FI980341A0 - 2-oxy-indole derivatives - Google Patents

2-oxy-indole derivatives

Info

Publication number
FI980341A0
FI980341A0 FI980341A FI980341A FI980341A0 FI 980341 A0 FI980341 A0 FI 980341A0 FI 980341 A FI980341 A FI 980341A FI 980341 A FI980341 A FI 980341A FI 980341 A0 FI980341 A0 FI 980341A0
Authority
FI
Finland
Prior art keywords
oxy
indole derivatives
derivatives
vasopressin
sulphonyl
Prior art date
Application number
FI980341A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI980341L (en
FI980341A7 (en
Inventor
Loic Foulon
Georges Garcia
Dino Nisato
Richard Roux
Claudine Serradeil-Legal
Gerard Valette
Jean Wagnon
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Priority to FI980341A priority Critical patent/FI980341A0/en
Publication of FI980341L publication Critical patent/FI980341L/en
Publication of FI980341A7 publication Critical patent/FI980341A7/en
Publication of FI980341A0 publication Critical patent/FI980341A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C07D209/92—Naphthostyrils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

N-sulphonyl-2-oxoindole derivatives of formula (I), and any salts thereof, preparation thereof and pharmaceutical compositions containing said derivatives. These compounds have an affinity for vasopressin and/or ocytocin receptors.
FI980341A 1992-01-30 1993-01-28 2-oxy-indole derivatives FI980341A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI980341A FI980341A0 (en) 1992-01-30 1993-01-28 2-oxy-indole derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9201034A FR2686878B1 (en) 1992-01-30 1992-01-30 DERIVATIVES OF N-SULFONYL OXO-2 INDOLE, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.
PCT/FR1993/000093 WO1993015051A1 (en) 1992-01-30 1993-01-28 N-sulphonyl-2-oxoindole derivatives having affinity for vasopressin and/or ocytocin receptors
FI934274A FI934274L (en) 1992-01-30 1993-01-28 N-SULFONYL-2-OXI-INDOLDERIVAT, DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE FARMACEUTISKA KOMPOSITIONER
FI980341A FI980341A0 (en) 1992-01-30 1993-01-28 2-oxy-indole derivatives

Publications (3)

Publication Number Publication Date
FI980341L FI980341L (en) 1998-02-13
FI980341A7 FI980341A7 (en) 1998-02-13
FI980341A0 true FI980341A0 (en) 1998-02-13

Family

ID=9426168

Family Applications (2)

Application Number Title Priority Date Filing Date
FI980341A FI980341A0 (en) 1992-01-30 1993-01-28 2-oxy-indole derivatives
FI934274A FI934274L (en) 1992-01-30 1993-01-28 N-SULFONYL-2-OXI-INDOLDERIVAT, DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE FARMACEUTISKA KOMPOSITIONER

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI934274A FI934274L (en) 1992-01-30 1993-01-28 N-SULFONYL-2-OXI-INDOLDERIVAT, DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE FARMACEUTISKA KOMPOSITIONER

Country Status (20)

Country Link
EP (1) EP0581939B1 (en)
JP (1) JPH06507182A (en)
AT (1) ATE180773T1 (en)
AU (1) AU662960B2 (en)
BR (1) BR9303993A (en)
CA (1) CA2107348A1 (en)
CZ (1) CZ203793A3 (en)
DE (1) DE69325130D1 (en)
FI (2) FI980341A0 (en)
FR (1) FR2686878B1 (en)
HU (1) HUT68642A (en)
IL (1) IL104559A0 (en)
MX (1) MX9300498A (en)
NO (1) NO180538C (en)
NZ (1) NZ249158A (en)
RU (1) RU2135469C1 (en)
SK (1) SK105393A3 (en)
TW (1) TW239126B (en)
WO (1) WO1993015051A1 (en)
ZA (1) ZA93649B (en)

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FR2708608B1 (en) * 1993-07-30 1995-10-27 Sanofi Sa N-sulfonylbenzimidazolone derivatives, their preparation, pharmaceutical compositions containing them.
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FR2722190B1 (en) * 1994-07-05 1996-10-04 Sanofi Sa 1-BENZYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO1996036611A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
FR2740136B1 (en) * 1995-10-24 1998-01-09 Sanofi Sa INDOLIN-2-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Also Published As

Publication number Publication date
ATE180773T1 (en) 1999-06-15
SK105393A3 (en) 1994-08-10
FR2686878A1 (en) 1993-08-06
FI980341L (en) 1998-02-13
EP0581939B1 (en) 1999-06-02
FI980341A7 (en) 1998-02-13
BR9303993A (en) 1994-08-02
NO933482D0 (en) 1993-09-29
RU2135469C1 (en) 1999-08-27
EP0581939A1 (en) 1994-02-09
MX9300498A (en) 1994-07-29
NO180538C (en) 1997-05-07
FI934274A7 (en) 1993-09-29
HUT68642A (en) 1995-07-28
CZ203793A3 (en) 1994-04-13
CA2107348A1 (en) 1993-07-31
NZ249158A (en) 1996-02-27
AU662960B2 (en) 1995-09-21
ZA93649B (en) 1993-09-02
HU9302762D0 (en) 1993-12-28
NO933482L (en) 1993-11-29
AU3504393A (en) 1993-09-01
WO1993015051A1 (en) 1993-08-05
NO180538B (en) 1997-01-27
FR2686878B1 (en) 1995-06-30
JPH06507182A (en) 1994-08-11
FI934274A0 (en) 1993-09-29
FI934274L (en) 1993-09-29
DE69325130D1 (en) 1999-07-08
IL104559A0 (en) 1993-05-13
TW239126B (en) 1995-01-21

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