FI933477A - Monohydrat av ett dinatriumsalt av 4-klorfenyltiometylenbisfosfonsyra,dess framstaellning och farmaceutiska kompositioner innehaollande detta - Google Patents

Monohydrat av ett dinatriumsalt av 4-klorfenyltiometylenbisfosfonsyra,dess framstaellning och farmaceutiska kompositioner innehaollande detta Download PDF

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Publication number
FI933477A
FI933477A FI933477A FI933477A FI933477A FI 933477 A FI933477 A FI 933477A FI 933477 A FI933477 A FI 933477A FI 933477 A FI933477 A FI 933477A FI 933477 A FI933477 A FI 933477A
Authority
FI
Finland
Prior art keywords
chlorophenylthiomethylenebisphosphonium
monohydrates
preparation
pharmaceutical compositions
disodium salts
Prior art date
Application number
FI933477A
Other languages
English (en)
Other versions
FI933477A0 (fi
Inventor
Michel Bonnery
Michel Bouisset
Raphael Sole
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of FI933477A0 publication Critical patent/FI933477A0/fi
Publication of FI933477A publication Critical patent/FI933477A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3865—Polyphosphonic acids containing sulfur substituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI933477A 1992-08-05 1993-08-05 Monohydrat av ett dinatriumsalt av 4-klorfenyltiometylenbisfosfonsyra,dess framstaellning och farmaceutiska kompositioner innehaollande detta FI933477A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9209718A FR2694558B1 (fr) 1992-08-05 1992-08-05 Monohydrate du sel disodique de l'acide 4-chlorophénylthiométhylène bisphosphonique, sa préparation, les compositions pharmaceutiques en contenant.

Publications (2)

Publication Number Publication Date
FI933477A0 FI933477A0 (fi) 1993-08-05
FI933477A true FI933477A (fi) 1994-02-06

Family

ID=9432642

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933477A FI933477A (fi) 1992-08-05 1993-08-05 Monohydrat av ett dinatriumsalt av 4-klorfenyltiometylenbisfosfonsyra,dess framstaellning och farmaceutiska kompositioner innehaollande detta

Country Status (8)

Country Link
US (2) US5405994A (fi)
EP (1) EP0582515A1 (fi)
JP (1) JP2735462B2 (fi)
CA (1) CA2103655A1 (fi)
FI (1) FI933477A (fi)
FR (1) FR2694558B1 (fi)
HU (2) HUT64767A (fi)
MX (1) MX9304721A (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727629A1 (fr) * 1994-12-06 1996-06-07 Sanofi Sa Trousse pour cycle de traitement de l'osteoporose
US5656288A (en) * 1995-06-08 1997-08-12 Sanofi Winthrop, Inc. Stable pharmaceutical compositions containing tiludronate hydrates and process for producing the pharmaceutical compositions
PE20011065A1 (es) 2000-02-01 2001-11-21 Procter & Gamble Proceso para fabricar bisfosfonatos geminales
US6410520B2 (en) * 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
JP2002255876A (ja) * 2001-02-23 2002-09-11 Showa Denko Kk プロパルギルアルコールの精製方法および製造方法
TWI315982B (en) * 2001-07-19 2009-10-21 Novartis Ag Combinations comprising epothilones and pharmaceutical uses thereof
RU2326695C2 (ru) * 2003-09-19 2008-06-20 Пфайзер Продактс Инк. Фармацевтические композиции и способы, включающие комбинации 2-алкилиденовых производных 9-нор-витамина d и бисфосфоната
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
WO2006100527A1 (en) * 2005-03-24 2006-09-28 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Effervescent tablet containing sodium alendronate and related use and process
WO2016054056A1 (en) * 2014-10-01 2016-04-07 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Methods of treating pxe with tnap inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof

Also Published As

Publication number Publication date
FR2694558B1 (fr) 1994-10-28
EP0582515A1 (fr) 1994-02-09
FR2694558A1 (fr) 1994-02-11
HU9302257D0 (en) 1993-10-28
MX9304721A (es) 1994-05-31
US5405994A (en) 1995-04-11
FI933477A0 (fi) 1993-08-05
HU211565A9 (en) 1995-12-28
JP2735462B2 (ja) 1998-04-02
CA2103655A1 (en) 1994-02-06
US5739381A (en) 1998-04-14
HUT64767A (en) 1994-02-28
JPH06157565A (ja) 1994-06-03

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Owner name: SANOFI