FI940191A - New derivatives which are taxol analogues, their preparation and compositions containing them - Google Patents

New derivatives which are taxol analogues, their preparation and compositions containing them Download PDF

Info

Publication number
FI940191A
FI940191A FI940191A FI940191A FI940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A
Authority
FI
Finland
Prior art keywords
preparation
compositions containing
new derivatives
taxol analogues
taxol
Prior art date
Application number
FI940191A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI940191A0 (en
Inventor
Jean-Dominique Bourzat
Alain Commercon
Daniel Guenard
Francoise Gueritte-Voegelein
Pierre Potier
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI940191A publication Critical patent/FI940191A/en
Publication of FI940191A0 publication Critical patent/FI940191A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI940191A 1991-07-16 1994-01-14 New derivatives, which are taxol analogs, preparation of them and these containing compositions FI940191A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108937A FR2679230B1 (en) 1991-07-16 1991-07-16 NOVEL DERIVATIVES OF TAXOL ANALOGS, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
PCT/FR1992/000687 WO1993002065A1 (en) 1991-07-16 1992-07-16 New derivatives of taxol analogues, preparation thereof and compositions containing them

Publications (2)

Publication Number Publication Date
FI940191A true FI940191A (en) 1994-01-14
FI940191A0 FI940191A0 (en) 1994-01-14

Family

ID=9415141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940191A FI940191A0 (en) 1991-07-16 1994-01-14 New derivatives, which are taxol analogs, preparation of them and these containing compositions

Country Status (17)

Country Link
EP (2) EP0596010A1 (en)
JP (1) JPH06509107A (en)
AU (1) AU2388092A (en)
CA (1) CA2113074A1 (en)
CZ (1) CZ9094A3 (en)
FI (1) FI940191A0 (en)
FR (1) FR2679230B1 (en)
HU (1) HUT66600A (en)
IE (1) IE922305A1 (en)
MX (1) MX9204140A (en)
NO (1) NO934723D0 (en)
NZ (1) NZ243548A (en)
SK (1) SK4894A3 (en)
TW (1) TW201740B (en)
WO (1) WO1993002065A1 (en)
YU (1) YU69892A (en)
ZA (1) ZA925245B (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728725A (en) * 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5721268A (en) * 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6028205A (en) * 1991-09-23 2000-02-22 Florida State University C2 tricyclic taxanes
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US6005138A (en) * 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US6011056A (en) 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US5654447A (en) * 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5614549A (en) * 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
US5646176A (en) 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
DE69432140T2 (en) * 1993-03-05 2003-07-31 Univ Florida State Process for the preparation of 9-deoxotaxanes
US5547981A (en) * 1993-03-09 1996-08-20 Enzon, Inc. Taxol-7-carbazates
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
ATE249448T1 (en) * 1993-06-11 2003-09-15 Upjohn Co DELTA 6,7-TAXOL DERIVATIVES ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
CA2129288C (en) * 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives
FR2711370B1 (en) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa New taxoids, their preparation and the pharmaceutical compositions containing them.
US5880131A (en) * 1993-10-20 1999-03-09 Enzon, Inc. High molecular weight polymer-based prodrugs
EP0727992A4 (en) * 1993-10-20 2001-01-31 Enzon Inc 2'- and/or 7- substituted taxoids
US5965566A (en) * 1993-10-20 1999-10-12 Enzon, Inc. High molecular weight polymer-based prodrugs
IL127597A (en) * 1994-01-28 2003-07-31 Upjohn Co Iso-taxol analogs
WO1997042181A1 (en) 1996-05-06 1997-11-13 Florida State University 1-deoxy baccatin iii, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof
EP0930309A4 (en) * 1996-07-15 2001-09-26 Yakult Honsha Kk Taxane derivatives and drugs containing the same
GB9705903D0 (en) 1997-03-21 1997-05-07 Elliott Gillian D VP22 Proteins and uses thereof
WO1999032473A1 (en) * 1997-12-19 1999-07-01 Kabushiki Kaisha Yakult Honsha Taxane derivatives
CO5280224A1 (en) 2000-02-02 2003-05-30 Univ Florida State Res Found SUBSTITUTED TAXANS WITH ESTER IN C7, USEFUL AS ANTITUMOR AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE60133600T2 (en) 2000-02-02 2009-06-10 Florida State University Research Foundation, Inc., Tallahassee C7-CARBAMOYLOXY-SUBSTITUTED TAXANESE AS ANTITUM-MEANS
IL145640A (en) 2000-02-02 2007-02-11 Univ Florida State Res Found C10 carbamoyloxy substituted taxanes as antitumor agents
HUP0600533A2 (en) 2001-11-30 2006-11-28 Bristol Myers Squibb Co Paclitaxel solvates
WO2005035003A2 (en) * 2003-09-22 2005-04-21 Dihedron Corporation Compositions and methods for increasing drug efficiency
JP2007527432A (en) 2004-03-05 2007-09-27 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C7 lactyloxy-substituted taxane
CN104650012A (en) * 2013-11-22 2015-05-27 天士力控股集团有限公司 Taxane compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
NO934723L (en) 1993-12-20
SK4894A3 (en) 1994-12-07
JPH06509107A (en) 1994-10-13
NZ243548A (en) 1994-07-26
HU9400113D0 (en) 1994-05-30
CA2113074A1 (en) 1993-02-04
WO1993002065A1 (en) 1993-02-04
ZA925245B (en) 1993-04-28
EP0524093A1 (en) 1993-01-20
CZ9094A3 (en) 1994-06-15
FR2679230B1 (en) 1993-11-19
FI940191A0 (en) 1994-01-14
FR2679230A1 (en) 1993-01-22
MX9204140A (en) 1993-01-01
NO934723D0 (en) 1993-12-20
AU2388092A (en) 1993-02-23
IE922305A1 (en) 1993-01-27
YU69892A (en) 1995-10-03
TW201740B (en) 1993-03-11
HUT66600A (en) 1994-12-28
EP0596010A1 (en) 1994-05-11

