FI961681A - A combination of bisphosphonates and growth hormone secretagogues - Google Patents
A combination of bisphosphonates and growth hormone secretagogues Download PDFInfo
- Publication number
- FI961681A FI961681A FI961681A FI961681A FI961681A FI 961681 A FI961681 A FI 961681A FI 961681 A FI961681 A FI 961681A FI 961681 A FI961681 A FI 961681A FI 961681 A FI961681 A FI 961681A
- Authority
- FI
- Finland
- Prior art keywords
- bisphosphonates
- combination
- growth hormone
- hormone secretagogues
- secretagogues
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13929693A | 1993-10-19 | 1993-10-19 | |
| US25909194A | 1994-06-13 | 1994-06-13 | |
| PCT/US1994/011912 WO1995011029A1 (en) | 1993-10-19 | 1994-10-18 | Combination of bisphosphonates and growth hormone secretagogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI961681A0 FI961681A0 (en) | 1996-04-17 |
| FI961681A true FI961681A (en) | 1996-06-12 |
Family
ID=26837073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI961681A FI961681A (en) | 1993-10-19 | 1996-04-17 | A combination of bisphosphonates and growth hormone secretagogues |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0813414A4 (en) |
| JP (1) | JPH09504525A (en) |
| KR (1) | KR960705575A (en) |
| CN (1) | CN1136278A (en) |
| AU (1) | AU8083694A (en) |
| BG (1) | BG100517A (en) |
| BR (1) | BR9407869A (en) |
| CA (1) | CA2173333A1 (en) |
| CZ (1) | CZ109196A3 (en) |
| FI (1) | FI961681A (en) |
| HU (1) | HUT75224A (en) |
| LV (1) | LV11432B (en) |
| NO (1) | NO961536L (en) |
| PL (1) | PL314003A1 (en) |
| SK (1) | SK49796A3 (en) |
| WO (1) | WO1995011029A1 (en) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686624A (en) * | 1992-01-30 | 1997-11-11 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| US20020111461A1 (en) | 1999-05-21 | 2002-08-15 | Todd C. Somers | Low molecular weight peptidomimetic growth hormone secretagogues |
| US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| ATE288444T1 (en) * | 1995-05-29 | 2005-02-15 | Pfizer | DIPEPTIDES THAT STIMULATE THE RELEASE OF GROWTH HORMONES |
| CA2234817A1 (en) * | 1995-10-27 | 1997-05-01 | Mandana Asgharnejad | Wet granulation formulation of a growth hormone secretagogue |
| US6531314B1 (en) | 1996-12-10 | 2003-03-11 | Merck & Co., Inc. | Growth hormone secretagogue receptor family |
| CA2240186A1 (en) | 1995-12-13 | 1997-06-19 | Merck & Co., Inc. | Assays for growth hormone secretagogue receptors |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| HN1996000101A (en) * | 1996-02-28 | 1997-06-26 | Inc Pfizer | COMBINED THERAPY FOR OSTEOPOROSIS |
| JP2000512274A (en) * | 1996-05-31 | 2000-09-19 | ノボ ノルディスク アクティ―ゼルスカブ | Growth hormone components and bone antiresorptives in the periodic (consistent) treatment of osteoporosis |
| WO1998018815A1 (en) * | 1996-10-25 | 1998-05-07 | Merck & Co., Inc. | Convergent process for the preparation of a growth hormone secretagogue |
| US6376477B2 (en) | 1996-11-25 | 2002-04-23 | Merck & Co., Inc. | Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism |
| GB2324726A (en) * | 1997-05-01 | 1998-11-04 | Merck & Co Inc | Combination Therapy for the Treatment of Osteoporosis |
| ZA987385B (en) * | 1997-08-19 | 2000-04-18 | Lilly Co Eli | Growth hormone secretagogues. |
| US6211174B1 (en) * | 1997-10-31 | 2001-04-03 | Merck & Co., Inc. | Naphtho-fused lactams promote release of growth hormone |
