FI921091A - Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives - Google Patents

Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives Download PDF

Info

Publication number
FI921091A
FI921091A FI921091A FI921091A FI921091A FI 921091 A FI921091 A FI 921091A FI 921091 A FI921091 A FI 921091A FI 921091 A FI921091 A FI 921091A FI 921091 A FI921091 A FI 921091A
Authority
FI
Finland
Prior art keywords
quinoxaline
phenyl
preparation
therapeutically active
dione derivatives
Prior art date
Application number
FI921091A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI98370C (en
FI98370B (en
FI921091A0 (en
Inventor
Kenneth Shaw
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Priority to FI921091A priority Critical patent/FI98370C/en
Publication of FI921091A0 publication Critical patent/FI921091A0/en
Publication of FI921091A publication Critical patent/FI921091A/en
Application granted granted Critical
Publication of FI98370B publication Critical patent/FI98370B/en
Publication of FI98370C publication Critical patent/FI98370C/en

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a process for preparing an imidazo[1,5-a]quinoxaline-1,3-dione derivative of the formula I, <IMAGE> in which R1 and R4 denote hydrogen, alkyl or alkoxy, X is hydrogen, halogen, hydroxyl, amino or mono- or dialkylamino, W is an optionally substituted phenyl, thienyl or pyridyl group, and R2 and R3 denote hydrogen or various substituents as defined in the patent claims, and their pharmaceutically acceptable salts. These compounds are extremely selective brain GABAa receptor agonists, antagonists or invert agonists or their precursors and they can be used for diagnosing and treating anxiety, sleep disturbances and disease attacks, overdosing with drugs of the benzodiazepine type and for improving the memory.
FI921091A 1992-03-13 1992-03-13 Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives FI98370C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI921091A FI98370C (en) 1992-03-13 1992-03-13 Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI921091A FI98370C (en) 1992-03-13 1992-03-13 Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives
FI921091 1992-03-13

Publications (4)

Publication Number Publication Date
FI921091A0 FI921091A0 (en) 1992-03-13
FI921091A true FI921091A (en) 1993-09-14
FI98370B FI98370B (en) 1997-02-28
FI98370C FI98370C (en) 1997-06-10

Family

ID=8534919

Family Applications (1)

Application Number Title Priority Date Filing Date
FI921091A FI98370C (en) 1992-03-13 1992-03-13 Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives

Country Status (1)

Country Link
FI (1) FI98370C (en)

Also Published As

Publication number Publication date
FI98370C (en) 1997-06-10
FI98370B (en) 1997-02-28
FI921091A0 (en) 1992-03-13

Similar Documents

Publication Publication Date Title
MY107157A (en) Quinuclidine derivatives.
CA2175204A1 (en) Certain Fused Pyrrolecarboxanilides; a New Class of GABA Brain Receptor Ligands
NO153220C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMIDAZOLINE DERIVATIVES.
NO962386L (en) Heterocyclic ring-condensed pyrimidine derivatives
OA09579A (en) Certain imidazoquinoxalines a new class of gaba brain receptor ligands
PT819129E (en) PIRAZOLE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION
HUP9901820A2 (en) 4-amino pyrimidine derivatives, medicaments containing these compounds, their use and process for their production
CA2102179A1 (en) Quinuclidine derivatives
NZ510629A (en) [1,2,4]Triazolo[1,5-c]pyrimidine derivatives and pharmaceutical use as adenosine A2A receptor antagonists
CA2184802A1 (en) Process for manufacture of imidazo benzodiazepine derivatives
LV12539A (en) Substituted 4-oxo-napthyridine-3-carboxamides as gaba brain receptor ligands
AU685881B2 (en) 5-heteroarylindole derivatives as benzodiazepine receptor site agonists and antagonists
MXPA04003278A (en) 5-methoxy-8-aryl-[1,2,4] triazolo [1,5-a] pyridine derivatives as adenosine receptor antagonists.
FI921091A (en) Process for the preparation of therapeutically active 2-phenyl-substituted imidazo [1,5-a] quinoxaline-1,3 (2H, 5H) -dione derivatives
DE69413112T2 (en) 5-HT3 pyrrolopyrazine derivatives
US3957766A (en) Novel nitrofuran compounds and pharmaceutical compositions
EG15805A (en) Process for preparing of imidazo(1,2-a) quinoline derivatives
CA2223936A1 (en) Novel substituted aryl and cycloalkyl imidazolones; a new class of gaba brain receptor ligands
ATE5480T1 (en) THIAZOLO(3,2-A)PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE DERIVATIVES.
US3879392A (en) Pyrido(4,3-c)pyridazine compounds
US3849400A (en) 2-(substituted anilino)-4,5-dihydro-3h-1,3-benzodiazepines
NO177931C (en) Analogous Process for Preparation of Therapeutically Active Piperazine Derivatives
CA2042327A1 (en) Pyrrolo¬2,3-b|indole-ketones and analogs, a process for their preparation and their use as medicaments
CA2249562A1 (en) Certain fused pyrrolecarboxamides as gaba brain receptor ligands
FI921298A (en) Process for the preparation of a 5- (6-imidazo / 1,2-a / pyridyl) pyridine derivative useful as a drug

Legal Events

Date Code Title Description
BB Publication of examined application