FI962948A - Method for dissolving sparingly soluble pharmaceutically active substances - Google Patents
Method for dissolving sparingly soluble pharmaceutically active substances Download PDFInfo
- Publication number
- FI962948A FI962948A FI962948A FI962948A FI962948A FI 962948 A FI962948 A FI 962948A FI 962948 A FI962948 A FI 962948A FI 962948 A FI962948 A FI 962948A FI 962948 A FI962948 A FI 962948A
- Authority
- FI
- Finland
- Prior art keywords
- active substances
- pharmaceutically active
- sparingly soluble
- soluble pharmaceutically
- dissolving
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18557694A | 1994-01-24 | 1994-01-24 | |
PCT/US1995/001018 WO1995019759A1 (en) | 1994-01-24 | 1995-01-24 | Process for solubilizing difficultly soluble pharmaceutical actives |
Publications (2)
Publication Number | Publication Date |
---|---|
FI962948A true FI962948A (en) | 1996-07-23 |
FI962948A0 FI962948A0 (en) | 1996-07-23 |
Family
ID=22681571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI962948A FI962948A0 (en) | 1994-01-24 | 1996-07-23 | Process for dissolving difficult soluble pharmaceutically active substances |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0741560A1 (en) |
JP (1) | JPH09508128A (en) |
CN (1) | CN1138827A (en) |
AU (1) | AU706890B2 (en) |
BR (1) | BR9506564A (en) |
CA (1) | CA2181241C (en) |
CZ (1) | CZ210496A3 (en) |
FI (1) | FI962948A0 (en) |
MX (1) | MX9602955A (en) |
NO (1) | NO963052L (en) |
NZ (1) | NZ279443A (en) |
PL (1) | PL315635A1 (en) |
SK (1) | SK96196A3 (en) |
WO (1) | WO1995019759A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998058637A1 (en) * | 1996-06-20 | 1998-12-30 | Mcneil-Ppc | Acetaminophen and diphenhydramine analgesics |
ZA975444B (en) * | 1996-06-20 | 1998-12-21 | Mcneil Ppc Inc | Acetaminophen and meclizine hydrochloride analgesics |
FR2751875B1 (en) * | 1996-08-05 | 1998-12-24 | Scr Newpharm | NOVEL STABLE LIQUID FORMULATIONS BASED ON PARACETAMOL AND THEIR METHOD OF PREPARATION |
US5763449A (en) * | 1996-08-07 | 1998-06-09 | Ascent Pediatrics, Inc. | Pleasant-tasting aqueous liquid composition of a bitter-tasting drug |
DE69940769D1 (en) * | 1998-01-20 | 2009-06-04 | Applied Analytical Ind Inc | ORAL LIQUID COMPOSITIONS |
US6365180B1 (en) * | 1998-01-20 | 2002-04-02 | Glenn A. Meyer | Oral liquid compositions |
US20020086878A1 (en) * | 1999-01-11 | 2002-07-04 | Douglas Joseph Dobrozsi | Compositions having improved stability |
US20020082307A1 (en) * | 1999-01-11 | 2002-06-27 | Dobrozsi Douglas Joseph | Compositions having improved stability |
US6846495B2 (en) | 1999-01-11 | 2005-01-25 | The Procter & Gamble Company | Compositions having improved delivery of actives |
US6211246B1 (en) * | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
FR2796843B1 (en) * | 1999-07-29 | 2003-05-09 | So Ge Val Sa | CONCENTRATED AND STABILIZED ANTIPYRETIC COMPOSITION FOR VETERINARY USE INTENDED TO BE INCORPORATED IN ANIMAL FEEDING AS WELL AS A METHOD OF INCORPORATING THIS COMPOSITION INTO ANIMAL BEVERAGE WATER |
US6251426B1 (en) * | 1999-09-02 | 2001-06-26 | Banner Pharmacaps, Inc. | Ibuprofen-containing softgels |
DE10011032A1 (en) * | 2000-03-07 | 2001-09-13 | Bayer Ag | Stable solutions of acetylsalicylic acid in mixture of organic solvent and water, useful for topical treatment of pain, especially pain associated with herpes zoster |
KR20020069387A (en) * | 2001-02-26 | 2002-09-04 | 진양제약주식회사 | Mixing method of composition containing doxylamine succinate and soft capsule preparation containing the composition |
JP2004538309A (en) * | 2001-07-31 | 2004-12-24 | ワイエス | Sucralose formulation to mask unpleasant taste |