| IT1296495B1 (en) * | 1997-11-21 | 1999-06-25 | Prodotti Antibiotici Spa | USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION |
| US6682908B1 (en) | 1998-07-10 | 2004-01-27 | Merck & Co., Inc. | Mouse growth hormone secretagogue receptor |
| JP2002520011A (en) | 1998-07-13 | 2002-07-09 | メルク・アンド・カンパニー・インコーポレーテッド | Growth hormone secretagogue-related receptors and nucleic acids |
| WO2000009538A2 (en) | 1998-08-10 | 2000-02-24 | Merck & Co., Inc. | Canine growth hormone secretagogue receptor |
| US6639076B1 (en) | 1998-08-18 | 2003-10-28 | Eli Lilly And Company | Growth hormone secretagogues |
| AU2686899A (en) * | 1998-08-18 | 2000-03-14 | Eli Lilly And Company | Growth hormone secretagogues |
| AR013994A1 (en) * | 1998-10-30 | 2001-01-31 | Gador Sa | PROCEDURE AND PREPARATIONS THAT SELECTIVELY MODULATE THE FUNCTION OF THE OSTEOBLASTO FOR THE PREVENTION AND TREATMENT OF FRAGILIZING OSTEOPATHIES. |
| US6416737B1 (en) * | 1998-11-19 | 2002-07-09 | Board Of Trustees Of The University Of Arkansas | Increasing bone strength with selected bisphosphonates |
| US6828331B1 (en) | 1999-02-19 | 2004-12-07 | Eli Lilly And Company | Growth hormone secretagogues |
| WO2000074685A1 (en) * | 1999-06-02 | 2000-12-14 | Sumitomo Pharmaceuticals Co., Ltd. | Oral preparations of etidronate disodium |
| ATE446758T1 (en) | 2000-05-31 | 2009-11-15 | Pfizer Prod Inc | USE OF GROWTH HORMONE SECRETAGOGENES TO PROMOTE DIGESTIVE MOTILITY |
| US6548042B2 (en) | 2000-08-07 | 2003-04-15 | Arstad Erik | Bis-phosphonate compounds |
| ATE297740T1 (en) | 2001-01-23 | 2005-07-15 | Gador Sa | BISPHOSPHONATE-CONTAINING COMPOSITIONS FOR PREVENTING AND/OR CUREING METABOLIC BONE DISEASES, METHOD FOR THE PRODUCTION AND USE OF THESE COMPOSITIONS |
| US7125840B2 (en) | 2001-10-09 | 2006-10-24 | Eli Lilly And Company | Substituted dipeptides as growth hormone secretagogues |
| AU2003220441A1 (en) | 2002-04-09 | 2003-10-27 | Eli Lilly And Company | Dipeptidic growth hormone secretagogues |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| CA2524610C (en) * | 2003-05-07 | 2014-03-25 | Osteologix A/S | Strontium combinations for prophylaxis/treatment of cartilage and/or bone conditions |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| EP2374455A3 (en) | 2004-08-19 | 2012-03-28 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| US7786141B2 (en) | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
| RU2007124373A (en) | 2004-11-29 | 2009-01-10 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | MUSCARINE RECEPTION MODULATORS |
| US7858635B2 (en) | 2005-12-22 | 2010-12-28 | Vertex Pharmaceuticals Incorporated | Spiro compounds as modulators of muscarinic receptors |
| EP1988892A2 (en) | 2006-02-22 | 2008-11-12 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| US8263605B2 (en) | 2006-02-22 | 2012-09-11 | Vertex Pharmaceutical Incorporated | Modulators of muscarinic receptors |
| CU23558A1 (en) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE |
| US7858790B2 (en) | 2006-06-29 | 2010-12-28 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| AU2007284548A1 (en) | 2006-08-15 | 2008-02-21 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| CN101573121A (en) | 2006-08-18 | 2009-11-04 | 弗特克斯药品有限公司 | Modulators of muscarinic receptors |
| CN101657436A (en) | 2007-02-09 | 2010-02-24 | 特兰齐姆制药公司 | Macrocyclic ghrelin receptor modulators and using method thereof |
