
| GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
| DE602004024417D1 (en) | 2003-09-03 | 2010-01-14 | Glaxo Group Ltd | NEW METHOD FOR THE PRODUCTION OF PLEUROMUTILINE DERIVATIVES |
| JP2007537261A (en) * | 2004-05-13 | 2007-12-20 | グラクソ グループ リミテッド | Muscarinic acetylcholine receptor antagonist |
| GB0504314D0 (en) * | 2005-03-02 | 2005-04-06 | Glaxo Group Ltd | Novel polymorph |
| JP2008534444A (en) * | 2005-03-10 | 2008-08-28 | スミスクライン・ビーチャム・コーポレイション | New method |
| TW200730488A (en) * | 2005-06-27 | 2007-08-16 | Nabriva Therapeutics Forschungs Gmbh | Organic compounds |
| GB0513058D0 (en) * | 2005-06-27 | 2005-08-03 | Sandoz Ag | Organic compounds |
| WO2007037518A1 (en) * | 2005-09-29 | 2007-04-05 | Dainippon Sumitomo Pharma Co., Ltd. | Mutilin derivative and pharmaceutical composition containing the same |
| WO2007079173A2 (en) * | 2005-12-30 | 2007-07-12 | Emergent Biosolutions Inc. | Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents |
| AU2008212171A1 (en) | 2007-02-09 | 2008-08-14 | Astellas Pharma Inc. | Aza-bridged-ring compound |
| WO2008117796A1 (en) * | 2007-03-28 | 2008-10-02 | Dainippon Sumitomo Pharma Co., Ltd. | Novel mutilin derivatives |
| EP2149571A4 (en) | 2007-05-24 | 2010-09-01 | Kyorin Seiyaku Kk | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| US20090076071A1 (en) * | 2007-09-13 | 2009-03-19 | Protia, Llc | Deuterium-enriched retapamulin |
| TW200936582A (en) * | 2007-11-26 | 2009-09-01 | Teva Pharma | Amorphous retapamulin and processes for preparation thereof |
| US20090149655A1 (en) * | 2007-12-05 | 2009-06-11 | Lilach Hedvati | Process for the preparation of Retapamulin and its intermediates |
| US8278313B2 (en) | 2008-03-11 | 2012-10-02 | Abbott Laboratories | Macrocyclic spiro pyrimidine derivatives |
| US8436005B2 (en) | 2008-04-03 | 2013-05-07 | Abbott Laboratories | Macrocyclic pyrimidine derivatives |
| WO2010056855A1 (en) * | 2008-11-13 | 2010-05-20 | Teva Pharmaceutical Industries Ltd. | Preparation of retapamulin via its pleuromutilin-thiol precursor |
| WO2010100720A1 (en) * | 2009-03-03 | 2010-09-10 | 独立行政法人放射線医学総合研究所 | Reagent for measurement of cholinesterase activity |
| SG177523A1 (en) | 2009-07-14 | 2012-02-28 | Albany Molecular Res Inc | 5-ht3 receptor modulators, methods of making, and use thereof |
| CN102344397B (en) * | 2011-08-23 | 2013-09-04 | 浙江升华拜克生物股份有限公司 | Method for purifying valnemulin hydrochloride |
| CN103626693B (en) * | 2012-08-28 | 2016-09-14 | 中国科学院上海药物研究所 | One class pleuromutilin derivative, its pharmaceutical composition and synthetic method thereof and purposes |
| CN103709093B (en) * | 2012-09-28 | 2016-06-08 | 山东亨利医药科技有限责任公司 | The pleuromulins antibiotic containing and encircle |
| EP3689219B1 (en) | 2014-07-21 | 2023-08-30 | EndoChoice, Inc. | Multi-focal, multi-camera endoscope systems |
| WO2017151489A1 (en) | 2016-03-02 | 2017-09-08 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| CN113845536A (en) * | 2016-03-02 | 2021-12-28 | 比尔及梅琳达盖茨基金会 | Boron-containing small molecules |
| US10874679B2 (en) | 2016-03-02 | 2020-12-29 | Bill & Melinda Gates Foundation | Boron-containing small molecules |
| CN106496085B (en) * | 2016-09-21 | 2018-01-26 | 盐城市舜宝化工有限公司 | The midbody compound of synthetic hydrochloric acid valnemulin and the preparation method of valnemulin hydrochloride |
| TWI762573B (en) | 2017-02-10 | 2022-05-01 | 奧地利商納畢瓦治療有限責任公司 | Purification of pleuromutilin |
| CN111574395B (en) * | 2020-06-18 | 2021-07-02 | 华南农业大学 | Pleuromutilin derivative with amide side chain, preparation and application thereof |
| AT523646B1 (en) | 2020-07-21 | 2021-10-15 | Gerd Dr Ascher | Pharmaceutical compounds, their use alone or in combination, for prophylaxis and local initial therapy in bacterial and viral infections, in particular coronaviruses |
| US11155514B1 (en) * | 2020-12-19 | 2021-10-26 | Shaanxi University Of Science And Technology | Pleuromulin acitretin ester with antibacterial activity and a method of preparing the same |
| US11332430B1 (en) * | 2021-01-25 | 2022-05-17 | Xi'an Taikomed Pharmaceutical Technology Co., Ltd. | Pleuromulin lauric acid ester with antibacterial activity and a method of preparing the same |
| CN112919463B (en) * | 2021-04-09 | 2021-10-26 | 南京理工大学 | Activated carbon prepared from tiamulin waste salt and preparation method thereof |
