FI910894A - Process for the preparation of therapeutically useful N-cycloalkylalkylamines - Google Patents
Process for the preparation of therapeutically useful N-cycloalkylalkylamines Download PDFInfo
- Publication number
- FI910894A FI910894A FI910894A FI910894A FI910894A FI 910894 A FI910894 A FI 910894A FI 910894 A FI910894 A FI 910894A FI 910894 A FI910894 A FI 910894A FI 910894 A FI910894 A FI 910894A
- Authority
- FI
- Finland
- Prior art keywords
- cycloalkylalkylamines
- preparation
- therapeutically useful
- lower alkyl
- thienyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
N-Cycloalkylalkylamines of general formula (I) <IMAGE> in which: R1 is a furyl or thienyl radical or is a phenyl radical, provided that Q denotes a 1,2-cyclopropanediyl group, R2 is lower alkyl, R3 is hydrogen or lower alkyl, m has the value 1 or 2, R4 is cycloalkyl -CH(CH2)n, in which n is an integer from 2 to 5, R5 is optionally substituted phenyl or thienyl, Q is 1,2-ethylenediyl or 1,2-cyclopropanediyl, and their addition salts with acids. These amines are psychotropic medications and are also useful in gastroenterology.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/484,403 US5034419A (en) | 1988-09-01 | 1990-02-26 | N-cycloalkylalkylamines, process for their preparation, their use as medicament and their synthesis intermediates |
US48440390 | 1990-02-26 | ||
FR9002494 | 1990-02-28 | ||
FR9002494A FR2658822A1 (en) | 1990-02-28 | 1990-02-28 | N-Cycloalkylalkylamines, process for their preparation, their use as medicaments and their synthetic intermediates |
Publications (4)
Publication Number | Publication Date |
---|---|
FI910894A0 FI910894A0 (en) | 1991-02-25 |
FI910894A true FI910894A (en) | 1991-08-27 |
FI97384B FI97384B (en) | 1996-08-30 |
FI97384C FI97384C (en) | 1996-12-10 |
Family
ID=26227891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI910894A FI97384C (en) | 1990-02-26 | 1991-02-25 | Process for the preparation of therapeutically useful N-cycloalkylalkylamines |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0445013B1 (en) |
JP (1) | JP2899429B2 (en) |
AT (1) | ATE106879T1 (en) |
AU (1) | AU633695B2 (en) |
CA (1) | CA2037114C (en) |
DE (1) | DE69102309T2 (en) |
DK (1) | DK0445013T3 (en) |
ES (1) | ES2054452T3 (en) |
FI (1) | FI97384C (en) |
HU (1) | HU215430B (en) |
IE (1) | IE66180B1 (en) |
IL (1) | IL97354A (en) |
NZ (1) | NZ237224A (en) |
PT (1) | PT96885B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2713639B1 (en) * | 1993-12-09 | 1996-08-30 | Irj | New derivatives of 2-arylalkenyl-azacycloalkanes ligands to sigma receptors, their preparation process and their use in therapy. |
GB9405392D0 (en) * | 1994-03-18 | 1994-05-04 | Secr Defence | Microorganism detection apparatus and method |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS584748A (en) * | 1981-06-30 | 1983-01-11 | Takasago Corp | Preparation of enamine or imine |
IL86740A (en) * | 1987-06-30 | 1992-11-15 | Tanabe Seiyaku Co | Thiphene derivatives,their preparation and pharmaceutical compositions containing them |
JPS6416778A (en) * | 1987-07-09 | 1989-01-20 | Tanabe Seiyaku Co | Thiophene derivative |
-
1991
- 1991-02-25 AT AT91400497T patent/ATE106879T1/en not_active IP Right Cessation
- 1991-02-25 DK DK91400497.3T patent/DK0445013T3/en active
- 1991-02-25 FI FI910894A patent/FI97384C/en active
- 1991-02-25 CA CA002037114A patent/CA2037114C/en not_active Expired - Fee Related
- 1991-02-25 IE IE62091A patent/IE66180B1/en not_active IP Right Cessation
- 1991-02-25 HU HU91625A patent/HU215430B/en not_active IP Right Cessation
- 1991-02-25 EP EP91400497A patent/EP0445013B1/en not_active Expired - Lifetime
- 1991-02-25 IL IL9735491A patent/IL97354A/en not_active IP Right Cessation
- 1991-02-25 DE DE69102309T patent/DE69102309T2/en not_active Expired - Fee Related
- 1991-02-25 ES ES91400497T patent/ES2054452T3/en not_active Expired - Lifetime
- 1991-02-25 AU AU71340/91A patent/AU633695B2/en not_active Ceased
- 1991-02-26 JP JP3031059A patent/JP2899429B2/en not_active Expired - Fee Related
- 1991-02-26 PT PT96885A patent/PT96885B/en not_active IP Right Cessation
- 1991-02-26 NZ NZ237224A patent/NZ237224A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE106879T1 (en) | 1994-06-15 |
FI97384B (en) | 1996-08-30 |
CA2037114A1 (en) | 1991-08-27 |
IL97354A (en) | 1995-12-08 |
HU215430B (en) | 1999-09-28 |
DE69102309D1 (en) | 1994-07-14 |
CA2037114C (en) | 2003-09-09 |
NZ237224A (en) | 1992-05-26 |
FI910894A0 (en) | 1991-02-25 |
EP0445013B1 (en) | 1994-06-08 |
DE69102309T2 (en) | 1994-09-15 |
HUT62284A (en) | 1993-04-28 |
IL97354A0 (en) | 1992-05-25 |
DK0445013T3 (en) | 1994-07-11 |
AU7134091A (en) | 1991-08-29 |
IE910620A1 (en) | 1991-08-28 |
AU633695B2 (en) | 1993-02-04 |
JPH0616598A (en) | 1994-01-25 |
EP0445013A1 (en) | 1991-09-04 |
IE66180B1 (en) | 1995-12-13 |
FI97384C (en) | 1996-12-10 |
JP2899429B2 (en) | 1999-06-02 |
HU910625D0 (en) | 1991-09-30 |
ES2054452T3 (en) | 1994-08-01 |
PT96885A (en) | 1991-10-31 |
PT96885B (en) | 1998-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application |