FI955916A0 - N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2-bentsotiatsololeja luokan III rytmihäiriölääkkeinä - Google Patents

N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2-bentsotiatsololeja luokan III rytmihäiriölääkkeinä

Info

Publication number
FI955916A0
FI955916A0 FI955916A FI955916A FI955916A0 FI 955916 A0 FI955916 A0 FI 955916A0 FI 955916 A FI955916 A FI 955916A FI 955916 A FI955916 A FI 955916A FI 955916 A0 FI955916 A0 FI 955916A0
Authority
FI
Finland
Prior art keywords
pct
fluorophenoxy
piperidinyl
methylamino
butyl
Prior art date
Application number
FI955916A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI955916A7 (fi
FI955916L (fi
Inventor
Josef Jan Pieter Heykants
Marcel Jan Maria Borgers
Doris Wilgelm
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI955916A0 publication Critical patent/FI955916A0/fi
Publication of FI955916A7 publication Critical patent/FI955916A7/fi
Publication of FI955916L publication Critical patent/FI955916L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
FI955916A 1993-06-11 1994-06-06 N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2-bentsotiatsololeja luokan III rytmihäiriölääkkeinä FI955916L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201685 1993-06-11
PCT/EP1994/001849 WO1994029305A1 (en) 1993-06-11 1994-06-06 N-[[1-[4-(4-fluorophenoxy)butyl]-4-piperidinyl]-n-methylamino]-2-benzothiazolols as class iii antiarrhythmic agents

Publications (3)

Publication Number Publication Date
FI955916A0 true FI955916A0 (fi) 1995-12-08
FI955916A7 FI955916A7 (fi) 1995-12-08
FI955916L FI955916L (fi) 1995-12-08

Family

ID=8213890

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955916A FI955916L (fi) 1993-06-11 1994-06-06 N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2-bentsotiatsololeja luokan III rytmihäiriölääkkeinä

Country Status (34)

Country Link
US (1) US5691354A (cs)
EP (1) EP0701556B1 (cs)
JP (1) JP3498145B2 (cs)
KR (1) KR100337984B1 (cs)
CN (1) CN1039120C (cs)
AT (1) ATE159254T1 (cs)
AU (1) AU678841B2 (cs)
BG (1) BG62968B1 (cs)
BR (1) BR9406765A (cs)
CA (1) CA2163018A1 (cs)
CZ (1) CZ285766B6 (cs)
DE (1) DE69406284T2 (cs)
DK (1) DK0701556T3 (cs)
ES (1) ES2108471T3 (cs)
FI (1) FI955916L (cs)
GR (1) GR3025805T3 (cs)
HU (1) HU221620B1 (cs)
IL (1) IL109975A (cs)
LV (1) LV11544B (cs)
MY (1) MY111222A (cs)
NO (1) NO305123B1 (cs)
NZ (1) NZ268575A (cs)
OA (1) OA10201A (cs)
PH (1) PH31126A (cs)
PL (1) PL176775B1 (cs)
RO (1) RO115523B1 (cs)
RU (1) RU2122546C1 (cs)
SG (1) SG48821A1 (cs)
SI (1) SI9420036A (cs)
SK (1) SK281175B6 (cs)
TW (1) TW282469B (cs)
UA (1) UA41936C2 (cs)
WO (1) WO1994029305A1 (cs)
ZA (1) ZA944106B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA53649C2 (uk) * 1996-06-27 2003-02-17 Янссен Фармацевтика Н.В. N-[4-(гетероарилметил)феніл]гетероариламіни, композиція на їх основі та спосіб її одержання, спосіб одержання сполук (варіанти)
HUP0204496A3 (en) 2000-01-20 2004-07-28 Eisai Co Ltd Novel piperidine compounds and pharmaceutical compositions containing the same and process for preparation the same
RU2246895C2 (ru) * 2002-11-05 2005-02-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования желудочковых аритмий у кардиохирургических больных
RU2242254C2 (ru) * 2002-11-05 2004-12-20 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина Способ диагностики аритмий сердца
RU2261121C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения степени зависимости от электрокардиостимулятора
RU2261123C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования атриовентрикулярных блокад после радикальной кардиохирургической коррекции пороков сердца у детей раннего возраста
RU2261122C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения уровня атриовентрикулярной блокады у больных после хирургической коррекции пороков сердца
RU2261041C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования пароксизмальной эктопической атриовентрикулярной тахикардии
RU2261124C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ оценки электрических свойств рабочего миокарда

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA85187B (en) * 1984-01-09 1986-08-27 Janssen Pharmaceutica Nv 4-((bicyclic heterocyclyl)-methyl and-hetero)-piperidines
US5010198A (en) * 1984-12-03 1991-04-23 Janssen Pharmaceutica N.V. Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
CA2163018A1 (en) 1994-12-22
GR3025805T3 (en) 1998-03-31
OA10201A (en) 1996-12-18
TW282469B (cs) 1996-08-01
DE69406284T2 (de) 1998-02-19
FI955916A7 (fi) 1995-12-08
IL109975A0 (en) 1994-10-07
BG100210A (bg) 1996-07-31
SI9420036A (en) 1996-10-31
AU678841B2 (en) 1997-06-12
LV11544A (lv) 1996-10-20
ES2108471T3 (es) 1997-12-16
CZ285766B6 (cs) 1999-11-17
RU2122546C1 (ru) 1998-11-27
EP0701556B1 (en) 1997-10-15
BG62968B1 (bg) 2000-12-29
LV11544B (en) 1997-08-20
ZA944106B (en) 1995-12-11
PL311965A1 (en) 1996-03-18
PH31126A (en) 1998-02-23
KR100337984B1 (ko) 2002-10-25
CN1039120C (zh) 1998-07-15
HU221620B1 (hu) 2002-12-28
WO1994029305A1 (en) 1994-12-22
NZ268575A (en) 1996-08-27
HU9501971D0 (en) 1995-09-28
CZ319295A3 (en) 1996-03-13
EP0701556A1 (en) 1996-03-20
JP3498145B2 (ja) 2004-02-16
US5691354A (en) 1997-11-25
SG48821A1 (en) 1998-05-18
NO954801L (no) 1995-11-27
JPH08511014A (ja) 1996-11-19
CN1125443A (zh) 1996-06-26
SK281175B6 (sk) 2000-12-11
ATE159254T1 (de) 1997-11-15
NO954801D0 (no) 1995-11-27
SK154495A3 (en) 1996-06-05
MY111222A (en) 1999-09-30
PL176775B1 (pl) 1999-07-30
BR9406765A (pt) 1996-02-21
NO305123B1 (no) 1999-04-06
FI955916L (fi) 1995-12-08
DK0701556T3 (da) 1998-01-26
RO115523B1 (ro) 2000-03-30
AU7183894A (en) 1995-01-03
IL109975A (en) 1999-04-11
HUT73679A (en) 1996-09-30
UA41936C2 (uk) 2001-10-15
DE69406284D1 (de) 1997-11-20

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Legal Events

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MA Patent expired