BG50613A3 - Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion - Google Patents
Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dionInfo
- Publication number
- BG50613A3 BG50613A3 BG080473A BG8047387A BG50613A3 BG 50613 A3 BG50613 A3 BG 50613A3 BG 080473 A BG080473 A BG 080473A BG 8047387 A BG8047387 A BG 8047387A BG 50613 A3 BG50613 A3 BG 50613A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- dion
- image
- androstadiene
- androsten
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- AEMFNILZOJDQLW-QAGGRKNESA-N androst-4-ene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 AEMFNILZOJDQLW-QAGGRKNESA-N 0.000 title 1
- LUJVUUWNAPIQQI-QAGGRKNESA-N androsta-1,4-diene-3,17-dione Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 LUJVUUWNAPIQQI-QAGGRKNESA-N 0.000 title 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
This method is used to derive 4-androstane-3,17-dion and 1,4-androstane-3,17-dion with a common formula<IMAGE>where <IMAGE> is a single or binary bond. α-cytosterin with a formula<IMAGE>is subject to fermentation with a strain sample extracted from a micro organism, which may implement disintegration of the lateral chain of the sterynes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853544662 DE3544662A1 (en) | 1985-12-13 | 1985-12-13 | METHOD FOR PRODUCING 4-ANDROSTEN-3,17-DION AND 1,4-ANDROSTADIEN-3,17-DION |
PCT/DE1986/000508 WO1987003620A1 (en) | 1985-12-13 | 1986-12-09 | Process for producing 4-androstene-3,17-dion and 1,4-androstadiene-3,17-dion |
Publications (1)
Publication Number | Publication Date |
---|---|
BG50613A3 true BG50613A3 (en) | 1992-09-15 |
Family
ID=6288680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG080473A BG50613A3 (en) | 1985-12-13 | 1987-07-07 | Method for the preparation of 4- androsten- 3, 17- dion and 1, 4- androstadiene- 3, 17- dion |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0227588B1 (en) |
JP (1) | JPH0720439B2 (en) |
AT (1) | ATE69268T1 (en) |
AU (1) | AU6772887A (en) |
BG (1) | BG50613A3 (en) |
CA (1) | CA1302923C (en) |
CS (1) | CS271347B2 (en) |
DD (1) | DD254025A5 (en) |
DE (2) | DE3544662A1 (en) |
DK (1) | DK419587A (en) |
ES (1) | ES2038601T3 (en) |
FI (1) | FI873489A0 (en) |
GR (1) | GR3003640T3 (en) |
HU (1) | HUT44082A (en) |
NO (1) | NO873381D0 (en) |
SU (1) | SU1679977A3 (en) |
WO (1) | WO1987003620A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6071714A (en) | 1998-03-26 | 2000-06-06 | Forbes Medi-Tech, Inc. | Process for the microbial conversion of phytosterols to androstenedione and androstadienedione |
KR100422161B1 (en) | 2001-05-11 | 2004-03-10 | (주)유진사이언스 | A method for preparation of Androst-4-ene-3,17-dione and Androsta-1,4-diene-3,17-dione |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4826549B1 (en) * | 1968-11-14 | 1973-08-11 | ||
US3684657A (en) * | 1970-05-11 | 1972-08-15 | Searle & Co | Selective microbiological degradation of steroidal 17-alkyls |
US3759791A (en) * | 1970-12-10 | 1973-09-18 | Searle & Co | Selective microbiological preparation of androst-4-ene-3,17-dione |
JPS512670Y2 (en) * | 1971-06-28 | 1976-01-26 | ||
DE2703645C3 (en) * | 1976-03-01 | 1981-11-12 | The Upjohn Co., 49001 Kalamazoo, Mich. | Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione |
US4293645A (en) * | 1976-03-01 | 1981-10-06 | The Upjohn Company | Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione |
JPS52115548A (en) * | 1976-03-24 | 1977-09-28 | Matsushita Electric Ind Co Ltd | Heat pump type air conditioning system |
-
1985
- 1985-12-13 DE DE19853544662 patent/DE3544662A1/en not_active Withdrawn
-
1986
- 1986-12-09 JP JP62500101A patent/JPH0720439B2/en not_active Expired - Lifetime
- 1986-12-09 AU AU67728/87A patent/AU6772887A/en not_active Abandoned
- 1986-12-09 WO PCT/DE1986/000508 patent/WO1987003620A1/en active Application Filing
- 1986-12-09 ES ES198686730207T patent/ES2038601T3/en not_active Expired - Lifetime
- 1986-12-09 AT AT86730207T patent/ATE69268T1/en not_active IP Right Cessation
- 1986-12-09 DE DE86730207T patent/DE3682379D1/de not_active Expired - Fee Related
- 1986-12-09 EP EP86730207A patent/EP0227588B1/en not_active Expired - Lifetime
- 1986-12-09 HU HU86458A patent/HUT44082A/en unknown
- 1986-12-12 CS CS869282A patent/CS271347B2/en not_active IP Right Cessation
- 1986-12-12 CA CA000525244A patent/CA1302923C/en not_active Expired - Lifetime
- 1986-12-12 DD DD86297530A patent/DD254025A5/en not_active IP Right Cessation
-
1987
- 1987-07-07 BG BG080473A patent/BG50613A3/en unknown
- 1987-08-10 SU SU4203113A patent/SU1679977A3/en active
- 1987-08-11 FI FI873489A patent/FI873489A0/en not_active IP Right Cessation
- 1987-08-12 NO NO873381A patent/NO873381D0/en unknown
- 1987-08-12 DK DK419587A patent/DK419587A/en not_active Application Discontinuation
-
1992
- 1992-01-23 GR GR910402032T patent/GR3003640T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE3544662A1 (en) | 1987-06-19 |
CS928286A2 (en) | 1990-02-12 |
HUT44082A (en) | 1988-01-28 |
CS271347B2 (en) | 1990-09-12 |
WO1987003620A1 (en) | 1987-06-18 |
DD254025A5 (en) | 1988-02-10 |
SU1679977A3 (en) | 1991-09-23 |
JPH0720439B2 (en) | 1995-03-08 |
JPS63501922A (en) | 1988-08-04 |
GR3003640T3 (en) | 1993-03-16 |
FI873489A (en) | 1987-08-11 |
DK419587D0 (en) | 1987-08-12 |
EP0227588B1 (en) | 1991-11-06 |
DK419587A (en) | 1987-08-12 |
NO873381L (en) | 1987-08-12 |
NO873381D0 (en) | 1987-08-12 |
CA1302923C (en) | 1992-06-09 |
ATE69268T1 (en) | 1991-11-15 |
FI873489A0 (en) | 1987-08-11 |
AU6772887A (en) | 1987-06-30 |
DE3682379D1 (en) | 1991-12-12 |
ES2038601T3 (en) | 1993-08-01 |
EP0227588A1 (en) | 1987-07-01 |
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