FI884473A - A process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives - Google Patents

A process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives Download PDF

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Publication number
FI884473A
FI884473A FI884473A FI884473A FI884473A FI 884473 A FI884473 A FI 884473A FI 884473 A FI884473 A FI 884473A FI 884473 A FI884473 A FI 884473A FI 884473 A FI884473 A FI 884473A
Authority
FI
Finland
Prior art keywords
phenoxyalkylpyrocatechol
derivatives
preparation
therapeutically useful
therapeutically
Prior art date
Application number
FI884473A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI92188B (en
FI884473A0 (en
FI92188C (en
Inventor
Matthew Carson
Ru-Jen Lee Han
Ronald Andrew Lemahieu
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI884473A0 publication Critical patent/FI884473A0/en
Publication of FI884473A publication Critical patent/FI884473A/en
Publication of FI92188B publication Critical patent/FI92188B/en
Application granted granted Critical
Publication of FI92188C publication Critical patent/FI92188C/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
FI884473A 1987-10-01 1988-09-29 Process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives FI92188C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10378987A 1987-10-01 1987-10-01
US10378987 1987-10-01
US22347088A 1988-07-22 1988-07-22
US22347088 1988-07-22

Publications (4)

Publication Number Publication Date
FI884473A0 FI884473A0 (en) 1988-09-29
FI884473A true FI884473A (en) 1989-04-02
FI92188B FI92188B (en) 1994-06-30
FI92188C FI92188C (en) 1994-10-10

Family

ID=26800855

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884473A FI92188C (en) 1987-10-01 1988-09-29 Process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives

Country Status (18)

Country Link
EP (1) EP0310126B1 (en)
JP (1) JPH01128953A (en)
KR (1) KR890006559A (en)
AR (1) AR247546A1 (en)
AU (1) AU632266B2 (en)
CA (1) CA1328279C (en)
DE (1) DE3883335D1 (en)
DK (1) DK549888A (en)
ES (1) ES2058203T3 (en)
FI (1) FI92188C (en)
HU (1) HU204751B (en)
IL (1) IL87876A0 (en)
MC (1) MC1981A1 (en)
NO (1) NO169835C (en)
NZ (1) NZ226371A (en)
PH (1) PH25869A (en)
PT (1) PT88634B (en)
YU (1) YU182588A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191108A (en) * 1987-10-01 1993-03-02 Hoffmann-La Roche Inc. Catechol carboxylic acids
DE3903988A1 (en) * 1989-02-10 1990-08-30 Basf Ag OXIDIZED DIPHENYLHETEROALKANES, THEIR PREPARATION AND USE
US4937371A (en) * 1989-02-21 1990-06-26 Hoffmann-La Roche Inc. Dihydroxynaphthalene derivatives
FR2653119B1 (en) * 1989-10-18 1994-08-05 Lipha NOVEL ARYLOXY ALCOYL BENZENES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
US5374772A (en) * 1992-12-08 1994-12-20 Hoffmann-Laroche Inc. Substituted benzoic acids, inhibitors of phospholipases A2
AU6575498A (en) * 1997-03-20 1998-10-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury
CN101735048A (en) * 2008-11-05 2010-06-16 上海慈瑞医药科技有限公司 Salicylic acid compounds with insulin-sensitizing activity and preparation method thereof
FR2984730A1 (en) 2011-12-22 2013-06-28 Diverchim NEW ANTI-AGE AND DEPIGMENTING COSMETIC COMPOSITIONS
EP4276089A3 (en) * 2016-03-03 2023-12-20 Universite De Moncton Modulators of lipoxygenase and cyclooxygenase enzyme activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125059A1 (en) * 1981-06-26 1983-01-05 Bayer Ag, 5090 Leverkusen DIOXYBENZOLETHER DERIVATIVES, THESE MEDICINAL PRODUCTS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Also Published As

Publication number Publication date
NO884361L (en) 1989-04-03
MC1981A1 (en) 1989-11-23
AU632266B2 (en) 1992-12-24
PH25869A (en) 1991-12-02
AR247546A1 (en) 1995-01-31
AU2332488A (en) 1989-04-06
DE3883335D1 (en) 1993-09-23
DK549888D0 (en) 1988-09-30
NO169835C (en) 1992-08-12
FI92188B (en) 1994-06-30
NZ226371A (en) 1992-12-23
JPH01128953A (en) 1989-05-22
NO169835B (en) 1992-05-04
DK549888A (en) 1989-04-02
FI884473A0 (en) 1988-09-29
CA1328279C (en) 1994-04-05
HUT48192A (en) 1989-05-29
KR890006559A (en) 1989-06-14
PT88634B (en) 1992-12-31
EP0310126B1 (en) 1993-08-18
EP0310126A2 (en) 1989-04-05
EP0310126A3 (en) 1990-09-26
NO884361D0 (en) 1988-09-30
ES2058203T3 (en) 1994-11-01
PT88634A (en) 1988-10-01
YU182588A (en) 1990-04-30
IL87876A0 (en) 1989-03-31
FI92188C (en) 1994-10-10
HU204751B (en) 1992-02-28

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Owner name: F. HOFFMANN-LA ROCHE AG

BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG