FI930525A - Process for the preparation of 3- [2- (dimethylamino) ethyl] -N-methyl-1H-indole-5-methanesulfonamides - Google Patents

Process for the preparation of 3- [2- (dimethylamino) ethyl] -N-methyl-1H-indole-5-methanesulfonamides Download PDF

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Publication number
FI930525A
FI930525A FI930525A FI930525A FI930525A FI 930525 A FI930525 A FI 930525A FI 930525 A FI930525 A FI 930525A FI 930525 A FI930525 A FI 930525A FI 930525 A FI930525 A FI 930525A
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FI
Finland
Prior art keywords
indole
dimethylamino
ethyl
methyl
methanesulfonamides
Prior art date
Application number
FI930525A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI105021B (en
FI930525A0 (en
Inventor
Barjoan Pere Dalmases
Olondriz Francisco Marquillas
Rovira Ana Bosch
Ges Jose Maria Caldero
Original Assignee
Vita Invest Sa
Sint Quimica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Invest Sa, Sint Quimica Sa filed Critical Vita Invest Sa
Priority to FI930525A priority Critical patent/FI105021B/en
Publication of FI930525A0 publication Critical patent/FI930525A0/en
Publication of FI930525A publication Critical patent/FI930525A/en
Application granted granted Critical
Publication of FI105021B publication Critical patent/FI105021B/en

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  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a process wherein 2-carboxy-3-[2- (dimethylamino)ethyl]-N-methyl-1H-indole-5-methane sulphonamide (formula II) is decarboxylated in the presence of a suitable solvate and a suitable catalyst in an inert atmosphere and in the temperature of 189 degree C to 250 degree C, wherein 3-[2-(dimethylamino)ethyl]-N-methyl-1H- indole-5-methanesulphonamide (formula I) is produced, the salts and solvates thereof being useful in the management of migraines. <IMAGE> <IMAGE>
FI930525A 1993-02-08 1993-02-08 Process for the preparation of 3-[2-(dimethylamino)- ethyl]-N-methyl-1H-indole-5-methanesulphonamide FI105021B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI930525A FI105021B (en) 1993-02-08 1993-02-08 Process for the preparation of 3-[2-(dimethylamino)- ethyl]-N-methyl-1H-indole-5-methanesulphonamide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI930525A FI105021B (en) 1993-02-08 1993-02-08 Process for the preparation of 3-[2-(dimethylamino)- ethyl]-N-methyl-1H-indole-5-methanesulphonamide
FI930525 1993-02-08

Publications (3)

Publication Number Publication Date
FI930525A0 FI930525A0 (en) 1993-02-08
FI930525A true FI930525A (en) 1994-08-09
FI105021B FI105021B (en) 2000-05-31

Family

ID=8537218

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930525A FI105021B (en) 1993-02-08 1993-02-08 Process for the preparation of 3-[2-(dimethylamino)- ethyl]-N-methyl-1H-indole-5-methanesulphonamide

Country Status (1)

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FI (1) FI105021B (en)

Also Published As

Publication number Publication date
FI105021B (en) 2000-05-31
FI930525A0 (en) 1993-02-08

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