FI893616A - Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner. - Google Patents

Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner. Download PDF

Info

Publication number
FI893616A
FI893616A FI893616A FI893616A FI893616A FI 893616 A FI893616 A FI 893616A FI 893616 A FI893616 A FI 893616A FI 893616 A FI893616 A FI 893616A FI 893616 A FI893616 A FI 893616A
Authority
FI
Finland
Prior art keywords
isokinoliner
arylsubstituerade
eller
imidazo
hetero
Prior art date
Application number
FI893616A
Other languages
English (en)
Other versions
FI893616A0 (fi
Inventor
William Joseph Houlihan
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI893616A0 publication Critical patent/FI893616A0/fi
Publication of FI893616A publication Critical patent/FI893616A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
FI893616A 1988-07-29 1989-07-28 Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner. FI893616A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22630588A 1988-07-29 1988-07-29
US07/302,720 US4910206A (en) 1986-07-14 1989-01-27 5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists

Publications (2)

Publication Number Publication Date
FI893616A0 FI893616A0 (fi) 1989-07-28
FI893616A true FI893616A (fi) 1990-01-30

Family

ID=26920416

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893616A FI893616A (fi) 1988-07-29 1989-07-28 Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner.

Country Status (16)

Country Link
US (1) US4910206A (fi)
EP (1) EP0357550B1 (fi)
JP (1) JPH0273016A (fi)
KR (1) KR910002445A (fi)
AU (1) AU632487B2 (fi)
CA (1) CA1336503C (fi)
DE (1) DE68913397T2 (fi)
DK (1) DK372089A (fi)
ES (1) ES2062092T3 (fi)
FI (1) FI893616A (fi)
HU (1) HU206040B (fi)
IE (1) IE63243B1 (fi)
IL (1) IL91128A (fi)
NO (1) NO177485C (fi)
NZ (1) NZ230098A (fi)
PT (1) PT91302B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE84724T1 (de) * 1988-04-27 1993-02-15 Schering Corp Gewisse paf-antagonist/antihistamin-mischungen und verfahren.
US5530141A (en) * 1992-03-04 1996-06-25 Center For Innovative Technology 2,4-diaryl-1,3-dithiolanes; 2,4-diaryl-1,3-dioxolanes; 2,4-diaryl-1,3-oxathiolanes; and 2,5-diaryl-1,3-oxathiolanes for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5358938A (en) * 1992-07-13 1994-10-25 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5648486A (en) * 1992-07-13 1997-07-15 Cytomed, Inc. Compounds and methods for the treatment of inflammatory and immune disorders
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
JPH08502243A (ja) 1992-07-13 1996-03-12 サイトメッド，インコーポレイテッド 炎症性および免疫性疾患の治療のための２，５‐ジアリールテトラヒドロ‐チオフェン、‐フランおよび類似体
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) * 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
FR2756560A1 (fr) * 1996-12-04 1998-06-05 Adir Nouveaux derives de l'imidazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1076728C (zh) * 1999-02-05 2001-12-26 浙江大学 2－芳基咪唑并[2,1－a]异喹啉的衍生物及其用途
CN112574176B (zh) * 2019-09-27 2024-03-15 隆泰申医药科技(南京)有限公司 一种杂芳基类化合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101553A (en) * 1974-01-02 1978-07-18 Sandoz, Inc. Imidazo[2,1-a]isoquinolines
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
HU206114B (en) * 1986-07-14 1992-08-28 Sandoz Ag Process for producing 5-hetero- or aryl-substituted imidazo(2,1-a)iso-quinoline derivatives and pharmaceutical compositions comprising same as active ingredient

Also Published As

Publication number Publication date
EP0357550B1 (en) 1994-03-02
CA1336503C (en) 1995-08-01
AU632487B2 (en) 1993-01-07
DE68913397T2 (de) 1994-08-11
DK372089D0 (da) 1989-07-27
EP0357550A3 (en) 1991-04-03
PT91302A (pt) 1990-02-08
DE68913397D1 (de) 1994-04-07
IE63243B1 (en) 1995-04-05
ES2062092T3 (es) 1994-12-16
NO177485C (no) 1995-09-27
NO893062D0 (no) 1989-07-27
IL91128A0 (en) 1990-03-19
US4910206A (en) 1990-03-20
NO893062L (no) 1990-01-30
IL91128A (en) 1996-01-31
EP0357550A2 (en) 1990-03-07
HUT50630A (en) 1990-03-28
HU206040B (en) 1992-08-28
FI893616A0 (fi) 1989-07-28
PT91302B (pt) 1995-03-01
NZ230098A (en) 1992-02-25
JPH0273016A (ja) 1990-03-13
AU3901789A (en) 1990-02-01
NO177485B (no) 1995-06-19
KR910002445A (ko) 1991-02-25
IE892459L (en) 1990-01-29
DK372089A (da) 1990-01-30

Similar Documents

Publication Publication Date Title
FI893691A (fi) Ny injektionsspruta.
FI892534A0 (fi) Foerfarande foer framstaellning av 1,3-dioler av epoxider.
KR900700567A (ko) 2,3-디플루오로비페닐
NO892617L (no) Anti-aterogene midler.
FI893616A (fi) Ny anvaendning foer 5-hetero-aryl- eller 5-arylsubstituerade imidazo/2,1-a/ isokinoliner.
DE58902774D1 (de) Pflanztafel.
FI894629A0 (fi) Nya 3,4-diaminokinolin- och -pyridinfoereningar.
FI904047A0 (fi) Kateterrengoerare.
DE58902346D1 (de) Traenkeventil.
FI892387A (fi) Mellanprodukter foer framstaellning av 1,4-dihydro-4-oxokinolin-3-karboxylsyraestrar.
FI881829A0 (fi) 1,3-dioxaner.
FI880552A0 (fi) Substituerade 2,6-substituerade pyridinfoereningar.
DE58903112D1 (de) Kannenstock.
NO893141D0 (no) Toey-kondisjoneringsmidler.
DE58903154D1 (de) 2,2-difluorcyclopropyl-derivate.
DE58902190D1 (de) Schaelmaschine.
FI894455A0 (fi) 1,4-dihydropyridinderivat.
DE59008914D1 (de) Pyridyl-methylenamino-1,2,4-triazinone.
FI890483A (fi) Foerfarande foer framstaellning av sulfaterade alkanol- eller alkylfenoloxetylater med saenkt 1,4-dioxanhalt.
IT1229579B (it) 10 norantracicline.
ES2015605B3 (es) 3,4-dihidro-2h-piranos.
FI910246A0 (fi) Foerfarande foer enantiospecifik syntetisering av hexahydrobenso/d/nafto/2,1-b/azepiners mellanprodukter.
DE58903712D1 (de) Gegenseheinrichtung.
DE58900554D1 (de) Aminoguanidinoazine.
FI880081A (fi) 2,1-bensotiazepin-2,2-dioxid-5 -karboxylsyraderivat.

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: SANDOZ AG