BG50613A3 - Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion - Google Patents

Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion

Info

Publication number
BG50613A3
BG50613A3 BG080473A BG8047387A BG50613A3 BG 50613 A3 BG50613 A3 BG 50613A3 BG 080473 A BG080473 A BG 080473A BG 8047387 A BG8047387 A BG 8047387A BG 50613 A3 BG50613 A3 BG 50613A3
Authority
BG
Bulgaria
Prior art keywords
dion
image
androstadiene
androsten
preparation
Prior art date
Application number
BG080473A
Other languages
Bulgarian (bg)
Inventor
Alfred Weber
Mario Kennecke
Johannes Kurzidim
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG50613A3 publication Critical patent/BG50613A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/005Degradation of the lateral chains at position 17

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

This method is used to derive 4-androstane-3,17-dion and 1,4-androstane-3,17-dion with a common formula<IMAGE>where <IMAGE> is a single or binary bond. α-cytosterin with a formula<IMAGE>is subject to fermentation with a strain sample extracted from a micro organism, which may implement disintegration of the lateral chain of the sterynes.
BG080473A 1985-12-13 1987-07-07 Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion BG50613A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853544662 DE3544662A1 (en) 1985-12-13 1985-12-13 METHOD FOR PRODUCING 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION
PCT/DE1986/000508 WO1987003620A1 (en) 1985-12-13 1986-12-09 Process for producing 4-androstene-3,17-dion and 1,4-androstadiene-3,17-dion

Publications (1)

Publication Number Publication Date
BG50613A3 true BG50613A3 (en) 1992-09-15

Family

ID=6288680

Family Applications (1)

Application Number Title Priority Date Filing Date
BG080473A BG50613A3 (en) 1985-12-13 1987-07-07 Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion

Country Status (17)

Country Link
EP (1) EP0227588B1 (en)
JP (1) JPH0720439B2 (en)
AT (1) ATE69268T1 (en)
AU (1) AU6772887A (en)
BG (1) BG50613A3 (en)
CA (1) CA1302923C (en)
CS (1) CS271347B2 (en)
DD (1) DD254025A5 (en)
DE (2) DE3544662A1 (en)
DK (1) DK419587A (en)
ES (1) ES2038601T3 (en)
FI (1) FI873489A0 (en)
GR (1) GR3003640T3 (en)
HU (1) HUT44082A (en)
NO (1) NO873381D0 (en)
SU (1) SU1679977A3 (en)
WO (1) WO1987003620A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071714A (en) 1998-03-26 2000-06-06 Forbes Medi-Tech, Inc. Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
KR100422161B1 (en) 2001-05-11 2004-03-10 (주)유진사이언스 A method for preparation of Androst-4-ene-3,17-dione and Androsta-1,4-diene-3,17-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4826549B1 (en) * 1968-11-14 1973-08-11
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
JPS512670Y2 (en) * 1971-06-28 1976-01-26
DE2703645C3 (en) * 1976-03-01 1981-11-12 The Upjohn Co., 49001 Kalamazoo, Mich. Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
US4293645A (en) * 1976-03-01 1981-10-06 The Upjohn Company Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
JPS52115548A (en) * 1976-03-24 1977-09-28 Matsushita Electric Ind Co Ltd Heat pump type air conditioning system

Also Published As

Publication number Publication date
DE3544662A1 (en) 1987-06-19
CS928286A2 (en) 1990-02-12
HUT44082A (en) 1988-01-28
CS271347B2 (en) 1990-09-12
WO1987003620A1 (en) 1987-06-18
DD254025A5 (en) 1988-02-10
SU1679977A3 (en) 1991-09-23
JPH0720439B2 (en) 1995-03-08
JPS63501922A (en) 1988-08-04
GR3003640T3 (en) 1993-03-16
FI873489A (en) 1987-08-11
DK419587D0 (en) 1987-08-12
EP0227588B1 (en) 1991-11-06
DK419587A (en) 1987-08-12
NO873381L (en) 1987-08-12
NO873381D0 (en) 1987-08-12
CA1302923C (en) 1992-06-09
ATE69268T1 (en) 1991-11-15
FI873489A0 (en) 1987-08-11
AU6772887A (en) 1987-06-30
DE3682379D1 (en) 1991-12-12
ES2038601T3 (en) 1993-08-01
EP0227588A1 (en) 1987-07-01

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