FI933508A - Bicyklopolyazamakrocyklokarboxylsyrakomplex, konjugat daerav, foerfarande foer deras framstaellning och anvaendning som radiofarmaceutiska medel - Google Patents

Bicyklopolyazamakrocyklokarboxylsyrakomplex, konjugat daerav, foerfarande foer deras framstaellning och anvaendning som radiofarmaceutiska medel Download PDF

Info

Publication number
FI933508A
FI933508A FI933508A FI933508A FI933508A FI 933508 A FI933508 A FI 933508A FI 933508 A FI933508 A FI 933508A FI 933508 A FI933508 A FI 933508A FI 933508 A FI933508 A FI 933508A
Authority
FI
Finland
Prior art keywords
radiopharmaceutical
compound
macrocyclocarboxylic
bicyclopolyazam
acid complex
Prior art date
Application number
FI933508A
Other languages
English (en)
Finnish (fi)
Other versions
FI933508A0 (fi
Inventor
Garry E Kiefer
Jaime Simon
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of FI933508A0 publication Critical patent/FI933508A0/fi
Publication of FI933508A publication Critical patent/FI933508A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI933508A 1991-12-10 1993-08-09 Bicyklopolyazamakrocyklokarboxylsyrakomplex, konjugat daerav, foerfarande foer deras framstaellning och anvaendning som radiofarmaceutiska medel FI933508A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80539291A 1991-12-10 1991-12-10
PCT/US1992/010663 WO1993012112A1 (fr) 1991-12-10 1992-12-10 Complexes d'acides bicyclopolyazamacrocyclocarboxyliques, leurs conjugues, leurs procedes de preparation et leurs utilisations comme agents radiopharmaceutiques

Publications (2)

Publication Number Publication Date
FI933508A0 FI933508A0 (fi) 1993-08-09
FI933508A true FI933508A (fi) 1993-08-31

Family

ID=25191443

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933508A FI933508A (fi) 1991-12-10 1993-08-09 Bicyklopolyazamakrocyklokarboxylsyrakomplex, konjugat daerav, foerfarande foer deras framstaellning och anvaendning som radiofarmaceutiska medel

Country Status (10)

Country Link
EP (1) EP0575583A4 (fr)
KR (1) KR930703331A (fr)
AU (1) AU3275293A (fr)
CA (1) CA2103553A1 (fr)
FI (1) FI933508A (fr)
HU (1) HU9302308D0 (fr)
IL (1) IL104062A0 (fr)
MX (1) MX9207165A (fr)
WO (1) WO1993012112A1 (fr)
ZA (1) ZA929578B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5385893A (en) * 1993-05-06 1995-01-31 The Dow Chemical Company Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
CA2721093A1 (fr) 2008-04-11 2009-10-15 Merrimack Pharmaceuticals, Inc. Lieurs d'albumine de serum humain, et ses conjugues
RU2505499C1 (ru) * 2012-10-08 2014-01-27 Юлия Алексеевна Щепочкина Сырьевая смесь для имитации природного камня

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8502573D0 (sv) * 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
DE3825040A1 (de) * 1988-07-20 1990-01-25 Schering Ag 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US4940796A (en) * 1989-03-17 1990-07-10 The University Of Southern Mississippi 2,6-substituted-4-aminopyridines and their corresponding intermediates
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant

Also Published As

Publication number Publication date
AU3275293A (en) 1993-07-19
KR930703331A (ko) 1993-11-29
IL104062A0 (en) 1993-05-13
ZA929578B (en) 1994-06-10
WO1993012112A1 (fr) 1993-06-24
HU9302308D0 (en) 1993-12-28
EP0575583A4 (fr) 1995-02-15
FI933508A0 (fi) 1993-08-09
CA2103553A1 (fr) 1993-06-11
EP0575583A1 (fr) 1993-12-29
MX9207165A (es) 1993-06-01

Similar Documents

Publication Publication Date Title
FI833748A (fi) Immunogent protein- eller peptidkomplex, saett foer framstaellning och anvaendning daerav som immunstimulerande medel och saosom vaccin
FI935309A0 (fi) Vattenloesliga manganpartiklar som medel foer foerstaerkande av magnetisk resonanskontrast
FI872299A0 (fi) Heterocykliska analoger av mevalonolaktoner och deras derivat, foerfaranden foer deras framstaellning och deras anvaendning som farmaceutiska medel.
FI862256A (fi) Grundmjukgoerare som innehaoller katjoniskt ytaktivt medel och organisk syra.
FI945662A0 (fi) Roerformad stomme, i synnerhet som hylselement och med hylselement foersedd stomme
FI861532A0 (fi) Foerfarande foer att insamla uppgifter som en brand, branddetektor som utnyttjar detta foerfarande och brandalarmsystem som likasao utnyttjar detta foerfarande.
DE68903192D1 (de) Orale praeparate.
FI923558A (fi) Tetrahydroindazol-, tetrahydrocyklopentapyrazol- och hexahydrocykloheptapyrazolfoereningar och deras anvaendning som inhibitorer av hmg-coa-reduktas
FI923185A0 (fi) Foerfarande och anordning foer framstaellning av fogloesa band- och traodoeglor och deras anvaendning som kapverktyg i band- och traodsaogar.
FI932625A0 (fi) Anordning och foerfarande foer detektering av ytfel i laonga, i roerelse befintliga metallprodukter
FI911863A0 (fi) Metylendifosfonsyra och antiinflammatoriskt medel innehaollande denna foerening som aktivkomponent.
FI912931A0 (fi) Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel.
FI891227A (fi) Katekolderivat och farmaceutiska preparat som innehaoller dessa.
FI880437A (fi) Fukt- och gastaet foerpackning och maskin foer framstaellning, fyllning och foerslutning av en dylik foerpackning.
FI922472A0 (fi) Gingerol- och gingerdiolderivat som hypokolesterolemiska och antiaterosklerostiska medel.
FI933508A (fi) Bicyklopolyazamakrocyklokarboxylsyrakomplex, konjugat daerav, foerfarande foer deras framstaellning och anvaendning som radiofarmaceutiska medel
FI883315A0 (fi) 1h-pyrazol-1-alkanamider anvaendbara som antiarrytmiska medel och deras framstaellning.
FI892207A0 (fi) 2-adamantyl-4-isotiazolin-3-oner, deras tillverkningsfoerfarande och anvaendning som baktericida och fungicida medel.
FI865028A (fi) Foerfarande foer framstaellning av heteroaromatiska acetylener anvaendbara som hypertensiva medel.
FI931159A0 (fi) Dosaerosoler, som innehaoller som aktivt aemne flezelastin och med dettarelaterade strukturer
FI821896A0 (fi) 4-amino-bentsylamin-derivater, foerfarande foer deras framstaellning och deras anvaendning som farmaceutiska medel
FI905949A (fi) Foerfarande och medel foer bestaemning av urea.
FI863056A0 (fi) Anvaendning av kopolyamider som i vaerme smaeltande lim och limningsfoerfarande.
FI912314A0 (fi) Utfaellningsmedel och flockuleringsmedel foer behandling av avfallsvatten och foerfarande, som anvaender dessa medel.
FI916175A0 (fi) Anvaendning av ett hydrofobt ytaktivt medel som tillsatsmedel i formslaeppmedel.

Legal Events

Date Code Title Description
FD Application lapsed