FI812539L - Substituerade enantolaktamderivat som antihypertensiva medel - Google Patents

Substituerade enantolaktamderivat som antihypertensiva medel

Info

Publication number
FI812539L
FI812539L FI812539A FI812539A FI812539L FI 812539 L FI812539 L FI 812539L FI 812539 A FI812539 A FI 812539A FI 812539 A FI812539 A FI 812539A FI 812539 L FI812539 L FI 812539L
Authority
FI
Finland
Prior art keywords
enantolactamderivat
antihypertensiva
medel
som
substitute
Prior art date
Application number
FI812539A
Other languages
English (en)
Inventor
Elbert E Harris
Arthur A Patchett
Eugene D Thorsett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI812539L publication Critical patent/FI812539L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI812539A 1980-08-18 1981-08-17 Substituerade enantolaktamderivat som antihypertensiva medel FI812539L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17914180A 1980-08-18 1980-08-18
US28097181A 1981-07-07 1981-07-07

Publications (1)

Publication Number Publication Date
FI812539L true FI812539L (fi) 1982-02-19

Family

ID=26875027

Family Applications (1)

Application Number Title Priority Date Filing Date
FI812539A FI812539L (fi) 1980-08-18 1981-08-17 Substituerade enantolaktamderivat som antihypertensiva medel

Country Status (10)

Country Link
EP (1) EP0046289B1 (fi)
DE (1) DE3173064D1 (fi)
DK (1) DK364381A (fi)
ES (1) ES8301216A1 (fi)
FI (1) FI812539L (fi)
GR (1) GR74624B (fi)
IL (1) IL63540A0 (fi)
NO (1) NO812773L (fi)
PL (1) PL232685A1 (fi)
PT (1) PT73529A (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3260831D1 (en) * 1981-06-05 1984-10-31 Merck & Co Inc Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
EP0107095B1 (en) * 1982-09-30 1987-09-09 Merck & Co. Inc. 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4537885A (en) * 1983-02-10 1985-08-27 Ciba Geigy Corporation Certain benzazocinone and benzazoninone derivatives
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
US4533661A (en) * 1983-03-28 1985-08-06 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-amino-2-oxo-1H-azepine-1-acetic acid derivatives having anti-hypertensive activity
US4598071A (en) * 1983-03-28 1986-07-01 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-amino-2-oxo-1H-azocine or azonine-1-acetic acid derivatives having anti-hypertensive properties
US4567167A (en) * 1983-03-28 1986-01-28 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-2-oxo-piperidine-1-acetic acid derivatives having anti-hypertensive activity
US4474778A (en) * 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
US4699905A (en) * 1984-04-10 1987-10-13 Sankyo Company, Limited Perhydrothiazepine derivatives, their preparation and their therapeutic use
EP0187037A3 (en) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Piperidine derivatives, their production and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4192875A (en) * 1979-02-02 1980-03-11 Merck & Co., Inc. Cyclic hexapeptide
US4377515A (en) * 1979-10-01 1983-03-22 Merck & Co., Inc. Long lasting agonists and antagonists of LH-RH

Also Published As

Publication number Publication date
EP0046289A2 (en) 1982-02-24
EP0046289B1 (en) 1985-11-27
EP0046289A3 (en) 1982-04-28
ES504790A0 (es) 1982-12-01
NO812773L (no) 1982-02-19
DE3173064D1 (en) 1986-01-09
GR74624B (fi) 1984-06-29
ES8301216A1 (es) 1982-12-01
IL63540A0 (en) 1981-11-30
DK364381A (da) 1982-02-19
PL232685A1 (fi) 1982-04-26
PT73529A (en) 1981-09-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: MERCK & CO INC