FI906113A0 - Antivirala foereningar. - Google Patents
Antivirala foereningar.Info
- Publication number
- FI906113A0 FI906113A0 FI906113A FI906113A FI906113A0 FI 906113 A0 FI906113 A0 FI 906113A0 FI 906113 A FI906113 A FI 906113A FI 906113 A FI906113 A FI 906113A FI 906113 A0 FI906113 A0 FI 906113A0
- Authority
- FI
- Finland
- Prior art keywords
- formula
- antiviral
- foereningar
- chem
- residue
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 239000002777 nucleoside Substances 0.000 abstract 2
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898908355A GB8908355D0 (en) | 1988-04-18 | 1989-04-13 | Output apparatus antiviral compounds |
| PCT/GB1990/000542 WO1990012023A1 (en) | 1989-04-13 | 1990-04-10 | Antiviral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI906113A0 true FI906113A0 (fi) | 1990-12-12 |
Family
ID=10654960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI906113A FI906113A0 (fi) | 1989-04-13 | 1990-12-12 | Antivirala foereningar. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0392791B1 (xx) |
| JP (1) | JPH03505880A (xx) |
| KR (1) | KR920700217A (xx) |
| CN (1) | CN1046531A (xx) |
| AT (1) | ATE125817T1 (xx) |
| AU (1) | AU5407890A (xx) |
| CA (1) | CA2028151A1 (xx) |
| DE (1) | DE69021242T2 (xx) |
| ES (1) | ES2077643T3 (xx) |
| FI (1) | FI906113A0 (xx) |
| GB (1) | GB2230266B (xx) |
| NZ (1) | NZ233197A (xx) |
| OA (1) | OA09553A (xx) |
| PT (1) | PT93743A (xx) |
| WO (1) | WO1990012023A1 (xx) |
| ZA (1) | ZA902784B (xx) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6903224B2 (en) | 1988-04-11 | 2005-06-07 | Biochem Pharma Inc. | Substituted 1,3-oxathiolanes |
| US7119202B1 (en) | 1989-02-08 | 2006-10-10 | Glaxo Wellcome Inc. | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties |
| US5270315A (en) * | 1988-04-11 | 1993-12-14 | Biochem Pharma Inc. | 4-(purinyl bases)-substituted-1,3-dioxlanes |
| US6350753B1 (en) | 1988-04-11 | 2002-02-26 | Biochem Pharma Inc. | 2-Substituted-4-substituted-1,3-dioxolanes and use thereof |
| UA45942A (uk) * | 1989-02-08 | 2002-05-15 | Біокем Фарма, Інк. | 1,3-оксатіолан, його похідні, спосіб (варіанти) його одержання та фармацевтична композиція |
| MY104575A (en) * | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
| US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| US6642245B1 (en) | 1990-02-01 | 2003-11-04 | Emory University | Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane |
| US5728575A (en) | 1990-02-01 | 1998-03-17 | Emory University | Method of resolution of 1,3-oxathiolane nucleoside enantiomers |
| US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
| US6703396B1 (en) | 1990-02-01 | 2004-03-09 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers |
| GB9009861D0 (en) | 1990-05-02 | 1990-06-27 | Glaxo Group Ltd | Chemical compounds |
| US6228860B1 (en) | 1990-11-13 | 2001-05-08 | Biochem Pharma Inc. | Substituted 1,3-oxathiolanes with antiviral properties |
| US6369066B1 (en) | 1990-11-13 | 2002-04-09 | Biochem Pharma, Inc. | Substituted 1,3-oxathiolanes with antiviral properties |
| US5587480A (en) * | 1990-11-13 | 1996-12-24 | Biochem Pharma, Inc. | Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties |
| US5444063A (en) * | 1990-12-05 | 1995-08-22 | Emory University | Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity |
| US5925643A (en) * | 1990-12-05 | 1999-07-20 | Emory University | Enantiomerically pure β-D-dioxolane-nucleosides |
| AU1254892A (en) * | 1990-12-18 | 1992-07-22 | Sloan-Kettering Institute For Cancer Research | Novel synthesis of 2'-"up" fluorinated 2''-deoxy-arabinofuranosylpurines |
| IL100502A (en) * | 1991-01-03 | 1995-12-08 | Iaf Biochem Int | PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (- |
| US6812233B1 (en) | 1991-03-06 | 2004-11-02 | Emory University | Therapeutic nucleosides |
| US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
| GB9110874D0 (en) * | 1991-05-20 | 1991-07-10 | Iaf Biochem Int | Medicaments |
| ZA923641B (en) * | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