| US20100099640A1 (en) | 2007-05-04 | 2010-04-22 | Joannes Geuns | Tissue degeneration protection |
| AU2008307440A1 (en) | 2007-10-03 | 2009-04-09 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| WO2013190520A2 (en) | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | Gh-releasing agents in the treatment of vascular stenosis and associated conditions |
| CA2950390C (en) | 2014-05-30 | 2020-09-22 | Pfizer Inc. | Carbonitrile derivatives as selective androgen receptor modulators |
| BR112020024292A2 (en) | 2018-06-06 | 2021-03-02 | Massachusetts Institute Of Technology | circular rna for translation into eukaryotic cells |
| JP2022533796A (en) | 2019-05-22 | 2022-07-25 | マサチューセッツ インスティテュート オブ テクノロジー | Circular RNA compositions and methods |
| CA3160739A1 (en) | 2019-12-04 | 2021-06-10 | Brian Goodman | Circular rna compositions and methods |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU569391B2 (en) * | 1984-04-30 | 1988-01-28 | Procter & Gamble Company, The | Treating osteoporosis |
| AU568433B2 (en) * | 1984-04-30 | 1987-12-24 | Procter & Gamble Company, The | Treating osteoporosis |
| RU2168512C2 (en) * | 1992-12-11 | 2001-06-10 | Мерк Энд Ко., Инк. | Spiropiperidines, methods of their synthesis (variants) |
| US5284841A (en) * | 1993-02-04 | 1994-02-08 | Merck & Co., Inc. | Benzo-fused lactams promote release of growth hormone |
| US5434261A (en) * | 1993-07-26 | 1995-07-18 | Merck & Co., Inc. | Benzo-fused lactams promote release of growth hormone |
| US5545735A (en) * | 1993-10-04 | 1996-08-13 | Merck & Co., Inc. | Benzo-Fused Lactams promote release of growth hormone |
-
1994
- 1994-10-18 KR KR1019960702007A patent/KR960705575A/en not_active Application Discontinuation
- 1994-10-18 EP EP94931923A patent/EP0813414A4/en not_active Withdrawn
- 1994-10-18 CA CA002173333A patent/CA2173333A1/en not_active Abandoned
- 1994-10-18 AU AU80836/94A patent/AU8083694A/en not_active Abandoned
- 1994-10-18 PL PL94314003A patent/PL314003A1/en unknown
- 1994-10-18 CZ CZ961091A patent/CZ109196A3/en unknown
- 1994-10-18 SK SK497-96A patent/SK49796A3/en unknown
- 1994-10-18 CN CN94194311A patent/CN1136278A/en active Pending
- 1994-10-18 HU HU9601013A patent/HUT75224A/en unknown
- 1994-10-18 JP JP7512182A patent/JPH09504525A/en active Pending
- 1994-10-18 BR BR9407869A patent/BR9407869A/en not_active Application Discontinuation
- 1994-10-18 WO PCT/US1994/011912 patent/WO1995011029A1/en not_active Application Discontinuation
-
1996
- 1996-04-17 FI FI961681A patent/FI961681A/en unknown
- 1996-04-18 NO NO961536A patent/NO961536L/en unknown
- 1996-04-18 BG BG100517A patent/BG100517A/en unknown
- 1996-04-23 LV LVP-96-124A patent/LV11432B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995011029A1 (en) | 1995-04-27 |
| BG100517A (en) | 1996-11-29 |
| PL314003A1 (en) | 1996-08-05 |
| SK49796A3 (en) | 1997-05-07 |
| EP0813414A4 (en) | 1999-07-21 |
| LV11432A (en) | 1996-08-20 |
| BR9407869A (en) | 1996-10-29 |
| CZ109196A3 (en) | 1996-10-16 |
| JPH09504525A (en) | 1997-05-06 |
| KR960705575A (en) | 1996-11-08 |
| HUT75224A (en) | 1997-04-28 |
| CN1136278A (en) | 1996-11-20 |
| NO961536D0 (en) | 1996-04-18 |
| NO961536L (en) | 1996-06-18 |
| LV11432B (en) | 1996-12-20 |
| FI961681A0 (en) | 1996-04-17 |
| HU9601013D0 (en) | 1996-06-28 |
| AU8083694A (en) | 1995-05-08 |
| CA2173333A1 (en) | 1995-04-27 |
| EP0813414A1 (en) | 1997-12-29 |
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