FI874470A - Antracyklin-glykosider med antitumoeraktivitet, deras framstaellning, mellanprodukter daerav och kompositioner och anvaendning daerav. - Google Patents

Antracyklin-glykosider med antitumoeraktivitet, deras framstaellning, mellanprodukter daerav och kompositioner och anvaendning daerav. Download PDF

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Publication number
FI874470A
FI874470A FI874470A FI874470A FI874470A FI 874470 A FI874470 A FI 874470A FI 874470 A FI874470 A FI 874470A FI 874470 A FI874470 A FI 874470A FI 874470 A FI874470 A FI 874470A
Authority
FI
Finland
Prior art keywords
daerav
och
glycosider
derase
antracyklin
Prior art date
Application number
FI874470A
Other languages
English (en)
Other versions
FI874470A0 (fi
Inventor
Alberto Bargiotti
Teresa Bordoni
Pierangelo Zini
Sergio Penco
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI874470A0 publication Critical patent/FI874470A0/fi
Publication of FI874470A publication Critical patent/FI874470A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI874470A 1986-10-15 1987-10-12 Antracyklin-glykosider med antitumoeraktivitet, deras framstaellning, mellanprodukter daerav och kompositioner och anvaendning daerav. FI874470A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8624687A GB2196626B (en) 1986-10-15 1986-10-15 Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor

Publications (2)

Publication Number Publication Date
FI874470A0 FI874470A0 (fi) 1987-10-12
FI874470A true FI874470A (fi) 1988-04-16

Family

ID=10605771

Family Applications (1)

Application Number Title Priority Date Filing Date
FI874470A FI874470A (fi) 1986-10-15 1987-10-12 Antracyklin-glykosider med antitumoeraktivitet, deras framstaellning, mellanprodukter daerav och kompositioner och anvaendning daerav.

Country Status (21)

Country Link
US (1) US4839346A (fi)
JP (1) JPS63258485A (fi)
AU (1) AU7955087A (fi)
BE (1) BE1000407A4 (fi)
CA (1) CA1289950C (fi)
DE (1) DE3734476A1 (fi)
DK (1) DK533087A (fi)
ES (1) ES2007419A6 (fi)
FI (1) FI874470A (fi)
FR (1) FR2605321B1 (fi)
GB (1) GB2196626B (fi)
GR (1) GR871576B (fi)
HU (1) HU198505B (fi)
IL (1) IL84146A0 (fi)
IT (1) IT1226375B (fi)
MY (1) MY102186A (fi)
NL (1) NL8702436A (fi)
NZ (1) NZ222113A (fi)
PT (1) PT85916A (fi)
SE (1) SE8703999L (fi)
ZA (1) ZA877681B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
FR2636949A1 (fr) * 1988-09-28 1990-03-30 Hoechst Sa Laboratoires Nouveaux analogues de la desoxy-4 daunosamine, procede de preparation, anthracyclines obtenues a l'aide de ces analogues et utilisation desdites anthracyclines en tant que medicaments
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9028105D0 (en) * 1990-12-27 1991-02-13 Erba Carlo Spa Process for the preparation of substituted benzofuran derivatives
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
US6235776B1 (en) 1998-11-12 2001-05-22 Cell Pathways, Inc. Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
US6235782B1 (en) 1998-11-12 2001-05-22 Rifat Pamukcu Method for treating a patient with neoplasia by treatment with a platinum coordination complex

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
US4254110A (en) * 1979-02-02 1981-03-03 Farmitalia Carlo Erba S.P.A. Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
US4275192A (en) * 1979-05-03 1981-06-23 G. D. Searle & Co. Bis(4-demethoxydaunorubicin)dihydrazone derivatives and pharmacologically acceptable salts thereof
US4345068A (en) * 1979-11-22 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics

Also Published As

Publication number Publication date
PT85916A (pt) 1988-11-30
GB8624687D0 (en) 1986-11-19
HU198505B (en) 1989-10-30
DK533087A (da) 1988-04-16
NZ222113A (en) 1989-11-28
DE3734476A1 (de) 1988-04-21
BE1000407A4 (fr) 1988-11-22
IT8722202A0 (it) 1987-10-09
FR2605321B1 (fr) 1989-07-07
ES2007419A6 (es) 1989-06-16
NL8702436A (nl) 1988-05-02
CA1289950C (en) 1991-10-01
US4839346A (en) 1989-06-13
GB2196626B (en) 1990-09-19
ZA877681B (en) 1988-06-29
AU7955087A (en) 1988-04-21
DK533087D0 (da) 1987-10-12
FR2605321A1 (fr) 1988-04-22
JPS63258485A (ja) 1988-10-25
FI874470A0 (fi) 1987-10-12
SE8703999L (sv) 1988-04-16
HUT46030A (en) 1988-09-28
SE8703999D0 (sv) 1987-10-14
GB2196626A (en) 1988-05-05
IL84146A0 (en) 1988-03-31
MY102186A (en) 1992-04-30
IT1226375B (it) 1991-01-11
GR871576B (en) 1988-02-17

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A