| FR2685331A1 (fr) * | 1991-12-12 | 1993-06-25 | Centre Nat Rech Scient | Phosphotriesters de la ddu, leur preparation et leur application en therapeutique. |
| US5679652A (en) * | 1992-02-13 | 1997-10-21 | Schott; Herbert | Amphiphilic nucleosidephosphate analogues |
| US6444656B1 (en) | 1992-12-23 | 2002-09-03 | Biochem Pharma, Inc. | Antiviral phosphonate nucleotides |
| US6005107A (en) | 1992-12-23 | 1999-12-21 | Biochem Pharma, Inc. | Antiviral compounds |
| GB9226879D0 (en) * | 1992-12-23 | 1993-02-17 | Iaf Biochem Int | Anti-viral compounds |
| US20020120130A1 (en) | 1993-09-10 | 2002-08-29 | Gilles Gosselin | 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents |
| US5587362A (en) * | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
| HUT76331A (en) * | 1994-07-15 | 1997-08-28 | Lepetit Spa | Dinucleoside-5',5'-pyrophosphates |
| IL115156A (en) | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
| US5703058A (en) | 1995-01-27 | 1997-12-30 | Emory University | Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
| US6391859B1 (en) | 1995-01-27 | 2002-05-21 | Emory University | [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides |
| US5808040A (en) * | 1995-01-30 | 1998-09-15 | Yale University | L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides |
| AU722214B2 (en) | 1995-06-07 | 2000-07-27 | Centre National De La Recherche Scientifique (Cnrs) | Nucleosides with anti-hepatitis B virus activity |
| US5753789A (en) * | 1996-07-26 | 1998-05-19 | Yale University | Oligonucleotides containing L-nucleosides |
| WO2001012644A1 (en) * | 1999-08-17 | 2001-02-22 | Adani, Alexander | Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptases and viruses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA931561A (en) * | 1969-03-10 | 1973-08-07 | Syntex Corporation | Nucleoside phosphonates, phosphonic acids, phosphonic acid salts, and process for producing same |
| CA1330794C (en) * | 1987-03-27 | 1994-07-19 | Phillip Frost | Anti-viral compounds, dosage forms and methods |
-
1990
- 1990-04-04 NZ NZ233197A patent/NZ233197A/xx unknown
- 1990-04-10 DE DE69021242T patent/DE69021242T2/de not_active Expired - Fee Related
- 1990-04-10 AU AU54078/90A patent/AU5407890A/en not_active Abandoned
- 1990-04-10 JP JP2505653A patent/JPH03505880A/ja active Pending
- 1990-04-10 KR KR1019900702612A patent/KR920700217A/ko not_active Application Discontinuation
- 1990-04-10 AT AT90303818T patent/ATE125817T1/de not_active IP Right Cessation
- 1990-04-10 WO PCT/GB1990/000542 patent/WO1990012023A1/en active Application Filing
- 1990-04-10 GB GB9008105A patent/GB2230266B/en not_active Expired - Lifetime
- 1990-04-10 CA CA002028151A patent/CA2028151A1/en not_active Abandoned
- 1990-04-10 ES ES90303818T patent/ES2077643T3/es not_active Expired - Lifetime
- 1990-04-10 EP EP90303818A patent/EP0392791B1/en not_active Expired - Lifetime
- 1990-04-11 PT PT93743A patent/PT93743A/pt not_active Application Discontinuation
- 1990-04-11 ZA ZA902784A patent/ZA902784B/xx unknown
- 1990-04-13 CN CN90103632A patent/CN1046531A/zh active Pending
- 1990-11-15 OA OA59895A patent/OA09553A/en unknown
- 1990-12-12 FI FI906113A patent/FI906113A0/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03505880A (ja) | 1991-12-19 |
| KR920700217A (ko) | 1992-02-19 |
| CA2028151A1 (en) | 1990-10-14 |
| DE69021242D1 (de) | 1995-09-07 |
| ES2077643T3 (es) | 1995-12-01 |
| PT93743A (pt) | 1990-11-20 |
| CN1046531A (zh) | 1990-10-31 |
| GB2230266B (en) | 1992-08-12 |
| GB9008105D0 (en) | 1990-06-06 |
| WO1990012023A1 (en) | 1990-10-18 |
| NZ233197A (en) | 1991-11-26 |
| ZA902784B (en) | 1991-12-24 |
| GB2230266A (en) | 1990-10-17 |
| AU5407890A (en) | 1990-11-05 |
| EP0392791A1 (en) | 1990-10-17 |
| EP0392791B1 (en) | 1995-08-02 |
| DE69021242T2 (de) | 1996-01-11 |
| ATE125817T1 (de) | 1995-08-15 |
| OA09553A (en) | 1993-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed | ||
| MM | Patent lapsed |
Owner name: WALKER, RICHARD THOMAS Owner name: JONES, ALBERT STANLEY |