| CN113121355B (en) * | 2021-04-13 | 2023-05-09 | 西安康诺化工有限公司 | Pleuromutilin rhein and preparation method and application thereof |
| CN114736194A (en) * | 2022-03-29 | 2022-07-12 | 中牧实业股份有限公司 | Pleuromutilin derivative containing pyridine quaternary ammonium salt side chain and having anti-pathogenic microorganism activity and preparation method and application thereof |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060542A (en) * | 1969-07-25 | 1977-11-29 | Biochemie Gesellschaft M.B.H. | 14-Desoxy-14 thiocyanato-acetoxy-mutilin |
| US4208326A (en) | 1971-10-05 | 1980-06-17 | Sandoz Ltd. | Pleuromutilin esters |
| BE789629A (en) * | 1971-10-05 | 1973-04-03 | Sandoz Sa | NEW DERIVATIVES OF PLEUROMUTILINE, THEIR PREPARATION AND THERAPEUTIC APPLICATION |
| CH575375A5 (en) | 1972-05-25 | 1976-05-14 | Sandoz Ag | |
| US3919290A (en) | 1972-10-03 | 1975-11-11 | Sandoz Ltd | Substituted 14-desoxy-mutilins |
| US4032530A (en) | 1971-10-05 | 1977-06-28 | Sandoz Ltd. | Certain pleuromutilins |
| CH593912A5 (en) | 1972-07-07 | 1977-12-30 | Sandoz Ag | Pleuromutilin derivs. - prepd. by acylating derivs. contg. a (4)-hydroxyalkyl-(1)-piperazinyl gp. |
| DE2404046C3 (en) | 1974-01-29 | 1984-07-26 | Henkel KGaA, 4000 Düsseldorf | Use of polymers containing carboxyl or carboxylate and hydroxyl groups as skin moisturizers |
| US3987194A (en) | 1975-05-12 | 1976-10-19 | E. R. Squibb & Sons, Inc. | Use of pleuromutilin derivatives for the treatment of swine dysentery |
| CH619450A5 (en) | 1976-01-15 | 1980-09-30 | Sandoz Ag | |
| US4130709A (en) | 1977-12-08 | 1978-12-19 | Eli Lilly And Company | Pleuromutilin glycoside derivatives |
| GB2025930B (en) | 1978-06-01 | 1983-02-09 | Sandoz Ltd | Process for the production of pleuromutilin derivatives |
| EP0013768B1 (en) * | 1979-01-12 | 1984-02-01 | Sandoz Ag | New pleuromutilin derivatives, their production and pharmaceutical compositions containing them |
| ZA80175B (en) * | 1979-01-12 | 1981-08-26 | Sandoz Ltd | New pleuromutilin derivatives, their production and use |
| FR2502951B1 (en) | 1981-04-06 | 1985-12-06 | Sandoz Sa | TOPICAL PHARMACEUTICAL COMPOSITIONS IN THE FORM OF A MICRO-EMULSION |
| EP0153277B1 (en) * | 1984-02-17 | 1987-08-26 | Sandoz Ag | Pleuromutilin derivatives, process for their preparation and their use |
| DE3405632A1 (en) * | 1984-02-17 | 1985-08-22 | Sandoz-Patent-GmbH, 7850 Lörrach | Novel pleuromutilin derivatives, processes for their preparation, and their use |
| AT400674B (en) | 1991-07-24 | 1996-02-26 | Biochemie Gmbh | PHARMACEUTICAL PLEUROMUTILIN PREPARATION |
| GB9201751D0 (en) | 1992-01-28 | 1992-03-11 | Smithkline Beecham Plc | Compounds |
| AT397654B (en) | 1992-05-04 | 1994-06-27 | Biochemie Gmbh | NEW PLEUROMUTIL DERIVATIVES, THEIR USE AND METHOD FOR THEIR PRODUCTION |
| AU4432496A (en) | 1994-12-23 | 1996-07-19 | Dr. Karl Thomae Gmbh | Piperazine derivatives, medicaments containing the same, their use and process for preparing the same |
| CN1214039A (en) * | 1996-01-03 | 1999-04-14 | 史密斯克莱·比奇曼公司 | Carbamoyloxy derivatives of mutiline and their use as antibacterials |
| HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| KR20000048812A (en) | 1996-10-01 | 2000-07-25 | 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 | Use of Mupirocin for the Manufacture of a Medicament for the Treatment of Bacterial Infections Associated with Colonisation of the Nasopharynx by Pathogenic Organisms |
| UY25225A1 (en) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | PLEUROMUTILINE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS |
| DE602004024417D1 (en) | 2003-09-03 | 2010-01-14 | Glaxo Group Ltd | NEW METHOD FOR THE PRODUCTION OF PLEUROMUTILINE DERIVATIVES |
| GB0504314D0 (en) | 2005-03-02 | 2005-04-06 | Glaxo Group Ltd | Novel polymorph |
-
1996
- 1996-05-07 UY UY25225A patent/UY25225A1/en not_active IP Right Cessation
-
1998
- 1998-10-27 EP EP98950202A patent/EP1028961B3/en not_active Expired - Lifetime
- 1998-10-27 DE DE69826704T patent/DE69826704T3/en not_active Expired - Lifetime
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2000
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2001
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2007
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