FI873489A0 - FREQUENCY FRAGMENTATION OF 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION. - Google Patents

FREQUENCY FRAGMENTATION OF 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION.

Info

Publication number
FI873489A0
FI873489A0 FI873489A FI873489A FI873489A0 FI 873489 A0 FI873489 A0 FI 873489A0 FI 873489 A FI873489 A FI 873489A FI 873489 A FI873489 A FI 873489A FI 873489 A0 FI873489 A0 FI 873489A0
Authority
FI
Finland
Prior art keywords
dion
androstadien
androsten
frequency fragmentation
fragmentation
Prior art date
Application number
FI873489A
Other languages
Finnish (fi)
Other versions
FI873489A (en
Inventor
Alfred Weber
Mario Kennecke
Johannes Kurzidim
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI873489A0 publication Critical patent/FI873489A0/en
Publication of FI873489A publication Critical patent/FI873489A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Process for manufacturing 4-androstene-3,17 dion and 1,4 androstadiene-3,17-dion of the general formula (I) where ..... is a simple bond or a double bond, characterized by the fact that alpha -sitosterine of formula (II) is fermented with a culture of a strain of micro-organisms suitable for breaking down the lateral sterine chain.
FI873489A 1985-12-13 1987-08-11 FREQUENCY FRAGMENTATION OF 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION. FI873489A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853544662 DE3544662A1 (en) 1985-12-13 1985-12-13 METHOD FOR PRODUCING 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION
PCT/DE1986/000508 WO1987003620A1 (en) 1985-12-13 1986-12-09 Process for producing 4-androstene-3,17-dion and 1,4-androstadiene-3,17-dion

Publications (2)

Publication Number Publication Date
FI873489A0 true FI873489A0 (en) 1987-08-11
FI873489A FI873489A (en) 1987-08-11

Family

ID=6288680

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873489A FI873489A (en) 1985-12-13 1987-08-11 FREQUENCY FRAGMENTATION OF 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION.

Country Status (17)

Country Link
EP (1) EP0227588B1 (en)
JP (1) JPH0720439B2 (en)
AT (1) ATE69268T1 (en)
AU (1) AU6772887A (en)
BG (1) BG50613A3 (en)
CA (1) CA1302923C (en)
CS (1) CS271347B2 (en)
DD (1) DD254025A5 (en)
DE (2) DE3544662A1 (en)
DK (1) DK419587A (en)
ES (1) ES2038601T3 (en)
FI (1) FI873489A (en)
GR (1) GR3003640T3 (en)
HU (1) HUT44082A (en)
NO (1) NO873381L (en)
SU (1) SU1679977A3 (en)
WO (1) WO1987003620A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071714A (en) 1998-03-26 2000-06-06 Forbes Medi-Tech, Inc. Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
KR100422161B1 (en) 2001-05-11 2004-03-10 (주)유진사이언스 A method for preparation of Androst-4-ene-3,17-dione and Androsta-1,4-diene-3,17-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4826549B1 (en) * 1968-11-14 1973-08-11
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
JPS512670Y2 (en) * 1971-06-28 1976-01-26
US4293645A (en) * 1976-03-01 1981-10-06 The Upjohn Company Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
DE2703645C3 (en) * 1976-03-01 1981-11-12 The Upjohn Co., 49001 Kalamazoo, Mich. Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
JPS52115548A (en) * 1976-03-24 1977-09-28 Matsushita Electric Ind Co Ltd Heat pump type air conditioning system

Also Published As

Publication number Publication date
HUT44082A (en) 1988-01-28
CA1302923C (en) 1992-06-09
SU1679977A3 (en) 1991-09-23
FI873489A (en) 1987-08-11
CS928286A2 (en) 1990-02-12
DE3682379D1 (en) 1991-12-12
JPS63501922A (en) 1988-08-04
CS271347B2 (en) 1990-09-12
EP0227588A1 (en) 1987-07-01
DE3544662A1 (en) 1987-06-19
AU6772887A (en) 1987-06-30
ATE69268T1 (en) 1991-11-15
BG50613A3 (en) 1992-09-15
JPH0720439B2 (en) 1995-03-08
ES2038601T3 (en) 1993-08-01
NO873381D0 (en) 1987-08-12
NO873381L (en) 1987-08-12
DK419587D0 (en) 1987-08-12
DK419587A (en) 1987-08-12
EP0227588B1 (en) 1991-11-06
WO1987003620A1 (en) 1987-06-18
DD254025A5 (en) 1988-02-10
GR3003640T3 (en) 1993-03-16

Similar Documents

Publication Publication Date Title
AU8581991A (en) Mercaptoacetylamide derivatives as inhibitors of enkephalinase and ACE, and processes for their production
DE3685764D1 (en) ANTIBIOTIC PRODUCED BY LYSOBACTER SP. SC 14,067.
ATE106451T1 (en) FERMENTATION PROCESS FOR THE PRODUCTION OF 2-KETO-L-GULONIC ACID.
FI853910L (en) FOERBAETTRAT FOERFARANDE FOER FRAMSTAELLNING AV A-21978C-DERIVAT.
FI873489A0 (en) FREQUENCY FRAGMENTATION OF 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION.
ES8700652A1 (en) Method for producing glyoxylylspermidine and the use thereof for the production of 15-deoxy spergualin-related compounds
GR3007079T3 (en)
NZ221020A (en) Substituted benzonitriles
DE3687100D1 (en) CLAVAME DERIVATIVES, PRODUCTION AND INTERMEDIATE PRODUCTS.
ATE105860T1 (en) GENE AND GENE PRODUCT FOR THE PRODUCTION OF BETA- LACTAM COMPOUNDS.
DE69016693D1 (en) Cultivation of transformed microorganisms.
ZA848194B (en) Perfumery compounds and their preparations
SE8504409D0 (en) NOVEL CHEMICAL INTERMEDIATES
ATE144285T1 (en) MICROBIOLOGICAL PROCESS FOR PRODUCING 5-HYDROXY-2-PYRAZINECARBONIC ACID
FI903459A0 (en) Process for Preparation of Antitumor Antibiotic BU-3285T or BU-3285T Desulfate
TH1619EX (en) L-glutamic acid production process
AU616168C (en) Novel microorganisms and a method for production of glutamic acid using the same
CA2062667A1 (en) Microbiological process for the production of 6-hydroxynicotinic acid
AU1161488A (en) Novel microorganisms and a method for production of glutamic acid using the same
DE69432304D1 (en) CLAVULIC ACID DEHYDROGENASE, PRODUCTION AND USE FOR THE PRODUCTION OF CLAVULIC ACID
EP0186520A3 (en) Nocardia microorganisms and antibiotic product thereof
NO872824D0 (en) INTERMEDIATES FOR THE PRODUCTION OF CEPHALOSPORINES.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT