IT1296495B1 - USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION - Google Patents

USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION

Info

Publication number
IT1296495B1
IT1296495B1 ITMI972603A IT1296495B1 IT 1296495 B1 IT1296495 B1 IT 1296495B1 IT MI972603 A ITMI972603 A IT MI972603A IT 1296495 B1 IT1296495 B1 IT 1296495B1
Authority
IT
Italy
Prior art keywords
bisphosphonates
preparation
intramuscular administration
pharmaceutical forms
pharmaceutical
Prior art date
Application number
Other languages
Italian (it)
Inventor
Tiberio Bruzzese
Angelo Bonabello
Giovanni Mozzi
Original Assignee
Prodotti Antibiotici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodotti Antibiotici Spa filed Critical Prodotti Antibiotici Spa
Priority to IT002603 priority Critical patent/IT1296495B1/en
Priority to ES9802412A priority patent/ES2152865B1/en
Priority to DE1998153483 priority patent/DE19853483A1/en
Priority to GB9825409A priority patent/GB2331459A/en
Priority to FR9814554A priority patent/FR2771638B1/en
Priority to BE9800841A priority patent/BE1012137A3/en
Publication of ITMI972603A1 publication Critical patent/ITMI972603A1/en
Application granted granted Critical
Publication of IT1296495B1 publication Critical patent/IT1296495B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT002603 1997-11-21 1997-11-21 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION IT1296495B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT002603 IT1296495B1 (en) 1997-11-21 1997-11-21 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION
ES9802412A ES2152865B1 (en) 1997-11-21 1998-11-17 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR INTRAMUSCULAR USE.
DE1998153483 DE19853483A1 (en) 1997-11-21 1998-11-19 Use of bisphosphonates for the production of pharmaceutical dosage forms for intramuscular use
GB9825409A GB2331459A (en) 1997-11-21 1998-11-19 Use of bisphosphonates in pharmaceutical preparations intended for intramuscular use
FR9814554A FR2771638B1 (en) 1997-11-21 1998-11-19 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS INTRA-MUSCULAR
BE9800841A BE1012137A3 (en) 1997-11-21 1998-11-20 Bisphosphonates use in the preparation of dosage forms intended use a intramuscular.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002603 IT1296495B1 (en) 1997-11-21 1997-11-21 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION

Publications (2)

Publication Number Publication Date
ITMI972603A1 ITMI972603A1 (en) 1999-05-21
IT1296495B1 true IT1296495B1 (en) 1999-06-25

Family

ID=11378254

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002603 IT1296495B1 (en) 1997-11-21 1997-11-21 USE OF BISPHOSPHONATES IN THE PREPARATION OF PHARMACEUTICAL FORMS FOR INTRAMUSCULAR ADMINISTRATION

Country Status (6)

Country Link
BE (1) BE1012137A3 (en)
DE (1) DE19853483A1 (en)
ES (1) ES2152865B1 (en)
FR (1) FR2771638B1 (en)
GB (1) GB2331459A (en)
IT (1) IT1296495B1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1136069A1 (en) * 2000-03-21 2001-09-26 SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. Pharmaceutical compositions containing clodronates for high local tolerance intramuscular administration
US8052987B2 (en) * 2000-06-20 2011-11-08 Novartis Pharmaceuticals Corporation Method of administering bisphosphonates
EP1591122B1 (en) * 2000-06-20 2012-09-26 Novartis AG Method of administering bisphosphonates
US6548042B2 (en) 2000-08-07 2003-04-15 Arstad Erik Bis-phosphonate compounds
ITTO20020406A1 (en) * 2002-05-13 2003-11-13 Chiesi Farma Spa FORMULATIONS OF BISPHOSPHONATES FOR INJECTABLE USE.
EP1605900A4 (en) * 2003-03-26 2007-10-17 Becton Dickinson Co Use of benzyl alcohol, and other phenolic preservatives to reduce pain during intradermal injection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0051163A3 (en) * 1980-11-03 1983-02-16 Dr. Franz Köhler Chemie KG A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation
JPS5862652A (en) * 1981-10-08 1983-04-14 Konishiroku Photo Ind Co Ltd Formation of direct positive color image
JPH03190823A (en) * 1989-12-21 1991-08-20 Snow Brand Milk Prod Co Ltd Erythropoietin hypodermic or intramuscular administration agent
CA2035179C (en) * 1990-01-31 2001-08-14 Gerald S. Brenner Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
BR9407869A (en) * 1993-10-19 1996-10-29 Merck & Co Inc Combination of pharmaceutical composition and process for the treatment of osteoporosis
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices

Also Published As

Publication number Publication date
GB2331459A (en) 1999-05-26
ITMI972603A1 (en) 1999-05-21
FR2771638A1 (en) 1999-06-04
BE1012137A3 (en) 2000-05-02
ES2152865B1 (en) 2001-08-16
GB9825409D0 (en) 1999-01-13
GB2331459A8 (en) 1999-07-15
DE19853483A1 (en) 1999-05-27
ES2152865A1 (en) 2001-02-01
FR2771638B1 (en) 2000-09-08

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Legal Events

Date Code Title Description
0001 Granted