FI962435A0 - N.N'-bis(2-hydroksibentsyyli)eteenidiamiini-N,N'-dietikkahapon johdannaiset kelatoivina aineina - Google Patents

N.N'-bis(2-hydroksibentsyyli)eteenidiamiini-N,N'-dietikkahapon johdannaiset kelatoivina aineina

Info

Publication number
FI962435A0
FI962435A0 FI962435A FI962435A FI962435A0 FI 962435 A0 FI962435 A0 FI 962435A0 FI 962435 A FI962435 A FI 962435A FI 962435 A FI962435 A FI 962435A FI 962435 A0 FI962435 A0 FI 962435A0
Authority
FI
Finland
Prior art keywords
hydroxybenzyl
ethylenediamine
bis
acid derivatives
chelating agents
Prior art date
Application number
FI962435A
Other languages
English (en)
Swedish (sv)
Other versions
FI962435A (fi
Inventor
Fabrizio Gasparini
Thomas Leutert
David L Farley
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI962435A0 publication Critical patent/FI962435A0/fi
Publication of FI962435A publication Critical patent/FI962435A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms
    • C07D317/40—Vinylene carbonate; Substituted vinylene carbonates

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
FI962435A 1993-12-16 1996-06-12 N.N'-bis(2-hydroksibentsyyli)eteenidiamiini-N,N'-dietikkahapon johdannaiset kelatoivina aineina FI962435A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93810886 1993-12-16
PCT/IB1994/000388 WO1995016663A1 (en) 1993-12-16 1994-12-05 N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives as chelating agents

Publications (2)

Publication Number Publication Date
FI962435A0 true FI962435A0 (fi) 1996-06-12
FI962435A FI962435A (fi) 1996-06-12

Family

ID=8215091

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962435A FI962435A (fi) 1993-12-16 1996-06-12 N.N'-bis(2-hydroksibentsyyli)eteenidiamiini-N,N'-dietikkahapon johdannaiset kelatoivina aineina

Country Status (9)

Country Link
EP (1) EP0734374A1 (fi)
JP (1) JPH09507473A (fi)
CN (1) CN1137267A (fi)
AU (1) AU1033495A (fi)
CA (1) CA2179203A1 (fi)
FI (1) FI962435A (fi)
HU (1) HUT74457A (fi)
NO (1) NO962307L (fi)
WO (1) WO1995016663A1 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026116B1 (en) 1996-04-04 2006-04-11 Bio-Rad Laboratories, Inc. Polymorphisms in the region of the human hemochromatosis gene
US6140305A (en) * 1996-04-04 2000-10-31 Bio-Rad Laboratories, Inc. Hereditary hemochromatosis gene products
AU2958397A (en) * 1996-05-21 1997-12-09 Novartis Ag N,n'-di(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives
US6849399B1 (en) 1996-05-23 2005-02-01 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron misregulation diseases
EP1757614B1 (en) 1997-06-13 2010-03-31 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases
FR2768145B1 (fr) 1997-09-09 1999-10-08 Oreal Nouveaux composes derives d'acide alkylene diamine di- ou tri-acetique, leur procede de preparation, leur utilisation dans des compositions cosmetiques et pharmaceutiques, et compositions les comprenant
TR200002256T2 (tr) 1998-02-04 2001-03-21 University Of Florida Research Foundation, Inc. Demir celatlama tedavisinde N,N' -BIS(2-Hidroksibenzil) etilendiamin-N, N'diasetik asit içeren farmasötikler.
US6646157B2 (en) 1999-12-21 2003-11-11 Geltex Pharmaceuticals, Inc. Method for making HBED
CN109438517B (zh) * 2018-12-27 2021-01-08 北京久杰净化工程技术有限公司 一种与羰基金属核心配位的双功能连接剂的配合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528196A (en) * 1981-02-23 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Chelating agents for the treatment of iron overload
DE69023394T2 (de) * 1989-06-16 1996-07-04 Merck Frosst Canada Inc Chelat-Derivate von atrialnatriurethischem Faktor (ANF).

Also Published As

Publication number Publication date
AU1033495A (en) 1995-07-03
HU9601658D0 (en) 1996-08-28
WO1995016663A1 (en) 1995-06-22
NO962307D0 (no) 1996-06-04
FI962435A (fi) 1996-06-12
CN1137267A (zh) 1996-12-04
HUT74457A (en) 1996-12-30
NO962307L (no) 1996-06-04
CA2179203A1 (en) 1995-06-22
EP0734374A1 (en) 1996-10-02
JPH09507473A (ja) 1997-07-29

Similar Documents

Publication Publication Date Title
NL300181I2 (nl) N-(pyrroloÖÄ2,3-dÖÜpyrimidine-3-ylacyl)-glutaminezuurderivaten.
DE69010714D1 (de) Stückförmiges Waschmittel.
ATA236185A (de) Waesseriges, thixotropes waschmittel
TR199501261A2 (tr) Aminler ve anyonik yüzeyaktif maddeler ihtiva eden deterjan bilesimleri.
MA23136A1 (fr) Composition de nettoyage comprenant des tensio- actifs a courte chaine .
FI954255A0 (fi) 2,9-diamino- ja 2-amino-8-karbaomyyli-4-hydroksi-alkaanihappoamidijohdannaiset
TR26910A (tr) Konsantre, sulu sivi deterjan bilesimleri.
ZA979834B (en) Ethylenediaminetriacetic acid and N-acyl ethylenediaminetriacetic acid silver chelating agents and surfactants.
ATA236085A (de) Waesseriges, thixotropes waschmittel
FI962435A0 (fi) N.N'-bis(2-hydroksibentsyyli)eteenidiamiini-N,N'-dietikkahapon johdannaiset kelatoivina aineina
NL1001517A1 (nl) Koppeling.
AU2456201A (en) N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy
NO913919L (no) Vandig, tiksotropisk vaskemiddelblanding.
NL1001617C2 (nl) Koppeling.
DE59301060D1 (de) Substituierte Aminosäureamide.
FI941149A (fi) 2,4-diamino-3-hydroksikarboksyylihapon johdannaisia
AU2958397A (en) N,n'-di(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives
BR9408162A (pt) Derivados de ácido 2,3,5,6-tetrafluorbenzóico
IT1267492B1 (it) Composizione detergente.
TR199500943A2 (tr) Deterjan bilesimleri.
FI945105A0 (fi) 17alfa- ja 17beta-substituoitu estra-1,3,5(10)-trieeni-3-karboksyylihappo
NL192999B (nl) Koppeling.
Jun et al. Growth-cycle decomposed innovation diffusion model
ES1028019Y (es) Esfera celeste local armilar perfeccionada.
IT8119746A0 (it) N,n'-bis (2-idrossi-e 2,3-diidrossibenzoli)-d,w-di e triami-noalcani come prodotti farmaceutici per chelare il ferro attivi per via orale.

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: NOVARTIS AG

FD Application lapsed