US7101572B2 (en) * | 2001-12-07 | 2006-09-05 | Unilab Pharmatech, Ltd. | Taste masked aqueous liquid pharmaceutical composition |
CN100379406C (en) * | 2003-09-22 | 2008-04-09 | 北京德众万全药物技术开发有限公司 | Method for preparing tiny pellets of difficult soluble drugs and formulation containing the pellets |
CA2627292C (en) * | 2005-10-26 | 2012-04-17 | Banner Pharmacaps, Inc. | Hydrophilic vehicle-based dual controlled release matrix system |
DE102005053066A1 (en) | 2005-11-04 | 2007-05-10 | Basf Ag | Use of copolymers as solubilizers for sparingly water-soluble compounds |
EP1962908A2 (en) * | 2005-12-09 | 2008-09-03 | Basf Se | Use of polyvinyl lactam-polyoxyalkylene block copolymers as solubilisers for poorly water-soluble compounds |
US8637076B2 (en) | 2006-06-01 | 2014-01-28 | Cima Labs Inc. | Prednisolone salt formulations |
JP2008184430A (en) * | 2007-01-30 | 2008-08-14 | Ss Pharmaceut Co Ltd | Soft capsule |
CA2690488C (en) * | 2010-01-19 | 2013-06-11 | Accucaps Industries Limited | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
CA2690490C (en) * | 2010-01-19 | 2012-06-26 | Accucaps Industries Limited | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
EP3158991B1 (en) | 2010-01-28 | 2021-03-17 | Eagle Pharmaceuticals, Inc. | Formulations of bendamustine |
WO2013142359A1 (en) | 2012-03-20 | 2013-09-26 | Eagle Pharmaceuticals, Inc. | Method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration |
DK2827862T3 (en) | 2012-03-20 | 2024-02-12 | Eagle Pharmaceuticals Inc | FORMULATIONS OF BENDAMUSTINE |
KR101695580B1 (en) * | 2013-02-28 | 2017-01-13 | 화이자 인코포레이티드 | Enhanced stability of novel liquid compositions |
GB201506755D0 (en) * | 2015-04-21 | 2015-06-03 | Reckitt Benckiser Llc | Novel pharmaceutical formulation |
TWI586379B (en) | 2015-06-29 | 2017-06-11 | 永信藥品工業股份有限公司 | Method of preparing very slightly soluble drug with solid dosage form |
WO2017062997A1 (en) | 2015-10-09 | 2017-04-13 | Reckitt Benckiser Llc | Pharmaceutical formulation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141961A (en) * | 1991-06-27 | 1992-08-25 | Richrdson-Vicks Inc. | Process for solubilizing difficulty soluble pharmaceutical actives |
-
1995
- 1995-01-24 JP JP7519747A patent/JPH09508128A/en active Pending
- 1995-01-24 EP EP95908124A patent/EP0741560A1/en not_active Withdrawn
- 1995-01-24 CZ CZ962104A patent/CZ210496A3/en unknown
- 1995-01-24 CA CA002181241A patent/CA2181241C/en not_active Expired - Fee Related
- 1995-01-24 WO PCT/US1995/001018 patent/WO1995019759A1/en not_active Application Discontinuation
- 1995-01-24 NZ NZ279443A patent/NZ279443A/en unknown
- 1995-01-24 CN CN95191303.4A patent/CN1138827A/en active Pending
- 1995-01-24 AU AU16075/95A patent/AU706890B2/en not_active Ceased
- 1995-01-24 MX MX9602955A patent/MX9602955A/en unknown
- 1995-01-24 SK SK961-96A patent/SK96196A3/en unknown
- 1995-01-24 BR BR9506564A patent/BR9506564A/en not_active Application Discontinuation
- 1995-01-24 PL PL95315635A patent/PL315635A1/en unknown
-
1996
- 1996-07-22 NO NO963052A patent/NO963052L/en not_active Application Discontinuation
- 1996-07-23 FI FI962948A patent/FI962948A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
SK96196A3 (en) | 1997-03-05 |
NO963052L (en) | 1996-09-24 |
EP0741560A1 (en) | 1996-11-13 |
WO1995019759A1 (en) | 1995-07-27 |
NZ279443A (en) | 1998-04-27 |
BR9506564A (en) | 1997-09-02 |
CA2181241A1 (en) | 1995-07-27 |
MX9602955A (en) | 1997-06-28 |
CZ210496A3 (en) | 1996-12-11 |
FI962948A0 (en) | 1996-07-23 |
CN1138827A (en) | 1996-12-25 |
PL315635A1 (en) | 1996-11-25 |
AU706890B2 (en) | 1999-07-01 |
JPH09508128A (en) | 1997-08-19 |
NO963052D0 (en) | 1996-07-22 |
AU1607595A (en) | 1995-08-08 |
CA2181241C (en) | 2000-04-25 |
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