FI934857A - Foerriktning av bindningspar in vivo - Google Patents

Foerriktning av bindningspar in vivo Download PDF

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Publication number
FI934857A
FI934857A FI934857A FI934857A FI934857A FI 934857 A FI934857 A FI 934857A FI 934857 A FI934857 A FI 934857A FI 934857 A FI934857 A FI 934857A FI 934857 A FI934857 A FI 934857A
Authority
FI
Finland
Prior art keywords
vindows
vivo
inspection
Prior art date
Application number
FI934857A
Other languages
English (en)
Other versions
FI934857A0 (fi
Inventor
Nicholas Pomato
Richard P Mccabe
Gregory Alan Hawkins
Reinhard Bredehorst
Chong-Ho Kim
Carl-Wilhelm Ernst Vogel
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI934857A0 publication Critical patent/FI934857A0/fi
Publication of FI934857A publication Critical patent/FI934857A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI934857A 1992-03-04 1993-11-03 Foerriktning av bindningspar in vivo FI934857A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84645392A 1992-03-04 1992-03-04
PCT/US1993/001858 WO1993017707A1 (en) 1992-03-04 1993-03-03 In vivo binding pair pretargeting

Publications (2)

Publication Number Publication Date
FI934857A0 FI934857A0 (fi) 1993-11-03
FI934857A true FI934857A (fi) 1993-12-03

Family

ID=25297986

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934857A FI934857A (fi) 1992-03-04 1993-11-03 Foerriktning av bindningspar in vivo

Country Status (7)

Country Link
US (2) US5578289A (fi)
EP (1) EP0590109A4 (fi)
JP (1) JPH06507918A (fi)
AU (1) AU663582B2 (fi)
CA (1) CA2107558A1 (fi)
FI (1) FI934857A (fi)
WO (1) WO1993017707A1 (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688488A (en) * 1989-04-03 1997-11-18 Purdue Research Foundation Composition and method for tumor imaging
WO1996000087A2 (en) * 1994-06-24 1996-01-04 Akzo Nobel N.V. Kit for pretargeting and novel pretargeting conjugates
JP2001512480A (ja) * 1997-02-19 2001-08-21 セントコア，インコーポレイテッド 持続的薬物送達およびそれに有用な組成物
WO1999036105A2 (en) * 1998-01-16 1999-07-22 Mca Development B.V. USE OF RADIOLABELED MONOCLONAL IgM IN THERAPY FOR CANCER AND AUTOIMMUNE DISEASE
CA2448995A1 (en) * 2003-11-12 2005-05-12 James Keenan Device and method for attracting diseased cells and foreign substances
US20070009427A1 (en) * 2005-07-06 2007-01-11 Syud Faisal A Compounds and methods for enhanced delivery to disease targets
US20070009428A1 (en) * 2005-07-06 2007-01-11 Syud Faisal A Compounds and methods for enhanced delivery to disease targets
US9557635B2 (en) * 2007-10-18 2017-01-31 Gearbox, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8227204B2 (en) * 2007-10-18 2012-07-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8684898B2 (en) * 2007-10-18 2014-04-01 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US8164074B2 (en) * 2007-10-18 2012-04-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8529426B2 (en) 2007-10-18 2013-09-10 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US8168958B2 (en) * 2007-10-18 2012-05-01 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US20090104113A1 (en) * 2007-10-18 2009-04-23 Searete Llc Ionizing-radiation-responsive compositions, methods, and systems
GB2453860B (en) 2007-10-18 2011-03-16 Searete Llc Ionizing-radiation-responsive compositions,methods and systems
JP2011504485A (ja) 2007-11-21 2011-02-10 ファーマクシス リミテッド Ｓｓａｏ／ｖａｐ−１のハロアリルアミン阻害剤およびその用途
US11054430B2 (en) 2015-07-08 2021-07-06 Defined Diagnostics, Llc Compounds and methods for the detection of methotrexate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002532A (en) * 1974-10-21 1977-01-11 Weltman Joel K Enzyme conjugates
GB1595101A (en) * 1977-03-15 1981-08-05 Hoffmann La Roche Enzyme modifier immunoassay
US4468469A (en) * 1981-11-04 1984-08-28 Miles Laboratories, Inc. Substituted phenylacetic acids and salts as TBP blocking agents in iodothyronine immunoassays
FR2523445A1 (fr) * 1982-03-17 1983-09-23 Sanofi Sa Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues
US4661347A (en) * 1982-11-12 1987-04-28 Scripps Clinic Cytotoxic compositions
US4975278A (en) * 1988-02-26 1990-12-04 Bristol-Myers Company Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
AU633867B2 (en) * 1989-02-02 1993-02-11 Eli Lilly And Company Delivery of cytotoxic agents
ATE177321T1 (de) * 1989-12-11 1999-03-15 Immunomedics Inc Verfahren zum aufspüren von diagnostischen oder therapeutischen mitteln durch antikörper
CA2005162A1 (en) * 1989-12-11 1991-06-11 Hans J. Hansen Method for antibody targeting of diagnostic or therapeutic agents

Also Published As

Publication number Publication date
JPH06507918A (ja) 1994-09-08
EP0590109A4 (en) 1995-04-19
US5578289A (en) 1996-11-26
WO1993017707A1 (en) 1993-09-16
US5807534A (en) 1998-09-15
CA2107558A1 (en) 1993-09-05
EP0590109A1 (en) 1994-04-06
FI934857A0 (fi) 1993-11-03
AU663582B2 (en) 1995-10-12
AU3736893A (en) 1993-10-05

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