FI873632A0 - NYA ANALOGER AV HYPOCALCEMICAL POLYPEPTIC FOUNDATION, SOM BEVARAR ORGANISMENS KALCIUM, DERAS FRAMSTAELLNING, DERAS ANVAENDNING SOM LAEKEMEDEL OCH DESSA INNEHAOLLANDE SAMMANSAETTNINGAR. - Google Patents

NYA ANALOGER AV HYPOCALCEMICAL POLYPEPTIC FOUNDATION, SOM BEVARAR ORGANISMENS KALCIUM, DERAS FRAMSTAELLNING, DERAS ANVAENDNING SOM LAEKEMEDEL OCH DESSA INNEHAOLLANDE SAMMANSAETTNINGAR.

Info

Publication number
FI873632A0
FI873632A0 FI873632A FI873632A FI873632A0 FI 873632 A0 FI873632 A0 FI 873632A0 FI 873632 A FI873632 A FI 873632A FI 873632 A FI873632 A FI 873632A FI 873632 A0 FI873632 A0 FI 873632A0
Authority
FI
Finland
Prior art keywords
som
deras
organismens
kalcium
hypocalcemical
Prior art date
Application number
FI873632A
Other languages
Finnish (fi)
Other versions
FI873632A (en
FI87795B (en
FI87795C (en
Inventor
Gerard Milhaud
Original Assignee
Gerard Milhaud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerard Milhaud filed Critical Gerard Milhaud
Publication of FI873632A0 publication Critical patent/FI873632A0/en
Publication of FI873632A publication Critical patent/FI873632A/en
Publication of FI87795B publication Critical patent/FI87795B/en
Application granted granted Critical
Publication of FI87795C publication Critical patent/FI87795C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Polypeptidic compounds saving the calcium of the organism, preparation thereof, application thereof as medicaments and compositions containing them. Analogues of natural hypocalcemic dotriacontapeptides characterized by the presence of asparagine respectively: a) either in position 2 with a cysteine in position 1,7; b) or in position 1 with an aminosuberic residue in position 1,7. Said polypeptides may be used as active principle for new medicaments which are particularly indicated for osteoporoses of various etiologies.
FI873632A 1985-12-24 1987-08-21 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC POLICEPTIDERS FI87795C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8519113A FR2592049B1 (en) 1985-12-24 1985-12-24 NOVEL ANALOGS OF HYPOCALCEMIC POLYPEPTIDE COMPOUNDS SPARING THE CALCIUM OF THE ORGANISM, THEIR PREPARATION AND THE MEDICAMENTS CONTAINING THESE ACTIVE INGREDIENTS
FR8519113 1985-12-24
PCT/FR1986/000440 WO1987003884A1 (en) 1985-12-24 1986-12-19 New analogues of hypocalcemic polypeptidic compounds saving the calcium of the organism, preparation thereof, application thereof as medicaments and compositions containing them
FR8600440 1986-12-19

Publications (4)

Publication Number Publication Date
FI873632A0 true FI873632A0 (en) 1987-08-21
FI873632A FI873632A (en) 1987-08-21
FI87795B FI87795B (en) 1992-11-13
FI87795C FI87795C (en) 1993-02-25

Family

ID=9326119

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873632A FI87795C (en) 1985-12-24 1987-08-21 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC POLICEPTIDERS

Country Status (13)

Country Link
EP (1) EP0232650B1 (en)
JP (1) JPH0813838B2 (en)
AT (1) ATE48616T1 (en)
CA (1) CA1273750A (en)
DE (1) DE3667472D1 (en)
DK (1) DK436187A (en)
ES (1) ES2012456B3 (en)
FI (1) FI87795C (en)
FR (1) FR2592049B1 (en)
GR (1) GR3000279T3 (en)
IE (1) IE59489B1 (en)
PT (1) PT84011B (en)
WO (1) WO1987003884A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE124705T1 (en) * 1989-11-08 1995-07-15 Daicel Chem PEPTIDES AND METHOD FOR PRODUCING CYCLIC PEPTIDES.
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
ES2055665B1 (en) * 1993-02-03 1995-03-01 Lipotec Sa PROCEDURE FOR THE OBTAINING OF CARBOCALCITONINE.
US5962270A (en) * 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
US4401593A (en) * 1982-02-12 1983-08-30 Armour Pharmaceutical Company Glycine - 8 calcitonin
US4537716A (en) * 1983-12-05 1985-08-27 Armour Pharmaceutical Co. Des-serine2 or des-glycine2 -leucine22 calcitonin
JPS60123500A (en) * 1983-12-08 1985-07-02 Mitsubishi Petrochem Co Ltd Novel calcitonin and its collection method
US4528132A (en) * 1984-01-13 1985-07-09 Armour Pharmaceutical Company [16-Alanine]calcitonin
JPS61112099A (en) * 1984-11-06 1986-05-30 Mitsubishi Petrochem Co Ltd Novel polypeptide and preparation thereof

Also Published As

Publication number Publication date
ATE48616T1 (en) 1989-12-15
CA1273750A (en) 1990-09-04
WO1987003884A1 (en) 1987-07-02
EP0232650B1 (en) 1989-12-13
ES2012456B3 (en) 1990-04-01
FR2592049B1 (en) 1988-02-12
DK436187D0 (en) 1987-08-21
PT84011B (en) 1989-07-31
EP0232650A1 (en) 1987-08-19
GR3000279T3 (en) 1991-03-15
FI873632A (en) 1987-08-21
JPS63502343A (en) 1988-09-08
FR2592049A1 (en) 1987-06-26
FI87795B (en) 1992-11-13
PT84011A (en) 1987-01-01
JPH0813838B2 (en) 1996-02-14
DK436187A (en) 1987-10-23
DE3667472D1 (en) 1990-01-18
FI87795C (en) 1993-02-25
IE59489B1 (en) 1994-03-09
IE863386L (en) 1987-06-24

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Owner name: MILHAUD, GERARD