Similar Documents

Publication Publication Date Title
FI940191A (en) New derivatives which are taxol analogues, their preparation and compositions containing them
FI925615A0 (en) PHARMACEUTICAL COMPOSITION OF THE STABILIZER, SOM INNEHAOLLER EN HMG-COA-REDUKTAS-INHIBITORFOERENING
FI981777A0 (en) Pharmaceutical composition
FI943571A (en) 1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives, their preparation and pharmaceutical compositions containing them
IL101882A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
FI951789A0 (en) Novel taxane derivatives, their preparation and pharmaceutical compositions containing them
IT8820386A0 (en) OROSOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING ACETYLCISTEINE.
IL101351A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
MX9200622A (en) PHARMACEUTICAL COMPOSITION
ZA93821B (en) New derivatives of baccatin III and of 10-deacetyibaccatin III, their preparation and the pharmaceutical compositions which contain them.
IL101888A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
FI945439A0 (en) Novel taxane derivatives, their preparation and compositions containing them
IT1290797B1 (en) STABILIZED PHARMACEUTICAL COMPOSITIONS
ITMI912261A0 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING CLOZAPINE, THEIR PREPARATION AND THEIR USE
KR900012897A (en) Guanidine derivatives and pharmaceutical compositions containing them
ITMI910846A1 (en) FLAVONI DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
MX9203732A (en) R-ENENOMERS OF N-PROPARGIL-1-AMINOINDAN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FI942675A0 (en) Novel substituted oxazinoisoquinoline derivatives, pharmaceutical compositions containing them and process for their preparation
IL101881A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IT1216120B (en) N_CYCLOALKYLAMINOETHYLBENZAMIDE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
ITFI920134A1 (en) 7-NEOPENTYL XANTINIC DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
NZ241309A (en) Heterocyclic amido prostaglandin analogues, preparation and pharmaceutical compositions thereof
ZA926829B (en) Novel substituted taxanes and pharmaceutical compositions containing them.
FI883793A0 (en) NY PHARMACEUTICAL COMPOSITION I FORM AV GRANULER OCH FOERFARANDE FOER FRAMSTAELLNING AV GRANULER.
ITMI912465A1 (en) DIIDAETIC IMIDAZOTIADIAZOLICI DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

Legal Events

Date Code Title Description
FD Application lapsed