FI896238A0 - Renininhibitorer. - Google Patents

Renininhibitorer.

Info

Publication number
FI896238A0
FI896238A0 FI896238A FI896238A FI896238A0 FI 896238 A0 FI896238 A0 FI 896238A0 FI 896238 A FI896238 A FI 896238A FI 896238 A FI896238 A FI 896238A FI 896238 A0 FI896238 A0 FI 896238A0
Authority
FI
Finland
Prior art keywords
renininhibitorer
Prior art date
Application number
FI896238A
Other languages
English (en)
Finnish (fi)
Inventor
Jay Donald Albright
Fuk-Wah Sum
Charles Frederick Howell
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI896238A0 publication Critical patent/FI896238A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI896238A 1988-12-27 1989-12-22 Renininhibitorer. FI896238A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29007988A 1988-12-27 1988-12-27

Publications (1)

Publication Number Publication Date
FI896238A0 true FI896238A0 (fi) 1989-12-22

Family

ID=23114455

Family Applications (1)

Application Number Title Priority Date Filing Date
FI896238A FI896238A0 (fi) 1988-12-27 1989-12-22 Renininhibitorer.

Country Status (11)

Country Link
EP (1) EP0376012A3 (ja)
JP (1) JPH02215799A (ja)
KR (1) KR900009688A (ja)
AU (1) AU4721489A (ja)
CA (1) CA2006374A1 (ja)
DK (1) DK661789A (ja)
FI (1) FI896238A0 (ja)
IL (1) IL92643A0 (ja)
NO (1) NO895230L (ja)
PT (1) PT92732A (ja)
ZA (1) ZA899924B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427939A3 (en) * 1989-10-11 1991-11-06 American Cyanamid Company Renin inhibitors
JP2578044B2 (ja) * 1992-03-14 1997-02-05 呉羽化学工業株式会社 フェニルアラニン−グリシン誘導体、その製造方法、及びその誘導体を含有する抗腫瘍剤
US6159938A (en) * 1994-11-21 2000-12-12 Cortech, Inc. Serine protease inhibitors comprising α-keto heterocycles
US5618792A (en) * 1994-11-21 1997-04-08 Cortech, Inc. Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
TW200404789A (en) 1999-03-15 2004-04-01 Axys Pharm Inc Novel compounds and compositions as protease inhibitors
WO2002051983A2 (en) 2000-12-22 2002-07-04 Axys Pharmaceuticals, Inc. Novel compounds and compositions as cathepsin inhibitors
US7030116B2 (en) 2000-12-22 2006-04-18 Aventis Pharmaceuticals Inc. Compounds and compositions as cathepsin inhibitors
WO2003024924A1 (en) 2001-09-14 2003-03-27 Aventis Pharmaceuticals Inc. Novel compounds and compositions as cathepsin inhibitors
MXPA04004450A (es) 2001-11-14 2004-08-11 Aventis Pharma Inc Nuevos compuestos y composiciones como inhibidores de catepsina s.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU589665B2 (en) * 1985-08-14 1989-10-19 G.D. Searle & Co. Substituted dipeptide amides
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors

Also Published As

Publication number Publication date
EP0376012A2 (en) 1990-07-04
AU4721489A (en) 1990-07-05
CA2006374A1 (en) 1990-06-27
NO895230D0 (no) 1989-12-22
EP0376012A3 (en) 1992-05-06
DK661789A (da) 1990-06-28
NO895230L (no) 1990-06-28
DK661789D0 (da) 1989-12-22
IL92643A0 (en) 1990-08-31
JPH02215799A (ja) 1990-08-28
ZA899924B (en) 1990-09-26
KR900009688A (ko) 1990-07-05
PT92732A (pt) 1990-06-29

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Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: AMERICAN CYANAMID COMPANY