FI970765A - Dinukleotidi- ja oligonukleotidianalogien välituotteet - Google Patents
Dinukleotidi- ja oligonukleotidianalogien välituotteet Download PDFInfo
- Publication number
- FI970765A FI970765A FI970765A FI970765A FI970765A FI 970765 A FI970765 A FI 970765A FI 970765 A FI970765 A FI 970765A FI 970765 A FI970765 A FI 970765A FI 970765 A FI970765 A FI 970765A
- Authority
- FI
- Finland
- Prior art keywords
- dinucleotide
- intermediates
- oligonucleotide analogs
- oligonucleotide
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9417746A GB9417746D0 (en) | 1994-09-03 | 1994-09-03 | Chemical compounds |
| PCT/GB1995/001955 WO1996008503A1 (en) | 1994-09-03 | 1995-08-17 | Intermediates for dinucleotide and oligonucleotide analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI970765A0 FI970765A0 (fi) | 1997-02-24 |
| FI970765A true FI970765A (fi) | 1997-04-25 |
Family
ID=10760791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970765A FI970765A (fi) | 1994-09-03 | 1997-02-24 | Dinukleotidi- ja oligonukleotidianalogien välituotteet |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5952478A (fi) |
| EP (1) | EP0778843A1 (fi) |
| JP (1) | JPH10506621A (fi) |
| AU (1) | AU695607B2 (fi) |
| CA (1) | CA2198900A1 (fi) |
| FI (1) | FI970765A (fi) |
| GB (1) | GB9417746D0 (fi) |
| HU (1) | HUT76857A (fi) |
| NO (1) | NO970870L (fi) |
| WO (1) | WO1996008503A1 (fi) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879700A (en) * | 1991-10-15 | 1999-03-09 | Hostetler; Karl Y. | Nucleoside analogue phosphates for topical use |
| US6639061B1 (en) | 1999-07-07 | 2003-10-28 | Isis Pharmaceuticals, Inc. | C3′-methylene hydrogen phosphonate oligomers and related compounds |
| GB9604669D0 (en) | 1996-03-05 | 1996-05-01 | Ciba Geigy Ag | Chemical compounds |
| GB9612600D0 (en) | 1996-06-13 | 1996-08-21 | Ciba Geigy Ag | Chemical compounds |
| US6414135B1 (en) | 1999-07-07 | 2002-07-02 | Isis Pharmaceuticals, Inc. | C3′-methylene hydrogen phosphonate monomers and related compounds |
| US8324179B2 (en) * | 2007-02-09 | 2012-12-04 | Gilead Sciences, Inc. | Nucleoside analogs for antiviral treatment |
| CN103209987B (zh) | 2010-09-22 | 2017-06-06 | 艾丽奥斯生物制药有限公司 | 取代的核苷酸类似物 |
| AU2012358804B2 (en) | 2011-12-22 | 2018-04-19 | Alios Biopharma, Inc. | Substituted phosphorothioate nucleotide analogs |
| WO2013142124A1 (en) | 2012-03-21 | 2013-09-26 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
| EP2827876A4 (en) | 2012-03-22 | 2015-10-28 | Alios Biopharma Inc | PHARMACEUTICAL COMBINATIONS WITH A THIONUCLEOTIDE ANALOG |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3307744A1 (de) * | 1983-03-04 | 1984-09-06 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | 2'-desoxy-3'-phosphonylmethyl-nucleoside |
| DE4037363A1 (de) * | 1990-04-09 | 1991-10-10 | Europ Lab Molekularbiolog | 2-0-alkylnukleotide sowie polymere, die solche nukleotide enthalten |
| US5378825A (en) * | 1990-07-27 | 1995-01-03 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogs |
| GB9304618D0 (en) * | 1993-03-06 | 1993-04-21 | Ciba Geigy Ag | Chemical compounds |
| GB9311682D0 (en) * | 1993-06-05 | 1993-07-21 | Ciba Geigy Ag | Chemical compounds |
-
1994
- 1994-09-03 GB GB9417746A patent/GB9417746D0/en active Pending
-
1995
- 1995-08-17 AU AU32296/95A patent/AU695607B2/en not_active Ceased
- 1995-08-17 EP EP95928582A patent/EP0778843A1/en not_active Withdrawn
- 1995-08-17 HU HU9701515A patent/HUT76857A/hu unknown
- 1995-08-17 WO PCT/GB1995/001955 patent/WO1996008503A1/en not_active Application Discontinuation
- 1995-08-17 US US08/793,725 patent/US5952478A/en not_active Expired - Fee Related
- 1995-08-17 JP JP8509970A patent/JPH10506621A/ja active Pending
- 1995-08-17 CA CA002198900A patent/CA2198900A1/en not_active Abandoned
-
1997
- 1997-02-24 FI FI970765A patent/FI970765A/fi unknown
- 1997-02-26 NO NO970870A patent/NO970870L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU695607B2 (en) | 1998-08-20 |
| GB9417746D0 (en) | 1994-10-19 |
| US5952478A (en) | 1999-09-14 |
| NO970870L (no) | 1997-04-17 |
| EP0778843A1 (en) | 1997-06-18 |
| WO1996008503A1 (en) | 1996-03-21 |
| FI970765A0 (fi) | 1997-02-24 |
| HUT76857A (en) | 1997-12-29 |
| JPH10506621A (ja) | 1998-06-30 |
| AU3229695A (en) | 1996-03-29 |
| CA2198900A1 (en) | 1996-03-21 |
| NO970870D0 (no) | 1997-02-26 |
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